## WHO ignores the risk from lab-escapes or human(e.g. "terrorist") deliberately
## created and released viruses
## so presumably they consider that risk smaller than the ones that they mention
WHO May.10.2013 on H7N9 : The risk has not changed since Apr.13
WHO,Apr.26.2013 on H5N1 : Therefore, the public health risk remains unchanged.
WHO,Apr.13.2013,H7N9
What is the risk of the occurrence of further cases in the affected areas of China and other areas?
The epidemiology of this virus among animals, including the main reservoirs of infection among
animals and the extent of geographic spread, is not yet established. However, it is likely that most
human H7N9 infections so far are associated with infection among as-of-yet undetermined animals
and that further human cases of infection should be expected.
What is the risk of human-to-human transmission?
There is no evidence of sustained human-to-human transmission. However the two possible family
clusters suggest that limited human-to-human transmission may occur where there is close contact
between cases and other individuals, as occurs in families and, potentially, healthcare settings.
Moreover, the genetic changes seen among these viruses suggesting adaptation to mammals is of
concern, and further adaptation may occur.
What is the risk of international spread?
At this time, there is no information to indicate international spread of this virus. However, it is
possible that an infected person, who may or may not have symptoms, could travel to another
country. However, if the virus cannot sustain human-to-human transmission, as appears to be the
current situation, then extensive community spread is unlikely
WHO,Mar.12.2013,H5N1,unchanged
WHO,Feb.15,2013,H5N1,unchanged
WHO,Jan.16.2013,H5N1,unchanged
WHO,Dec.17.2012,H5N1,unchanged
WHO,05.Nov.2012,H5N1,unchanged
WHO,01.Oct.2012 ,H5N1, unchanged.
10 September 2012
Public health risk assessment for avian influenza A(H5N1) viruses: The public health risk for the virus
remain unchanged.
10 August 2012
Overall public health risk assessment for avian influenza A(H5N1) viruses: Two sporadic human cases
reported this month in a country with known endemic influenza A(H5N1) virus circulation in poultry is
within the expected range. From the data available, there is no evidence of onward sustained human
to human transmission at this time hence the public health risk for the virus remains unchanged.
25 June 2012
Overall public health risk assessment: Based on previous years observations, a decrease in reported
events in poultry is expected for this time of year. One sporadic case reported this month in the
country with known influenza A(H5N1) virus circulation in poultry is within the expected range. From
the data available there is no risk of onward sustained human to human transmission.
04 June 2012
Overall public health risk assessment: A decrease in reported events in poultry is expected for this
time of year. Two sporadic cases reported this month in countries with known influenza A(H5N1)
circulation in poultry are within the expected range. These sporadic cases do not appear to have
features that would raise concern regarding onward sustained human to human transmission.
07 May 2012
Overall public health risk assessment: Poultry outbreaks and sporadic human cases and small clusters
would be expected at this time of year. These sporadic cases do not appear to have features that
would raise concern regarding onward sustained human to human transmission.
02 April 2012
Overall public health risk assessment: Poultry outbreaks and sporadic human cases and small clusters
would be expected at this time of year. These sporadic cases do not appear to have features that
would raise concern regarding onward sustained human to human transmission.
05 March 2012
Overall public health risk assessment: an increase in poultry outbreaks and sporadic human cases and
small clusters would be expected at this time of year. Further investigations around the mild cases
detected in Bangladesh are awaited to define public health risk
06 February 2012
Overall public health risk assessment: an increase in poultry outbreaks and sporadic human cases and
small clusters would be expected at this time of year. No further spread has apparently occurred;
therefore the risk to public health has not changed from what would be expected this time of year.
09 January 2012
Epidemiologic investigations have identified only limited human‐to‐human transmission of this virus since its
emergence in 2003, and no community‐level transmission has been noted. Therefore, the sporadic cases and
small clusters being reported are not considered unusual and are not thought to indicate any increase in
public health risk. As well, recent reported evolution of the H5N1 virus is not thought to indicate any increase
in public health risk3.
05 December 2011
Therefore, the sporadic cases
and small clusters being reported are not considered unusual and are not thought to indicate any
increase in public health risk. As well, recent reported evolution of the H5N1 virus is not thought to
indicate any increase in public health risk3.
07 November 2011
03 October 2011
05 September 2011
30 August 2011
Evolution of H5N1 avian influenza virus does not increase risk to public health
WHO closely monitors the evolution of influenza viruses and is aware of recent reports of an H5N1 virus
(described as H5N1 clade 2.3.2.1) circulating in poultry in parts of Asia. Based on available information,
# this evolution of the H5N1 virus poses no increased risk to public health. It is not considered unusual
because influenza viruses are constantly evolving, especially in areas where they circulate regularly in
poultry. The WHO Global Influenza Surveillance and Response System, the group of experts that studies
animal and human influenza viruses that may impact human health, recognized this new clade in February
2011.WHO also routinely assesses the public health risk from all animal influenza viruses. Based on available
information, the identification of this newly-reported H5N1 virus clade does not change the current public
health implications of the H5N1 avian influenza viruses for humans. Human cases of H5N1 infection remain
rare and sporadic events, occurring mostly in areas where H5N1 viruses circulate regularly in poultry.
Human cases could occur wherever the viruses are present in poultry and when humans might be exposed
to infected birds or contaminated environments.
03 August 2011
04 July 2011
17 June 2011 Low pathogenicity H7 viruses are also currently circulating in poultry in
Europe and China. These viruses likely do not pose a significant risk to public health
currently, but warrant consistent monitoring and control in animal populations.
