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  • Typhoid confirmed in Mozambique (and Malawi)

    I can't even imagine the cause on this one.



    UNDIAGNOSED FATALITIES - MALAWI, MOZAMBIQUE: REQUEST FOR INFORMATION
    ************************************************** ******************
    A ProMED-mail post
    <http://www.promedmail.org>
    ProMED-mail is a program of the
    International Society for Infectious Diseases
    <http://www.isid.org>

    Date: 11 Jul 2009
    Source: Nation Online, Window on Malawi [edited]
    <http://www.nationmw.net/newsdetail.asp?article_id=3384>


    Strange disease hits Neno
    -------------------------
    An unknown disease has killed 15 people out of 103 patients since May
    this year [2009] in 2 bordering villages of Mtemankhawa and Datson in
    Malawi and Mozambique, respectively. Mtemankhawa Village, with a
    total population of 753, is in the area of TA Dambe in Neno while
    Datson Village, in the area of Chief Tsangano in Mozambique, has a
    population of 329.

    Traditional leaders in the area and Secretary for Health Chris
    Kang'ombe have confirmed the occurrence of the unknown disease and
    the deaths. "It is true that 15 people out of 103 cases have died so
    far. 8 are from the Malawi side while 7 from Mozambique side. 5 are
    admitted to Neno District Hospital," said Kang'ombe in an interview
    yesterday. He described the disease as "not well known".

    The PS said the ministry has already sent laboratory samples to South
    Africa for analysis. The symptoms of the disease, according to
    Kang'ombe, include stiff neck, dehydration, fever, headache, joint
    pain, discomfort in abdomen and loss of voice. He ruled out meningitis.

    While waiting for the results of the samples, he said, the ministry
    is treating some patients with antibiotics and has supplied the
    people with Chlorine because "they use unprotected wells for water."
    He said the area is "very cold" and some people are forced not to
    bathe for many days. He said some live together with animals in their
    round grass-thatched houses which have no windows. "These could be
    some contributing factors but it is yet to be seen," said Kang'ombe.
    He said the ministry has also set up a treatment camp in the area to
    handle minor cases.

    Group Village Headman Chakulembera, who oversees Mtemankhawa Village,
    said in an interview on Wednesday [8 Jul 2009] in Mwanza that those
    affected by the disease develop stiff jaws, neck and have abdominal
    pains. "It makes it difficult for them to eat," he said.
    Chakulembera, who was flanked by village headman Mtemankhawa and T/A
    Dambe's envoy MacDonald Chindimwe, said among those killed include 5
    pupils, 3 from Chawe Primary School.

    "On average, we have 3 or 4 deaths per week. People are worried about
    the development because they cannot work in their wheat and Irish
    potato gardens," said Chakulembera, who was supported by Mtemankhawa
    who said: "The latest death was on Monday this week, 6 Jul 2009."

    The group village headman said the disease has affected almost every
    family, with some having more than one patient. Chakulembera said
    some patients died at Neno District Hospital but the majority
    succumbed at their homes. "We are living in fear. When one is
    attacked, we know he or she is going to die," he said.

    Chakulembera said health officials from both Malawi and Mozambique
    have been visiting the area "frequently" to monitor the situation.
    "The Ministry of Health supplied us with Chlorine to add to the water
    we use," confirmed Chakulembera. There is no piped water or
    boreholes. Most of the houses are old round grass-thatched ones and
    have no windows. People sleep together with animals in such houses,"
    he said when asked to explain the living conditions of the people in
    the affected area.

    On another note, Mtemankhawa said he is living in fear for his life
    after some of his villagers warned they would "deal with him. They
    accuse me of being a wizard and that I am behind the deaths. They
    make such allegations because they say I do not provide a solution.
    But it is not true," he said.

