Infect Dis Clin North Am. 2013 Mar;27(1):49-69. doi: 10.1016/j.idc.2012.11.012.
What Is the Role of Newer Molecular Tests in the Management of CAP?
Gaydos CA.
Source
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, 530 Rangos Building, 800 North Wolfe Street, Baltimore, MD 21205, USA. Electronic address: cgaydos@jhmi.edu.
Abstract
Community-acquired pneumonia (CAP) accounts for major morbidity and mortality in the United States. With improved broad-spectrum antibiotics, the implementation of diagnostic studies has declined and most patients do not have an etiologic pathogen of CAP identified. To enhance the appropriate use of antiviral agents and prevent overuse of antibiotics, the successful management of CAP requires rapid and accurate diagnosis of the etiologic agent of CAP. This article provides an overview of the new rapid molecular tests for the diagnosis of influenza, other respiratory viruses, and bacteria compared with nonmolecular tests and how their use for directed therapy can enhance and improve the management of CAP.
Copyright ? 2013 Elsevier Inc. All rights reserved.
PMID:
23398865
[PubMed - in process]
What Is the Role of Newer Molecular Tests in the Management of CAP?
Gaydos CA.
Source
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, 530 Rangos Building, 800 North Wolfe Street, Baltimore, MD 21205, USA. Electronic address: cgaydos@jhmi.edu.
Abstract
Community-acquired pneumonia (CAP) accounts for major morbidity and mortality in the United States. With improved broad-spectrum antibiotics, the implementation of diagnostic studies has declined and most patients do not have an etiologic pathogen of CAP identified. To enhance the appropriate use of antiviral agents and prevent overuse of antibiotics, the successful management of CAP requires rapid and accurate diagnosis of the etiologic agent of CAP. This article provides an overview of the new rapid molecular tests for the diagnosis of influenza, other respiratory viruses, and bacteria compared with nonmolecular tests and how their use for directed therapy can enhance and improve the management of CAP.
Copyright ? 2013 Elsevier Inc. All rights reserved.
PMID:
23398865
[PubMed - in process]