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  • Pigs as H5N1 Vectors

    Pigs as Vectors Discussion.
    <!-- / message -->
    Last edited by sharon sanders; May 20, 2006, 06:08 AM.

  • #2
    Re: Pigs

    I have a question.

    Pigs have been blamed as the intermidiary host in '57 & '68 due to their having a2, 3 & A2, 6 binding sites and close contact with amn and poultry in an agricultural setting. What I expected to see - and haven't - is a lot of testing for H5N1 (and known human flus) antibodies in swine in an attempt to find out if they are being infected by one or both.

    My question is - can anyone update me or provide links please?

    Thanks
    JJ

    Comment


    • #3
      Re: Dangerous Cluster Sizes

      Originally posted by AlaskaDenise
      Other interesting information about clusters here and here.
      Thanks, AlaskaDenise. I guess the problem is that there is no "technical definition" of clusters. We are not yet seeing Osterholm's 10-20 cluster at a time, but it does appear that the most recent Indonesian cluster is "larger". I guess I was asking an epidemiological modeling question. What would be a best guesstimate for the reproductive number of H5N1 based on current human influenza? Second given this number, at what cluster size, i.e. how many nodes or individuals, would it be impossible to contain even with isolation and Tamiflu blanket? That of course, would be the tipping point for me.
      http://novel-infectious-diseases.blogspot.com/

      Comment


      • #4
        Re: Ask general questions here

        Al:

        I hope you've read the article on ROs here.

        What would be a best guesstimate for the reproductive number of H5N1 based on current human influenza?
        I've wondered this also, but haven't had time to run any numbers. I would venture that BlueJay on CE may be doing just that for Indonesia. I would assume we can apply the theory to only one region of particularly active uncontrolled mutations, since a pandemic mutation need happen only once.

        I think we're trying to measure the distance between a theoretical statistical "certainty" (RO theory) and any final H2H mutation, which is of <100% certain components. We're close to the definition of both points, but not able to apply any yardstick.

        .

        We can't fall into the "if science can't describe it, it mustn't exist" trap - but I don't expect people on this forum to have that problem.
        "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

        Comment


        • #5
          Are we at the pandemic doorstep?

          Are we at the pandemic doorstep?
          May 14, 2006

          mmigratory birds return to Qinghai

          Indonesia
          8 family cluster - 6 dead?
          12 cluster?
          HCW infected
          128 suspected

          Djibouti
          3 child cluster
          fever in town since april

          India
          Jwaradamma is stronger than chikungunya is spreading faster

          Comment


          • #6
            Re: Ask general questions here

            We cannot make any affirmation now, Goju, but if this is it, it will go exponential, we are trying to find some informations concerning the other 12 persons.

            If we still have informations we would know by the end of the week.

            But please read



            the context certainly impose some cautiousness.

            Comment


            • #7
              Re: Pigs

              Originally posted by JJackson
              I have a question.

              Pigs have been blamed as the intermidiary host in '57 & '68 due to their having a2, 3 & A2, 6 binding sites and close contact with amn and poultry in an agricultural setting. What I expected to see - and haven't - is a lot of testing for H5N1 (and known human flus) antibodies in swine in an attempt to find out if they are being infected by one or both.

              My question is - can anyone update me or provide links please?

              Thanks
              JJ


              Studies of H5N1 Influenza Virus Infection of Pigs by Using Viruses Isolated in Vietnam and Thailand in 2004
              Young Ki Choi,1,7 Tien Dzung Nguyen,2 Hiroichi Ozaki,1,8 Richard J. Webby,1 Pilaipan Puthavathana,3 Chantanee Buranathal,4 Arunee Chaisingh,3 Prasert Auewarakul,4 N. T. H. Hanh,5 Sia Kit Ma,6 Pui Yan Hui,6 Yi Guan,6 Joseph Sriyal Malik Peiris,6 and Robert G. Webster1*

              ABSTRACT

              To determine whether avian H5N1 influenza viruses associated with human infections in Vietnam had transmitted to pigs, we investigated serologic evidence of exposure to H5N1 influenza virus in Vietnamese pigs in 2004. Of the 3,175 pig sera tested, 8 (0.25%) were positive for avian H5N1 influenza viruses isolated in 2004 by virus neutralization assay and Western blot analysis. Experimental studies of replication and transmissibility of the 2004 Asian H5N1 viruses in pigs revealed that all viruses tested replicated in the swine respiratory tract but none were transmitted to contact pigs. Virus titers from nasal swabs peaked on day 2, and low titers were detected in the liver of two of the four pigs tested. Our findings indicate that pigs can be infected with highly lethal Asian H5N1 viruses but that these viruses are not readily transmitted between pigs under experimental conditions.