    He said villagers have since agitated for a witchdoctor to come to
    the village to find the cause of the mysterious disease. He also said
    grave-diggers have threatened to abandon their work, arguing they are
    fed up with the frequent deaths. Dambe's advisor said the chief
    advised fellow traditional leaders to tell people to stop sleeping in
    the same house with animals and ensure that all dwelling units have
    windows and pit latrines as preventive measures.

    --
    Communicated by:
    ProMED-mail
    <promed@promedmail.org>

    [The above newswire describes a clinical picture that is difficult to
    come to diagnostic conclusions on. Some of the symptoms might lead
    one to think meningitis was the etiology, but the newswire mentions
    that meningitis has been ruled out. Other symptoms might be
    compatible with the more severe form of leptospirosis, although
    arthralgias are described rather than myalgias, and jaundice is not
    mentioned where it tends to be a predominant presenting symptom with
    severe leptospirosis. According to the article, since the beginning
    of May 2009, the overall attack rate has been 9.5 percent (103 cases
    out of a total population of 1082) with a case fatality rate of 14.6
    percent. Oftentimes when one reads newswires, the presumed risk
    factors of disease mentioned helps to narrow down the etiologic
    agent. In the above newswire this isn't really the case as it
    mentions poor water and sanitation, and close proximity to animals,
    risk factors for a large spectrum of microbial agents includi!
    ng bacterial and viral agents. Note, that while this moderator is
    mentioning microbial agents, the possibility of exposure to
    environmental toxins has not been ruled out as yet either.

    More information from knowledgeable sources in the region would be
    greatly appreciated.

    For a map of the Neno district of Malawi, see
    <http://www.maplandia.com/malawi/southern/neno/>. For a map of the
    Tsangano district of Mozambique, see
    <http://www.maplandia.com/mozambique/tete/tsangano/>. If one zooms
    out, one sees that the 2 districts are to the south of Lake Nyasa.

    For the interactive HealthMap/ProMED map of Neno, Malawi, see
    <http://healthmap.org/r/00Aa>, and for Tsangano Mozambique, see
    <http://healthmap.org/r/00Ab>. - Mod.MPP]
    ..............................mpp/ejp/dk

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  • #2
    Re: Undiagnosed fatalities - 15 dead - Mozambique and Malawi - RFI

    We'll have to wait a few days for the diagnosis out of the reference laboratories in South Africa. There may be more than one illness at work here, which may be complicating the diagnosis.

    Comment


    • #3
      Outbreak of mystery illness in Mozambique (and Malawi)

      I thought I had posted the ProMed report below as undiagnosed fatalities on here somewhere, but the new report seems to give a possible diagnosis. Also of note in the new report is that the figures in the July 11th ProMed posting are as of July 3rd.



      Mozambique: Surveillance has been strengthened to the outbreak of the disease not yet identified which began on 24 June 2009 in the District Tsangano, Tete province which borders the district of Neno Malawi and seen as a viral meningo encephalitis . Au total 103 cas 14 d?c?s (l?talit?: 13,6%) ont ?t? notifi?s au 3 juillet 2009*. In total 103 cases 14 deaths (CFR 13.6%) were notified on 3 July 2009

      ----------------------------------------



      UNDIAGNOSED FATALITIES - MALAWI, MOZAMBIQUE: REQUEST FOR INFORMATION
      ************************************************** ******************
      A ProMED-mail post
      <http://www.promedmail.org>
      ProMED-mail is a program of the
      International Society for Infectious Diseases
      <http://www.isid.org>

      Date: 11 Jul 2009
      Source: Nation Online, Window on Malawi [edited]
      <http://www.nationmw.net/newsdetail.asp?article_id=3384>


      Strange disease hits Neno
      -------------------------
      An unknown disease has killed 15 people out of 103 patients since May
      this year [2009] in 2 bordering villages of Mtemankhawa and Datson in
      Malawi and Mozambique, respectively. Mtemankhawa Village, with a
      total population of 753, is in the area of TA Dambe in Neno while
      Datson Village, in the area of Chief Tsangano in Mozambique, has a
      population of 329.

