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Ebola's Secret Weapon Revealed

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  • Ebola's Secret Weapon Revealed

    Source: http://www.sciencedaily.com/releases...0502192226.htm

    Ebola's Secret Weapon Revealed

    May 2, 2013 ? Researchers have discovered the mechanism behind one of the Ebola virus' most dangerous attributes: its ability to disarm the adaptive immune system.

    University of Texas Medical Branch at Galveston scientists determined that Ebola short-circuits the immune system using proteins that work together to shut down cellular signaling related to interferon. Disruption of this activity, the researchers found, allows Ebola to prevent the full development of dendritic cells that would otherwise trigger an immune response to the virus...

    ...Journal Reference:

    N. M. Lubaki, P. Ilinykh, C. Pietzsch, B. Tigabu, A. N. Freiberg, R. A. Koup, A. Bukreyev. The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains. Journal of Virology, 2013; DOI: 10.1128/JVI.03316-12
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