              Comment


              • #8
                Re: Ask general questions here

                Mingus,

                Can we make a credible parralel between efficient transmission between pigs and efficient transmission between humans ??

                Is the above studies and the know history between efficient Pigs to Humans transmission, thus studying strain in pigs and efficient transmission between them would indeed be a sign of easiness transmission between humans. ???

                Comment


                • #9
                  Re: Ask general questions here

                  SO,


                  I think we could do that parralel. But there are numerous strain of swine influenza that could not be transmitted pig-2-human so this parralel is to handle with caution.
                  Restiratory tract of pigs express both a-2,3 and a-2,6 proteoglycans and is commonly tought of being the ideal mixing vessels to accomodate both avian and human strain.

                  Historitically, swine influenza haved always been of the sames subtype that those infecting humans (H1N1, H3N2, H1N2)
                  In america, there is two major H1N1 clades in swine, one originating from the 1918 pandemic strain the other from an avian souce.
                  The swine H3N2 is a tought to be a recombination of the classicalswineH1N1 and human virus. It appear in UnitedStated around 1998.
                  This H3N2 had create an epidemic last year in Canada but was further change since his Neuraminidase was of human origin.
                  This strain is tought to also infect turkey birds and to produce many kind of reassortment event between human, swine and avian virus !

                  Related articles:

                  Reassortment of H3N2 and H1N1 (can produce H1N2, H3N1 )
                  Since the introduction of H3N2 swine influenza viruses (SIVs) into U.S. swine in 1998, H1N2 and H1N1 reassortant viruses have emerged from reassortment between classical H1N1 and H3N2 viruses. In 2004, a new reassortant H3N1 virus (A/Swine/Minnesota/00395/2004) was identified from coughing pigs. Phy …


                  Limitation for the swine to human and reverse transmission linked to H and N gene
                  Influenza A viruses cause pandemics at sporadic intervals. Pandemic viruses can potentially be introduced into the human population through in toto transfer of an avian influenza virus or through reassortment between avian and human strains. Pigs are believed to play a central role in the creation o …


                  Swine H3N2 infect turkey farm in US (note that the canadian strain with the Human origin "N" had also infect turkey in Ontario manitoba and BC)
                  In 1998, a novel H3N2 reassortant virus emerged in the United States swine population. We report the interspecies transmission of this virus to turkeys in two geographically distant farms in the United States in 2003. This event is of concern, considering the reassortment capacity of this virus and …


                  So in therm of influenza infectivity Human and Pigs are not the same but are "Brother Species"

                  Comment


                  • #10
                    Re: Ask general questions here

                    Many thanks Mingus, exactly what I was looking for.

                    JJ

                    Comment


                    • #11
                      Re: Ask general questions here

                      JJackson.
                      look this one , extremely recent.
                      Not even published yet, we just haved the abstract...

                      Comment


                      • #12
                        Re: Pigs as H5N1 Vectors

                        Plague Hits Krasnodar Pigs



                        A scientific research institute in Vladimir has confirmed that 896 pigs that have died since Feb. 16 on a farm in the Krasnodar region were afflicted with "classic plague," Interfax reported Monday.

                        The farm has been placed under quarantine, a source in the regional Emergency Situations Ministry told Interfax. More than 100 carcasses have already been burned.

                        Workers at the farm are currently vaccinating the remaining healthy animals. A source in the regional office of the Federal Veterinary and Phytosanitary Inspection Service told Interfax that the dead animals had never been vaccinated. (MT)


                        Comment


                        • #13
                          Re: Pigs as H5N1 Vectors

                          with the new H2N3 in pigs

                          I thought, I should make a table
                          of swine viruses and consider their human-avian mixing properties.