      Traditional leaders in the area and Secretary for Health Chris
      Kang'ombe have confirmed the occurrence of the unknown disease and
      the deaths. "It is true that 15 people out of 103 cases have died so
      far. 8 are from the Malawi side while 7 from Mozambique side. 5 are
      admitted to Neno District Hospital," said Kang'ombe in an interview
      yesterday. He described the disease as "not well known".

      The PS said the ministry has already sent laboratory samples to South
      Africa for analysis. The symptoms of the disease, according to
      Kang'ombe, include stiff neck, dehydration, fever, headache, joint
      pain, discomfort in abdomen and loss of voice. He ruled out meningitis.

      While waiting for the results of the samples, he said, the ministry
      is treating some patients with antibiotics and has supplied the
      people with Chlorine because "they use unprotected wells for water."
      He said the area is "very cold" and some people are forced not to
      bathe for many days. He said some live together with animals in their
      round grass-thatched houses which have no windows. "These could be
      some contributing factors but it is yet to be seen," said Kang'ombe.
      He said the ministry has also set up a treatment camp in the area to
      handle minor cases.

      Group Village Headman Chakulembera, who oversees Mtemankhawa Village,
      said in an interview on Wednesday [8 Jul 2009] in Mwanza that those
      affected by the disease develop stiff jaws, neck and have abdominal
      pains. "It makes it difficult for them to eat," he said.
      Chakulembera, who was flanked by village headman Mtemankhawa and T/A
      Dambe's envoy MacDonald Chindimwe, said among those killed include 5
      pupils, 3 from Chawe Primary School.

      "On average, we have 3 or 4 deaths per week. People are worried about
      the development because they cannot work in their wheat and Irish
      potato gardens," said Chakulembera, who was supported by Mtemankhawa
      who said: "The latest death was on Monday this week, 6 Jul 2009."

      The group village headman said the disease has affected almost every
      family, with some having more than one patient. Chakulembera said
      some patients died at Neno District Hospital but the majority
      succumbed at their homes. "We are living in fear. When one is
      attacked, we know he or she is going to die," he said.

      Chakulembera said health officials from both Malawi and Mozambique
      have been visiting the area "frequently" to monitor the situation.
      "The Ministry of Health supplied us with Chlorine to add to the water
      we use," confirmed Chakulembera. There is no piped water or
      boreholes. Most of the houses are old round grass-thatched ones and
      have no windows. People sleep together with animals in such houses,"
      he said when asked to explain the living conditions of the people in
      the affected area.

      On another note, Mtemankhawa said he is living in fear for his life
      after some of his villagers warned they would "deal with him. They
      accuse me of being a wizard and that I am behind the deaths. They
      make such allegations because they say I do not provide a solution.
      But it is not true," he said.

      He said villagers have since agitated for a witchdoctor to come to
      the village to find the cause of the mysterious disease. He also said
      grave-diggers have threatened to abandon their work, arguing they are
      fed up with the frequent deaths. Dambe's advisor said the chief
      advised fellow traditional leaders to tell people to stop sleeping in
      the same house with animals and ensure that all dwelling units have
      windows and pit latrines as preventive measures.

      --
      Communicated by:
      ProMED-mail
      <promed@promedmail.org>

      [The above newswire describes a clinical picture that is difficult to
      come to diagnostic conclusions on. Some of the symptoms might lead
      one to think meningitis was the etiology, but the newswire mentions
      that meningitis has been ruled out. Other symptoms might be
      compatible with the more severe form of leptospirosis, although
      arthralgias are described rather than myalgias, and jaundice is not
      mentioned where it tends to be a predominant presenting symptom with
      severe leptospirosis. According to the article, since the beginning
      of May 2009, the overall attack rate has been 9.5 percent (103 cases
      out of a total population of 1082) with a case fatality rate of 14.6
      percent. Oftentimes when one reads newswires, the presumed risk
      factors of disease mentioned helps to narrow down the etiologic
      agent. In the above newswire this isn't really the case as it
      mentions poor water and sanitation, and close proximity to animals,
      risk factors for a large spectrum of microbial agents includi!
      ng bacterial and viral agents. Note, that while this moderator is
      mentioning microbial agents, the possibility of exposure to
      environmental toxins has not been ruled out as yet either.

