Viral mechanisms

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Pathogenicity & virulence status

Topics: 2,676 Posts: 2,933

Last Post: Ital J Pediatr . Risk factors analysis of poor prognosis in ICU-admitted children with severe influenza pneumonia: a retrospective case-control study

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2,933

Ital J Pediatr . Risk factors analysis of poor prognosis in ICU-admitted children with severe influenza pneumonia: a retrospective case-control study

by tetano

June 10, 2026, 01:16 AM

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Immune response (26/60)	Host binding ability (226/279)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (139/143)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 73 Posts: 171

Last Post: Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

171

Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

by tetano

December 13, 2025, 03:04 AM

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HA RBS (9/10)	HA - cleavage (3/62)	NA (7/7)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 265 Posts: 279

Last Post: J Virol . Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission

265

279

J Virol . Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission

by tetano

March 27, 2026, 03:52 AM

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Influenza Other Respir Viruses . Postinfection Pig and Ferret Antisera Show Similar Antigenic Profiles for Human Influenza A(H1N1pdm09) Viruses by tetano Started by tetano, April 25, 2026, 02:01 AM	0 responses 20 views 0 likes	Last Post by tetano April 25, 2026, 02:01 AM
Emerg Microbes Infect . Airway organoids reveal patterns of influenza A tropism and adaptation in wildlife species by tetano Started by tetano, April 22, 2026, 04:01 AM	0 responses 22 views 0 likes	Last Post by tetano April 22, 2026, 04:01 AM
mSphere . Bacterial alteration of redox stressors impacts environmental stability of influenza A virus by tetano Started by tetano, April 22, 2026, 03:15 AM	0 responses 21 views 0 likes	Last Post by tetano April 22, 2026, 03:15 AM
Dokl Biochem Biophys . A New Model for the Transmembrane Heterocomplex of Hemagglutinin HA and Ionic Channel M2 Proteins in Influenza A Virus by tetano Started by tetano, April 22, 2026, 02:32 AM	0 responses 16 views 0 likes	Last Post by tetano April 22, 2026, 02:32 AM
J Infect Dis . Distinct inflammatory programming of thoracic cavity white adipose immune cells regulates influenza pathogenesis by tetano Started by tetano, April 11, 2026, 01:28 AM	0 responses 22 views 0 likes	Last Post by tetano April 11, 2026, 01:28 AM
Front Immunol . Estimating time since influenza virus exposure using single-cell proteomic data by tetano Started by tetano, April 8, 2026, 01:49 AM	0 responses 23 views 0 likes	Last Post by tetano April 8, 2026, 01:49 AM
J Med Virol . Replication Fitness of Human Influenza B Viruses in Swine Primary Respiratory Epithelial Cells by tetano Started by tetano, April 1, 2026, 04:27 AM	0 responses 21 views 0 likes	Last Post by tetano April 1, 2026, 04:27 AM
Virol J . Secondary analysis of influenza a virus-infected cells at single-cell resolution reveals host BANF1 response to individual and combinations of detected segments by tetano Started by tetano, March 27, 2026, 04:25 AM	0 responses 18 views 0 likes	Last Post by tetano March 27, 2026, 04:25 AM
PLoS One . Internal gene segments from a mouse-adapted influenza B virus confer increased pathogenicity to mice by tetano Started by tetano, March 27, 2026, 04:02 AM	0 responses 28 views 0 likes	Last Post by tetano March 27, 2026, 04:02 AM
Front Immunol . Metabolic reprogramming induced by CRP deficiency or human CRP transgenic in influenza-infected mice by tetano Started by tetano, March 27, 2026, 03:41 AM	0 responses 20 views 0 likes	Last Post by tetano March 27, 2026, 03:41 AM

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