                          See also here for the human-avian markers
                          and here for the "humanity" scores (any ideas for a better terminology ?)


                          swine genomes from genbank 31.Dec.2007
                          ---------------------------------------
                          Code:
                          #avian markers
                          #human markers
                          total humanity-score (ratio of A,T nucleotides)
                          humanity score for the 8 segments
                          32 marker-positions
                          virus name
                          00 28 5573:5553,5621,5620,5812,5367,5557,5199,5730,AMATLDAEEK PDRVSLTAST GILRFQ VTT IS- >A/swine/Shandong/2/03(H5N1)
                          00 28 5656:5660,5766,5692,5790,5453,5715,5296,5665,AMAILDVEAK PDRVSLAAST SILRFQ VTT IP- >A/swine/Spain/42386/2002(H3N2)
                          00 29 5674:5683,5764,5688,5823,5474,5808,5207,5745,AMAILDAEAK PDRVSLAAST SILRFQ VTT IPG >A/swine/Spain/39139/2002(H3N2)
                          00 29 5710:5764,5706,5708,5955,5486,5821,5276,5813,AMAILDAEAK PDRVSLAAST GILRFQ VTT IS- >A/swine/Spain/53207/2004(H1N1)
                          00 30 5571:5540,5694,5620,5857,5252,5622,5209,5542,AIATLDAEAK PDRVSLAAST GILRFQ VTT -PE >A/swine/Henan/wy/2004(H5N1)
                          00 30 5623:5660,5685,5589,5866,5352,5768,5226,5660,AMATLDAVAK PDRVSLAAST GILRFQ VTT IPG >A/swine/Virginia/671/1987(H1N1)
                          00 30 5624:5664,5685,5589,5877,5345,5768,5216,5660,AMATLDAVAK PDRVSLAAST GILRFQ VTT IPG >A/swine/Virginia/670/1987(H1N1)
                          00 30 5668:5738,5680,5694,5889,5409,5800,5236,5684,AMAILDAEAK PDRVSLAAST GILRFQ VTT IPG >A/Swine/Spain/50047/2003(H1N1)
                          00 30 5681:5706,5712,5705,5861,5530,5749,5247,5754,AMAILDAEAK PDRVSLAAST GILRFQ VTT IPG >A/swine/Spain/33601/2001(H3N2)
                          00 30 5698:5764,5728,5712,5991,5489,5711,5220,5719,AMAILDAEAK PDRVSLAAST GILRFQ VTT IPG >A/swine/Spain/51915/2003(H1N1)
                          00 30 5724:5751,5756,5747,6016,5469,5774,5285,5788,AMAILDAEAK PDRVSLAAST GILRFQ VTT IP- >A/swine/Cloppenburg/IDT4777/2005(H1N2)
                          00 30 5726:5760,5756,5718,6034,5455,5823,5265,5800,AMAILDAEAK PDRVSLAAST GILRFQ VTT IP- >A/swine/Doetlingen/IDT4735/2005(H1N2)
                          00 31 5588:5557,5694,5593,5857,5309,5720,5209,5554,AMATLDAEAK PDRVSLAAST GILRFQ VTT -PE >A/swine/Fujian/F1/2001(H5N1)
                          00 31 5593:5553,5698,5588,5855,5322,5733,5256,5546,AMATLDAEAK PDRVSLAAST GILRFQ VTT -PE >A/swine/Fujian/1/2003(H5N1)
                          00 32 5531:5515,5689,5584,5670,5287,5627,5031,5561,AMATLDAEAK PDRVSLAAST GILRFQ VTT IPE >A/Swine/Ontario/01911-1/99 (H4N6)
                          01 27 5587:5574,5647,5615,5849,5246,5696,5180,5775,AMATLDTEAK PDRISLAANT GILRFQ VTT IS- >A/swine/Guangxi/FS2/2005(H9N2)
                          01 27 5598:5565,5745,5611,5820,5252,5682,5189,5775,AMATLDTEAK PDRISLAANT GILRFQ VTT IS- >A/swine/Guangxi/S15/2005(H9N2)
                          01 27 5598:5570,5736,5606,5820,5233,5689,5228,5775,AMATLDTEAK PDRISLAANT GILRFQ VTT IS- >A/swine/Guangxi/S11/2005(H9N2)
                          01 28 5595:5544,5732,5597,5843,5252,5703,5189,5775,AMATLDAEAK PDRISLAANT GILRFQ VTT IS- >A/swine/Guangxi/58/2005(H9N2)
                          01 28 5668:5620,5709,5677,5927,5444,5842,5265,5747,AMATLDAEVK PDRVSLAANT GILRFQ VTT VPG >A/swine/Italy/1521/98(H1N2)
                          01 28 5679:5672,5755,5720,5831,5455,5804,5247,5767,AMAILDVEAK PDQVSLAAST GILRFQ VTT IP- >A/swine/Spain/54008/2004(H3N2)