      More information from knowledgeable sources in the region would be
      greatly appreciated.

      For a map of the Neno district of Malawi, see
      <http://www.maplandia.com/malawi/southern/neno/>. For a map of the
      Tsangano district of Mozambique, see
      <http://www.maplandia.com/mozambique/tete/tsangano/>. If one zooms
      out, one sees that the 2 districts are to the south of Lake Nyasa.

      For the interactive HealthMap/ProMED map of Neno, Malawi, see
      <http://healthmap.org/r/00Aa>, and for Tsangano Mozambique, see
      <http://healthmap.org/r/00Ab>. - Mod.MPP]
      ..............................mpp/ejp/dk

      Comment


      • #4
        Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

        This might be something unusual, as the US CDC is now getting involved. Also note the increase to 120 cases with 17 deaths.



        Malawi - United States - Health



        Des m&#233;decins am&#233;ricains au Malawi pour &#233;tudier une maladie myst&#233;rieuse American doctors in Malawi to investigate a mysterious disease

        APA-Lilongwe (Malawi) Le gouvernement am&#233;ricain a d&#233;p&#234;che cinq &#233;pid&#233;miologistes du Centre de lute contre les maladies (CDC) bas&#233; &#224; Atlanta, &#224; Neno, une localit&#233; situ&#233;e dans le sud du Malawi pour enqu&#234;ter sur l'apparition d'une maladie inconnue qui vient de se signaler. APA-Lilongwe (Malawi) The U.S. government has sent out five epidemiologists CENTRAL fight against the disease (CDC) based in Atlanta, Neno, a city located in southern Malawi to investigate the occurrence of a disease unknown has just been reported.

        Selon un officiel am&#233;ricain, &#171; Le groupe va commencer son travail avec le responsable de sant&#233; du District dans les localit&#233;s concern&#233;es afin de mener une enqu&#234;te compl&#232;te sur l'apparition et rendre compte au ministre de la sant&#233; &#187;. According to a U.S. official, "The group will begin its work with the head of Health District in the localities concerned to conduct a full investigation into the outbreak and report to the minister of health."

        Depuis le mois de mai, une maladie myst&#233;rieuse a touch&#233; plus de 90 personnes &#224; Neno et plus de 30 autres dans la localit&#233; voisine de Tsangano au Mozambique,avec un bilan de 17 morts souligne t-on. Since May, a mysterious disease has affected over 90 people in Neno and over 30 others in the nearby town of Tsangano in Mozambique, with a balance of 17 dead stresses there.

        Les personnes touch&#233;es par cette maladie pr&#233;sentent des complications neurologiques. Those affected by this disease have neurological complications. Les essais de laboratoire et de radiologie pr&#233;liminaires n'ont indiqu&#233; aucune maladie sp&#233;cifique. Laboratory tests and preliminary X-ray indicated no specific disease.

        Comment


        • #5
          Re: US sends five outbreak specialists to investigate Malawi mysterious outbreak

          US sends five outbreak specialists to investigate Malawi mysterious outbreak
          Published July 24th, 2009 in World News, Africa News.
          from Charles Mkula 5:32 am
          date Jul 23, 2009 5:32 AM
          subject US sends five outbreak specialists to investigate Malawi mysterious outbreak

          US sends five outbreak specialists to investigate Malawi mysterious outbreak

          By Charles Mkula

          Lilongwe. The United States Government, through the Centers for
          Disease Control (CDC), flown into Malawi five outbreak specialists to
          work in Neno District, where an undiagnosed disease outbreak which has
          so far killed 17 people since May.

