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Influenza evolution navigates stability valleys

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  • Influenza evolution navigates stability valleys

    Elife. 2013 May 14;2:e00842. doi: 10.7554/eLife.00842. Print 2013.
    Influenza evolution navigates stability valleys.
    Rorick MM, Pascual M.
    Source

    is at the Department of Ecology and Evolutionary Biology , University of Michigan , Ann Arbor , United States rorick@umich.edu.
    Abstract

    By reconstructing how an influenza protein collected in 1968 might have evolved into one collected in 2007, researchers have obtained new insights into the interactions between genetic mutations.
    KEYWORDS:

    Viruses, epistasis, influenza, protein evolution, protein instability

    PMID:
    23682318
    [PubMed]
    PMCID:
    PMC3654458

    Free PMC Article

    By reconstructing how an influenza protein collected in 1968 might have evolved into one collected in 2007, researchers have obtained new insights into the interactions between genetic mutations.
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