                          01 29 5592:5530,5730,5629,5857,5335,5654,5199,5577,CMATLDAEAR PDRVSLAAST GILRFQ VTT -PE >A/swine/Guangxi/wz/2004(H5N1)
                          01 30 5623:5538,5750,5680,5822,5331,5843,5180,5674,AMATLDAEAK PDRVSLAANT GILRFQ VTT VPE >A/swine/Korea/S452/2004(H9N2)
                          01 31 5525:5521,5637,5588,5708,5230,5702,5040,5501,AMATLDAEAK PDQVSLAAST GILRFQ VTT IPE >A/swine/Ontario/K01477/01(H3N3)
                          01 31 5527:5469,5712,5555,5620,5223,5680,5193,5596,AMATLDAEAK PDRVSLAANT GILRFQ VTT IPE >A/swine/Saskatchewan/18789/02(H1N1)
                          01 31 5527:5513,5637,5583,5708,5243,5709,5061,5501,AMATLDAEAK PDQVSLAAST GILRFQ VTT IPE >A/swine/Ontario/42729A/01(H3N3)
                          03 24 5646:5537,5831,5614,5861,5404,5750,5308,5710,AMAALDTEEK PDRVSLAAST GMLKFR VAT IP- >A/swine/Missouri/2124514/2006(H2N3)
                          03 24 5653:5546,5830,5645,5859,5423,5764,5307,5684,AMAALDTEEK PDRVSLAAST GMLKFR VAT IP- >A/swine/Missouri/4296424/2006(H2N3)
                          04 25 5619:5534,5750,5602,5767,5427,5893,5208,5610,AMAALDTEEK PDRVSLAAST GILKFK VAT IP- >A/swine/Minnesota/00395/2004(H3N1)
                          04 26 5596:5494,5775,5541,5766,5476,5695,5323,5562,AMASLDAEAK PDRVSLAANT GILKFK VAT IP- >A/Swine/Iowa/569/99 (H3N2)
                          04 26 5596:5494,5775,5541,5775,5469,5702,5314,5567,AMASLDAEAK PDRVSLAANT GILKFK VAT IP- >A/Swine/Iowa/533/99 (H3N2)
                          04 26 5600:5494,5775,5541,5763,5507,5687,5345,5573,AMASLDAEAK PDRVSLAANT GILKFK VAT IP- >A/Swine/Minnesota/593/99 (H3N2)
                          04 26 5616:5494,5775,5541,5775,5629,5709,5301,5584,AMASLDAEAK PDRVSLAANT GILKFK VAT IP- >A/Swine/Nebraska/209/98 (H3N2)
                          05 24 5582:5491,5760,5569,5726,5438,5702,5213,5572,AMAALDTEAK SDRVSLAANT GILKFK VAT IP- >A/swine/British Columbia/28103/2005(H3N2)
                          05 24 5585:5491,5778,5555,5737,5445,5695,5213,5596,AMAALDTEAK SDRVSLAANT GILKFK VAT IP- >A/swine/Alberta/14722/2005(H3N2)
                          05 24 5585:5500,5791,5550,5731,5432,5695,5213,5584,AMAALDTEAK SDRVSLAANT GILKFK VAT IP- >A/swine/Manitoba/12707/2005(H3N2)
                          05 24 5589:5491,5773,5578,5737,5438,5716,5213,5584,AMAALDTEAK SDRVSLAANT GILKFK VAT IP- >A/swine/Ontario/33853/2005(H3N2)
                          05 24 5641:5541,5767,5603,5804,5491,5879,5281,5632,AMAALDTEAK SDRVSLAANT GILKFK VAT IP- >A/swine/MI/PU243/04 (H3N1)
                          05 25 5594:5514,5770,5563,5747,5467,5687,5239,5590,AMAALDTEAK PDRVSLAANT GILKFK VAT IP- >A/swine/North Carolina/2003(H3N2)
                          05 25 5612:5531,5785,5544,5894,5419,5698,5230,5597,AMAALDAEAK PDRVSLAANT GILKFK VAT IS- >A/Swine/Indiana/9K035/99 (H1N2)
                          05 25 5624:5514,5756,5561,5993,5421,5767,5231,5546,AMAALDTEAK PDRVSLAANT GILKFK VAT IP- >A/Swine/Korea/CY02/02(H1N2)
                          05 25 5632:5533,5800,5583,5755,5480,5916,5268,5539,AMAALDTEAK PDRVSLAANT GILKFK VAT IP- >A/swine/Korea/PZ72-1/2006(H3N1)
                          05 25 5638:5535,5800,5583,5755,5480,6009,5268,5515,AMAALDTEAK PDRVSLAANT GILKFK VAT IP- >A/swine/Korea/CN22/2006(H3N1)
                          05 25 5639:5550,5759,5612,5796,5494,5841,5310,5621,AMAALDTEAK PDRVSLAANT GILKFK VAT IP- >A/swine/IN/PU542/04 (H3N1)
                          07 21 5736:5498,5795,5877,6061,5484,5900,5359,5816,AIAALDTEAK PNRVSLAANT GILKFK IAT IS- >A/swine/Ontario/53518/03(H1N1)