          Alison Liwanda, US Embassy Information Assistant said the specialists
          are experts in environmental health and neurology and are working with
          the Neno District Health Office to conduct a full investigation on the
          outbreak.

          The disease has affected 95 persons in the district in Malawi and 38
          in neighbouring Tsangano District in Mozambique. Of the 17 deaths
          reported nine have occured in Malawi, and eight in Mozambique.

          According to eye witnesses, affected persons display unusual symptoms
          with neurological complications. Patients admitted to hospital have
          been treated with antibiotics and given supportive care including
          rehydration.

          The Malawi government earlier in the month sent blood samples for
          initial laboratory and radiology examinations to South Africa, and
          Zimbabwe but the results were not indicative of any specific illness.

          New samples have now been sent to the Centers for Disease Control and
          Prevention (CDC) in the USA for analysis, said Liwanda.

          The Government of Malawi formally requested Epidemiological Aid
          assistance from United States Government on July 15. Typically, the
          CDC?s official response includes specialists in the relevant health
          fields working with host country health officials to deal with
          epidemiological investigation, diagnosis and laboratory support,
          treatment and containment of the outbreak. The CDC works
          collaboratively with the World Health Organization (WHO) and other
          partners in country.


          --------------------------------------------------------------------------------

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          • #6
            Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

            If the US CDC is involved we should get a diagnosis really soon. Hopefully this should help to tell what some of the other outreaks are.

            Comment


            • #7
              Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

              And this article quotes 133 cases with 17 deaths.



              Neno outbreak affects 133
              BY THERESA KASAWALA
              12:48:37 - 24 July 2009

              The mysterious epidemic that has plagued Neno continues to cause casualties. It has now infected 133 people and caused 17 deaths.

              A press statement from the United States Government says the disease, which broke out in May this year, has infected 95 people in Neno and 38 in neighbouring Tsangano district in Mozambique.

              ?Affected persons display unusual symptoms with neurological complications. Patients admitted to the hospital have been treated with antibiotics and given supportive care including rehydration,? the statement states.

              The development forced the Malawi government to seek help from the US government which has sent five specialists to investigate the outbreak.

              ?The specialists have expertise in environmental health and neurology. They arrived in the country on July 20, and are working with the District Health Officer and his team to conduct a full investigation on the outbreak,? the statement says.

              It states that the experts were conducting epidemiological investigations, diagnosis and laboratory support, treatment and containment of the outbreak.

              ?Previous attempts to demystify the disease have proved futile because the blood samples collected by the ministry for testing in Malawi, Zimbabwe and South Africa all yielded negative,? says part of the statement.

              According to the statement, new samples have been taken and are being shipped to the Centers for Disease Control and Prevention (CDC) in the USA for further analysis.

              Secretary for Health Chris Kang?ombe confirmed in an interview yesterday that the specialists have already started their work.

              Kang?ombe said the specialists would be in the country for two to three weeks.

              ?The results will be available immediately they finish their mission in the country,? the PS said.

              The Government of Malawi formally requested Epidemiological Aid assistance from United States Government on July 15.

              Comment


              • #8
                Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

                Originally posted by Rwilmer View Post
                If the US CDC is involved we should get a diagnosis really soon. Hopefully this should help to tell what some of the other outreaks are.
                It might, or might not. I think there is a good chance that this one is going to be a novel encephalitis virus, possibly either waterborne or vector-borne. It is also possible that this one might not be infectious at all but could be exposure to some toxin. The rate of new cases has remained fairly steady, neither increasing or decreasing over the past couple weeks. That suggests an ongoing exposure.