## created and released viruses
## so presumably they consider that risk smaller than the ones that they mention
WHO May.10.2013 on H7N9 : The risk has not changed since Apr.13
WHO,Apr.26.2013 on H5N1 : Therefore, the public health risk remains unchanged.
WHO,Apr.13.2013,H7N9
What is the risk of the occurrence of further cases in the affected areas of China and other areas?
The epidemiology of this virus among animals, including the main reservoirs of infection among
animals and the extent of geographic spread, is not yet established. However, it is likely that most
human H7N9 infections so far are associated with infection among as-of-yet undetermined animals
and that further human cases of infection should be expected.
What is the risk of human-to-human transmission?
There is no evidence of sustained human-to-human transmission. However the two possible family
clusters suggest that limited human-to-human transmission may occur where there is close contact
between cases and other individuals, as occurs in families and, potentially, healthcare settings.
Moreover, the genetic changes seen among these viruses suggesting adaptation to mammals is of
concern, and further adaptation may occur.
What is the risk of international spread?
At this time, there is no information to indicate international spread of this virus. However, it is
possible that an infected person, who may or may not have symptoms, could travel to another
country. However, if the virus cannot sustain human-to-human transmission, as appears to be the
current situation, then extensive community spread is unlikely
WHO,Mar.12.2013,H5N1,unchanged
WHO,Feb.15,2013,H5N1,unchanged
WHO,Jan.16.2013,H5N1,unchanged
WHO,Dec.17.2012,H5N1,unchanged
WHO,05.Nov.2012,H5N1,unchanged
WHO,01.Oct.2012 ,H5N1, unchanged.
10 September 2012
Public health risk assessment for avian influenza A(H5N1) viruses: The public health risk for the virus
remain unchanged.
10 August 2012
Overall public health risk assessment for avian influenza A(H5N1) viruses: Two sporadic human cases
reported this month in a country with known endemic influenza A(H5N1) virus circulation in poultry is
within the expected range. From the data available, there is no evidence of onward sustained human
to human transmission at this time hence the public health risk for the virus remains unchanged.
25 June 2012
Overall public health risk assessment: Based on previous years observations, a decrease in reported
events in poultry is expected for this time of year. One sporadic case reported this month in the
country with known influenza A(H5N1) virus circulation in poultry is within the expected range. From
the data available there is no risk of onward sustained human to human transmission.
04 June 2012
Overall public health risk assessment: A decrease in reported events in poultry is expected for this
time of year. Two sporadic cases reported this month in countries with known influenza A(H5N1)
circulation in poultry are within the expected range. These sporadic cases do not appear to have
features that would raise concern regarding onward sustained human to human transmission.
07 May 2012
Overall public health risk assessment: Poultry outbreaks and sporadic human cases and small clusters
would be expected at this time of year. These sporadic cases do not appear to have features that
would raise concern regarding onward sustained human to human transmission.
02 April 2012
Overall public health risk assessment: Poultry outbreaks and sporadic human cases and small clusters
would be expected at this time of year. These sporadic cases do not appear to have features that
would raise concern regarding onward sustained human to human transmission.
05 March 2012
Overall public health risk assessment: an increase in poultry outbreaks and sporadic human cases and
small clusters would be expected at this time of year. Further investigations around the mild cases
detected in Bangladesh are awaited to define public health risk
06 February 2012
Overall public health risk assessment: an increase in poultry outbreaks and sporadic human cases and
small clusters would be expected at this time of year. No further spread has apparently occurred;
therefore the risk to public health has not changed from what would be expected this time of year.
09 January 2012
Epidemiologic investigations have identified only limited human‐to‐human transmission of this virus since its
emergence in 2003, and no community‐level transmission has been noted. Therefore, the sporadic cases and
small clusters being reported are not considered unusual and are not thought to indicate any increase in
public health risk. As well, recent reported evolution of the H5N1 virus is not thought to indicate any increase
in public health risk3.
05 December 2011
Therefore, the sporadic cases
and small clusters being reported are not considered unusual and are not thought to indicate any
increase in public health risk. As well, recent reported evolution of the H5N1 virus is not thought to
indicate any increase in public health risk3.
07 November 2011
03 October 2011
05 September 2011
30 August 2011
Evolution of H5N1 avian influenza virus does not increase risk to public health
WHO closely monitors the evolution of influenza viruses and is aware of recent reports of an H5N1 virus
(described as H5N1 clade 2.3.2.1) circulating in poultry in parts of Asia. Based on available information,
# this evolution of the H5N1 virus poses no increased risk to public health. It is not considered unusual
because influenza viruses are constantly evolving, especially in areas where they circulate regularly in
poultry. The WHO Global Influenza Surveillance and Response System, the group of experts that studies
animal and human influenza viruses that may impact human health, recognized this new clade in February
2011.WHO also routinely assesses the public health risk from all animal influenza viruses. Based on available
information, the identification of this newly-reported H5N1 virus clade does not change the current public
health implications of the H5N1 avian influenza viruses for humans. Human cases of H5N1 infection remain
rare and sporadic events, occurring mostly in areas where H5N1 viruses circulate regularly in poultry.
Human cases could occur wherever the viruses are present in poultry and when humans might be exposed
to infected birds or contaminated environments.
03 August 2011
04 July 2011
17 June 2011 Low pathogenicity H7 viruses are also currently circulating in poultry in
Europe and China. These viruses likely do not pose a significant risk to public health
currently, but warrant consistent monitoring and control in animal populations.
Comment