                          07 22 5652:5587,5813,5599,5902,5476,5741,5326,5584,AIAALDTEAK PNRVSLASNT GILKFK VAT IP- >A/swine/Guangxi/13/2006(H1N2)
                          07 24 5597:5600,5690,5633,5789,5318,5816,5142,5524,AISTMDAKAR PNRVSLAAST GILRFQ VAT IPR >A/swine/Jamesburg/1942(H1N1)
                          07 24 5631:5608,5698,5726,5792,5424,5807,5185,5543,AISTMDAKAR PNRVSLAAST GILRFQ VAT IPR >A/swine/Ohio/23/1935(H1N1)
                          07 24 5636:5603,5721,5683,5829,5345,5907,5200,5569,AISTMDAKAR PNRVSLAAST GILRFQ VAT IPR >A/swine/1931(H1N1)
                          08 21 5728:5712,5838,5866,5937,5390,5886,5266,5580,AISTMDLKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/112/1977(H1N1)
                          08 21 5729:5714,5841,5866,5940,5381,5886,5262,5591,AISTMDLKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/105/1977(H1N1)
                          08 21 5730:5738,5806,5835,5980,5417,5888,5256,5578,AISTMDAKAK PNRVSLAANT GILKFK VAT IL- >A/swine/Tennessee/19/1976(H1N1)
                          08 21 5732:5716,5833,5865,5947,5404,5898,5266,5590,AISTMDLKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/118/1977(H1N1)
                          08 21 5733:5710,5838,5873,5951,5390,5895,5262,5596,AISTMDLKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/106/1977(H1N1)
                          08 21 5736:5707,5837,5870,5951,5404,5915,5266,5596,AISTMDLKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Arizona/148/1977(H1N1)
                          08 21 5737:5729,5837,5890,5923,5424,5877,5276,5578,AISTMDAKAK PNRVSLAANT GILKFK VAT VP- >A/swine/Iowa/1/1977(H1N1)
                          08 21 5749:5719,5854,5845,5969,5408,5898,5326,5707,AISTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Iowa/2/1985(H1N1)
                          08 21 5749:5734,5870,5849,5980,5398,5881,5286,5690,AVSTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Kansas/3024/1987(H1N1)
                          08 21 5751:5753,5882,5758,6055,5390,5829,5299,5792,AISTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Alberta/56626/03(H1N1)
                          08 21 5753:5734,5872,5849,5980,5401,5903,5286,5695,AVSTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Kansas/3228/1987(H1N1)
                          08 21 5754:5726,5854,5849,5986,5411,5905,5326,5707,AISTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Iowa/1/1985(H1N1)
                          08 21 5754:5726,5854,5850,5980,5411,5912,5326,5707,AISTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Iowa/3/1985(H1N1)
                          08 21 5754:5734,5863,5850,5974,5411,5894,5286,5751,AISTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Iowa/2/1987(H1N1)
                          08 21 5754:5745,5859,5836,5991,5443,5877,5312,5672,AISTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Iowa/1/1987(H1N1)
                          08 21 5758:5742,5841,5859,5986,5450,5884,5306,5719,AISTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Iowa/31483/1988(H1N1)
                          08 22 5722:5746,5864,5808,5881,5430,5836,5302,5543,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/8/1978(H1N1)
                          08 22 5724:5709,5811,5833,5954,5425,5872,5282,5579,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/10/1976(H1N1)
                          08 22 5724:5740,5820,5859,5886,5454,5846,5272,5555,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/5/1978(H1N1)
                          08 22 5725:5735,5858,5838,5912,5387,5867,5252,5594,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/30747/1976(H1N1)
                          08 22 5728:5729,5842,5834,5881,5469,5853,5326,5567,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/2/1978(H1N1)