                Comment


                • #9
                  Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

                  Originally posted by alert View Post
                  It might, or might not. I think there is a good chance that this one is going to be a novel encephalitis virus, possibly either waterborne or vector-borne. It is also possible that this one might not be infectious at all but could be exposure to some toxin. The rate of new cases has remained fairly steady, neither increasing or decreasing over the past couple weeks. That suggests an ongoing exposure.
                  So would an ongoing exposure, indicate that this is waterboune or vector bourne and cannot spread from person to person?

                  Comment


                  • #10
                    Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

                    Originally posted by Rwilmer View Post
                    So would an ongoing exposure, indicate that this is waterboune or vector bourne and cannot spread from person to person?
                    I'm leaning that way on this outbreak. The timing doesn't seem like person-to-person. But I don't know for sure. That attack rate is very high. The total population of the two villages is less than 1100 people, so you are now approaching a 15&#37; attack rate. This outbreak seems very odd. The symptoms are bizarre and varied, and the fact that the South African labs couldn't find anything is odd. We learned last year that they could find even a novel virus quickly. But they didn't find anything here.

                    I do agree with you though, that the CDC's involvement makes this one the most likely of the undiagnosed neurological illnesses to get diagnosed.

                    Comment


                    • #11
                      Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

                      If anyone can diagnose it is the US CDC. They found swine flu.

                      Comment


                      • #12
                        Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

                        And ProMed strikes again on this one. I strongly agree with the bold statement. If there were an infectious agent, the South Africa labs would have found it. Also, the fact that the outbreak has been continuing for two months with new cases, but no geographical spread is not really consistent with an infectious agent.



                        UNDIAGNOSED FATALITIES - MALAWI, MOZAMBIQUE (02): REQUEST FOR INFORMATION
                        ************************************************** ***********************
                        A ProMED-mail post
                        <http://www.promedmail.org>
                        ProMED-mail is a program of the
                        International Society for Infectious Diseases
                        <http://www.isid.org>

                        Date: 24 Jul 2009
                        Source: Daily Times, Malawi
                        <http://www.dailytimes.bppmw.com/article.asp?ArticleID=13893>


                        Neno outbreak affects 133
                        -----------------
                        The mysterious epidemic that has plagued Neno continues to cause
                        casualties. It has now infected 133 people and caused 17 deaths.

                        A press statement from the United States Government says the disease,
                        which broke out in May this year [2009], has infected 95 people in
                        Neno and 38 in neighbouring Tsangano district in Mozambique.

                        "Affected persons display unusual symptoms with neurological
                        complications. Patients admitted to the hospital have been treated
                        with antibiotics and given supportive care including rehydration,"
                        the statement states.

                        The development forced the Malawi government to seek help from the US
                        government which has sent 5 specialists to investigate the outbreak.

                        "The specialists have expertise in environmental health and
                        neurology. They arrived in the country on [20 Jul 2009], and are
                        working with the District Health Officer and his team to conduct a
                        full investigation on the outbreak," the statement says.

                        It states that the experts were conducting epidemiological
                        investigations, diagnosis and laboratory support, treatment and
                        containment of the outbreak.

                        "Previous attempts to demystify the disease have proved futile
                        because the blood samples collected by the ministry for testing in
                        Malawi, Zimbabwe and South Africa all yielded negative," says part of
                        the statement.

                        According to the statement, new samples have been taken and are being
                        shipped to the Centers for Disease Control and Prevention (CDC) in
                        the USA for further analysis.

                        Secretary for Health Chris Kang'ombe confirmed in an interview
                        yesterday that the specialists have already started their work.

                        Kang'ombe said the specialists would be in the country for 2 to 3 weeks.

                        "The results will be available immediately they finish their mission
                        in the country," the PS said.

                        The Government of Malawi formally requested Epidemiological Aid
                        assistance from United States Government on [15 Jul 2009].

                        [Byline: Theresa Kasawala]

                        --
                        Communicated by:
                        ProMED-mail <promed@promedmail.org>

                        [There are now 133 cases and 17 deaths (case fatality rate [CFR] 12.8
                        percent). In the 1st newswire covered in a prior ProMED-mail posting
                        on 11 Jul 2009 (see archive number 20090711.2489), there were
                        reports of 103 cases with 15 deaths (CFR 14.6 percent). The earlier
                        report mentioned a total population at risk of 1082, so the overall
                        attack rate has increased from 9.5 percent to 12.3 percent. The
                        earlier report mentioned a symptom complex of "stiff neck,
                        dehydration, fever, headache, joint pain, discomfort in abdomen and
                        loss of voice". The above newswire doesn't provide much more on the
                        clinical picture other than to mention neurologic complications. The
                        mention that environmental health specialists and neurologists are on
                        the investigating team from the CDC in the USA suggests that
                        environmental etiologies are suspected.


                        More information on this outbreak from knowledgeable sources would be
                        greatly appreciated.

                        For a map of the Neno district of Malawi, see
                        <http://www.maplandia.com/malawi/southern/neno/>. For a map of the
                        Tsangano district of Mozambique, see
                        <http://www.maplandia.com/mozambique/tete/tsangano/>. If one zooms
                        out, one sees that the 2 districts are to the south of Lake Nyasa.

                        For the interactive HealthMap/ProMED map of Neno, Malawi, see
                        <http://healthmap.org/r/00Aa>, and for Tsangano Mozambique, see
                        <http://healthmap.org/r/00Ab>. - Mod.MPP]

                        Comment


                        • #13
                          Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

                          Note the increase to 19 deaths. The mention of a virus here is purely speculative; we have no idea what is causing this outbreak. The CDC ought to be able to give us some results soon. At the very least, they should be able to tell whether person-to-person spread is occurring, or whether the cases are sporadic.




                          US medical experts in Malawi to investigate bizarre virus
                          By David .Five American medical experts are in Malawi to conduct full investigations on a strange disease that has so far claimed lives of over 15 people in Neno district and the neighbouring Mozambique.


                          The five environmental health and neurology experts arrived in the country on July 20 and have already conducted a full investigation on the outbreak.

                          The United States (US) Embassy Office in Lilongwe said the specialists were brought into the country through the Centre for Disease Control (DCD) in response to a request from the Malawi Government for an intervention on the matter.

                          An undiagnosed disease broke out in Neno some three months ago and so far about 10 Malawians and nine Mozambicans have died after being attacked by the strange disease.

                          And close to 100 people in Neno district and about 40 in Tsangano district in Mozambique have so far been affected since the disease was first reported in May this year.

                          Affected people display unusual symptoms with neurological complications. However, patients with such symptoms have been treated with antibiotics and given supportive care including rehydration.

                          Initial laboratory and radiology examinations have not indicated any specific illness but the American experts have collected new samples which have been shipped to the Centers for Disease Control and Prevention (CDC) in the USA for analysis.

                          The Ministry of Health collected blood samples for further testing in Malawi, Zimbabwe and South Africa, whose results were negative.

                          “The CDC’s official response includes specialists in the relevant health fields working with host country health officials to deal with epidemiological investigation, diagnosis and laboratory support, treatment and containment of the outbreak,” says a media statement from the US Embassy.

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                          • #14
                            Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

                            This might just be an echo story, especially since it only mentions 18 deaths and we had a story a couple weeks ago that mentioned 19. Also, it mentions that the samples have been sent to South Africa. Those samples came back empty weeks ago. The CDC has now had a team in the area since July 20, and still they haven't found anything. This is likely to be VERY unusual. I don't even think a novel virus would be unusual enough - the South African labs and CDC would have found that by now.

                            I don't know if orally (and the same word in Spanish) means foodborne or what we would call fecal-oral.



                            18 people die on the border of Mozambique and Malawi
                            Internacional - Jueves 6 de agosto (08:40 hrs.) International - Thursday, August 6 (08:40 hrs.)