                          08 22 5729:5768,5759,5867,5911,5424,5919,5276,5572,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/23/1976(H1N1)
                          08 22 5730:5738,5832,5863,5911,5411,5912,5236,5567,AISTMDAKAK PNRVSLAANT GILKFK VAT IPG >A/swine/Nebraska/123/1977(H1N1)
                          08 22 5732:5721,5831,5847,5946,5437,5877,5286,5567,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/17/1976(H1N1)
                          08 22 5732:5751,5859,5845,5928,5411,5898,5236,5532,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Kentucky/1/1976(H1N1)
                          08 22 5733:5729,5813,5837,5957,5437,5891,5286,5590,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/7/1976(H1N1)
                          08 22 5733:5729,5815,5833,5957,5437,5891,5286,5590,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/3/1976(H1N1)
                          08 22 5733:5729,5859,5832,5905,5433,5884,5326,5567,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/8/1980(H1N1)
                          08 22 5733:5751,5835,5840,5894,5463,5856,5306,5590,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/82/1977(H1N1)
                          08 22 5734:5709,5857,5840,5911,5437,5880,5326,5602,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/663/1980(H1N1)
                          08 22 5734:5729,5846,5859,5936,5417,5888,5276,5567,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Minnesota/24/1975(H1N1)
                          08 22 5734:5739,5832,5845,5946,5437,5877,5286,5551,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/15/1976(H1N1)
                          08 22 5735:5751,5843,5840,5900,5463,5859,5302,5573,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/87/1977(H1N1)
                          08 22 5735:5753,5841,5836,5894,5463,5866,5306,5585,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/84/1977(H1N1)
                          08 22 5735:5755,5846,5840,5894,5463,5859,5301,5577,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/88/1977(H1N1)
                          08 22 5736:5726,5846,5840,5917,5437,5880,5326,5602,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/661/1980(H1N1)
                          08 22 5736:5734,5850,5840,5911,5430,5880,5326,5590,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/641/1980(H1N1)
                          08 22 5737:5721,5867,5831,5917,5427,5873,5296,5672,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/11/1980(H1N1)
                          08 22 5737:5725,5814,5849,5963,5459,5884,5286,5590,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Iowa/1/1976(H1N1)
                          08 22 5737:5731,5848,5845,5911,5437,5880,5326,5608,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/629/1980(H1N1)
                          08 22 5737:5786,5780,5854,5925,5431,5908,5276,5602,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/48/1977(H1N1)
                          08 22 5738:5709,5879,5850,5917,5406,5873,5306,5655,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Ontario/1/1981(H1N1)
                          08 22 5739:5748,5877,5843,5898,5406,5856,5322,5633,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Ontario/6/1981(H1N1)
                          08 22 5739:5755,5841,5858,5939,5417,5873,5276,5590,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Iowa/4/1976(H1N1)
                          08 22 5740:5739,5872,5861,5913,5406,5849,5302,5644,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Ontario/3/1981(H1N1)
                          08 22 5740:5744,5880,5848,5913,5408,5853,5297,5644,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Ontario/2/1981(H1N1)