                            Fallecen a causa de una enfermedad desconocida Die from an unknown disease
                            Al parecer se transmite por v&#237;a oral Apparently transmitted orally


                            El Financiero en l&#237;nea El Financiero Online

                            Maputo, 6 de agosto.- Dieciocho personas han muerto v&#237;ctimas de una enfermedad desconocida en la frontera de Mozambique y Malaui, inform&#243; hoy el peri&#243;dico mozambique&#241;o "O Pa&#237;s". Maputo, August 6 .- Eighteen people have died of an unknown disease at the border of Malawi and Mozambique, Mozambican newspaper reported today "O Pais".

                            Seg&#250;n el rotativo, que cita fuentes m&#233;dicas, los hospitales de la zona est&#225;n a la espera de recibir los resultados de los an&#225;lisis que est&#225;n siendo efectuados en Sud&#225;frica. According to the newspaper, citing medical sources, hospitals in the area are awaiting the results of the analysis being carried out in South Africa.

                            "La &#250;ltima v&#237;ctima mortal se produjo en las &#250;ltimas 48 horas en el hospital del distrito de Neno, en Malawi", donde adem&#225;s est&#225;n ingresados varios pacientes mozambique&#241;os, informa el diario. "The last fatality occurred in the last 48 hours in Neno District Hospital in Malawi, where many patients are also admitted Mozambicans, the newspaper reported.

                            Las autoridades, que pronostican que la enfermedad se transmite por v&#237;a oral, han confirmado que la dolencia afecta al sistema nervioso central, que causa p&#233;rdidas de voz y dolores abdominales, y que sus s&#237;ntomas pueden confundirse con los de la malaria. The authorities predict that the disease is transmitted orally, have confirmed that the disease affects the central nervous system, causing loss of voice and abdominal pain, and symptoms can be confused with those of malaria.

                            Carla Mosse, m&#233;dico de la provincia de Tsangano, dijo que podr&#237;a ser una dolencia causada por las bajas temperaturas que se registran en esa zona del pa&#237;s. Carla Mosse, medical Tsangano province, said a condition could be caused by the low temperatures recorded in that region. (Con informaci&#243;n de EFE/CFE) (With information from Reuters / CFE)

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                            • #15
                              Re: Outbreak of meningitis/encephalitis in Mozambique (and Malawi)

                              So now we are up to 142 cases with 20 deaths. The CDC has been investigating this for over a month, and still hasn't found anything. It does appear that there have only been about 9 news cases in the past month.

                              An outbreak of a strange disease in the district of Tsangano, in the central Mozambican province of Tete, has killed at least 20 people since it was first reported last May.


                              Mozambique: Mysterious Disease Kills 20 in Tete
                              16 August 2009

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                              Maputo — An outbreak of a strange disease in the district of Tsangano, in the central Mozambican province of Tete, has killed at least 20 people since it was first reported last May.

                              At present there some 142 infected, reported Mozambique's state television TVM on Saturday.

                              The health authorities in Tete are concerned with the outbreak of this disease, since it is still unclear its real source.

                              According to the health authorities, they are still waiting for laboratory results of the samples sent to the neighbouring South Africa

                              The disease attacks the central nervous system. In the early the stages its symptoms are similar to malaria, including abdominal pain, and loss of voice in its advanced stages.

                              As the origin of the disease is still unknown, the team of doctors both national and foreign working in the region are just prescribing antibiotics to the patients.

                              Meanwhile, the health authorities, in partnership with other relevant entities, including community leaders, have already launched a sanitation campaign in the affected communities.

                              There is a suspicion that the disease may have its origin in the region of Maujete, district of Tsangano, in the province of Tete, which still lacks a health centre.

                              Some of the patients have been taken to a district hospital in Neno, in neighbouring Malawi, for treatment.

                              The province of Tete shares the same border with Malawi.

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