                          08 22 5741:5742,5872,5845,5911,5420,5873,5288,5655,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Ontario/4/1981(H1N1)
                          08 22 5741:5763,5872,5835,5928,5398,5891,5276,5614,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/10/1977(H1N1)
                          08 22 5742:5734,5837,5891,5963,5417,5877,5278,5578,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/10/1978(H1N1)
                          08 22 5742:5742,5846,5867,5951,5417,5905,5276,5567,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Minnesota/27/1976(H1N1)
                          08 22 5742:5744,5850,5835,5974,5450,5877,5296,5555,AISTMDAKAK PNRVSLAANT GILKFK VAT IPG >A/swine/Tennessee/86/1977(H1N1)
                          08 22 5743:5742,5872,5851,5934,5411,5908,5266,5614,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Minnesota/5892-7/1979(H1N1)
                          08 22 5744:5760,5824,5863,5974,5398,5912,5286,5578,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/21/1977(H1N1)
                          08 22 5744:5764,5824,5867,5974,5398,5915,5266,5578,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/19/1977(H1N1)
                          08 22 5745:5703,5850,5881,5997,5439,5891,5276,5560,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/64/1977(H1N1)
                          08 22 5745:5734,5837,5891,5969,5417,5884,5292,5578,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/11/1978(H1N1)
                          08 22 5746:5703,5848,5881,5997,5450,5891,5276,5567,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/65/1977(H1N1)
                          08 22 5746:5729,5859,5864,5951,5398,5891,5316,5660,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/1915/1988(H1N1)
                          08 22 5747:5764,5828,5863,5974,5398,5919,5276,5602,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/31/1977(H1N1)
                          08 22 5748:5768,5832,5863,5974,5404,5898,5286,5614,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/37/1977(H1N1)
                          08 22 5749:5755,5850,5854,5985,5424,5898,5296,5572,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/49/1977(H1N1)
                          08 22 5749:5760,5880,5850,5934,5414,5866,5298,5660,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Ontario/7/1981(H1N1)
                          08 22 5749:5768,5865,5834,5943,5469,5877,5278,5602,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/3/1978(H1N1)
                          08 22 5752:5693,5867,5879,5969,5452,5894,5336,5619,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Maryland/23239/1991(H1N1)
                          08 22 5753:5703,5868,5861,5974,5430,5901,5346,5648,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Iowa/24297/1991(H1N1)
                          08 22 5755:5738,5863,5863,5986,5420,5898,5316,5637,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Iowa/17672/1988(H1N1)
                          08 22 5778:5732,5941,5866,6034,5488,5798,5355,5696,AISTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Zhejiang/1/2004(H1N2)
                          09 20 5726:5801,5809,5880,5784,5417,5732,5376,5724,AISTMDAKAK PNRVSLAANT GILKFK IAT IS- >A/swine/Ontario/48235/04(H1N2)
                          09 21 5696:5632,5783,5754,5942,5456,5874,5246,5649,AISTMDAKAR PNRVSLAANT GILKFK VAT IPG >A/swine/Wisconsin/1/1957(H1N1)
                          09 21 5713:5678,5781,5811,5985,5413,5843,5282,5640,AISTMDAKAR PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/2/1966(H1N1)
                          09 21 5719:5745,5803,5850,5950,5374,5864,5227,5555,ATSTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Iowa/100/1977(H1N1)
                          09 21 5725:5701,5811,5806,5963,5437,5950,5256,5555,AISTMDAKAR PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/1/1975(H1N1)
                          09 21 5726:5699,5802,5817,5974,5430,5950,5256,5555,AISTMDAKAR PNRVSLAANT GILKFK VAT IP- >A/swine/Illinois/1/1975(H1N1)
                          09 21 5727:5738,5811,5845,5930,5417,5880,5256,5614,AISTMDAKAR PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/1/1971(H1N1)
                          09 21 5728:5755,5798,5854,5963,5391,5884,5246,5567,ATSTMDAKAK PNRVSLAANT GILKFK VAT IS- >A/swine/Tennessee/96/1977(H1N1)
                          09 21 5735:5691,5770,5839,5987,5519,5886,5278,5644,AISTMDAKAR PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/1/1967(H1N1)
                          09 21 5737:5721,5737,5854,5974,5483,5922,5256,5707,AISTMDAKAR PNRVSLAANT GILKFK VAT IP- >A/swine/Wisconsin/2/1970(H1N1)
                          09 22 5737:5757,5819,5872,5986,5391,5891,5236,5555,ATSTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/62/1977(H1N1)
                          09 22 5739:5732,5811,5876,5982,5416,5905,5276,5555,ATSTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/61/1977(H1N1)
                          09 22 5740:5752,5813,5882,5980,5404,5898,5266,5548,ATSTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/79/1977(H1N1)
                          09 22 5740:5764,5821,5881,5955,5409,5897,5258,5572,ATSTMDAKAK PNRVSLAANT GILKFK VAT IP- >A/swine/Tennessee/25/1977(H1N1)
                          10 18 5788:5771,5815,5907,6067,5447,5893,5458,5704,AISTMDTKAK PNQVSLAANT GILKFK IAT IS- >A/swine/Ontario/23866/04(H1N1)
                          10 19 5723:5776,5766,5925,5802,5389,5708,5419,5764,AISTMDAKAK PNQVSLAANT GILKFK IAT IS- >A/swine/Ontario/55383/04(H1N2)
                          12 17 5769:5785,5809,5876,6049,5444,5907,5279,5704,AISTMDIKAK LNQASLAANT GILKFK VAT IS- >A/swine/Ontario/57561/03(H1N1)
                          26 04 5659:5638,5779,5799,5749,5412,5654,5326,5696,ATSAMNIKTK LNQACISSNS DLPKYR IAA IP- >A/Swine/Shandong/3/2005(H3N2)
                          31 00 5621:5649,5769,5732,5590,5390,5659,5277,5685,STSAMSIKTR LNQACISSNS DLPKYK IAA MTR >A/swine/Heilongjiang/1/05(H3N2)
                          31 00 5638:5685,5807,5743,5626,5391,5676,5227,5665,STSAMSIKTR LNQACISSNS DLPKYK IAA MTR >A/Swine/Colorado/1/77(H3N2)
                          31 01 5704:5728,5877,5785,5866,5348,5816,5238,5651,STAAMNIKTR LNQACISSNS DLPKYK IAA MTR >A/swine/Henan/01/06(H1N1)
                          31 01 5711:5732,5865,5781,5883,5341,5854,5287,5640,STAAMNIKTR LNQACISSNS DLPKYK IAA MTR >A/swine/Tianjin/01/04(H1N1)
                          32 00 5669:5728,5807,5788,5665,5427,5730,5247,5654,STSAMNIKTR LNQACISSNS DLPKYK IAA MTR >A/Swine/Wisconsin/194/80(H3N2)
                          32 00 5675:5733,5794,5792,5719,5408,5719,5269,5695,STSAMNIKTR LNQACISSNS DLPKYK IAA MTR >A/swine/Ontario/00130/97(H3N2)
                          32 00 5696:5785,5800,5769,5829,5401,5631,5341,5777,STSAMNIKTR LNQACISSNS DLPKYK IAA MTR >A/swine/Ontario/52156/03(H1N2)
                          I'm interested in expert panflu damage estimates
                          my current links: http://bit.ly/hFI7H ILI-charts: http://bit.ly/CcRgT

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                          • #14
                            Re: Pigs as H5N1 Vectors

                            Thank you gsgs.

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