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  • Overuse of antibiotics leaves children open to infection

    Overuse of antibiotics leaves children open to infection

    DR. MARLA SHAPIRO
    As the weather gets colder, we know that the inevitable season of colds and flu illnesses in our kids is likely to peak. With close crowding, shared toys and overheated environments, it is easy for germs to spread from one child to another. Along with those infectious diseases comes a visit to your doctor or walk-in clinic. All too often, an antibiotic is prescribed when it might not be required.

    <!-- /Summary -->The overuse and inappropriate use of antibiotics has led to antibiotic resistance, prompting agencies such as the U.S. Centers for Disease Control and Prevention to call the situation one of the "world's most pressing public health problems."

    Because of the widespread and inappropriate use of these medications, we have seen the rampant increase of bacteria that have become immune to the most common antibiotics that we prescribe to fight infections. When an antibiotic is used unnecessarily, the germs learn how to become resistant to it, rendering the drugs useless against them. Of particular concern is the pediatric population. Kids have the highest rate of antibiotic use. And, not surprisingly, they also have the highest rate of illnesses that are caused by these resistant bugs.

    A recent study in the British Medical Journal highlighted that antibiotics should not be given to a patient with runny nose and coloured discharge. When nasal discharge is green, it often acts as a catalyst for the doctor to prescribe an antibiotic. (Many doctors think that a green or yellow nasal discharge is a sign of a bacterial infection. But this is not necessarily the case.) The study showed that for every seven patients who get antibiotics in this clinical situation, six will not receive any benefit at all.
    Even worse, some studies show that for every 15 patients treated, 14 will get no benefit and only one will be improved by the use of antibiotics. Possible side effects of antibiotics can include vomiting, diarrhea, stomach upset, rashes and even hyperactivity. The study found that most patients will get better without the prescription medication.

    A recent study in the September issue of the Journal of the American Medical Association looked at a different way of dealing with ear infections called the "WASP" approach -- which stands for "wait-and-see prescription." Ear infections, also known as otitis media, represent the most common acute infectious illness for which doctors offer antibiotic treatment.

    In the study, 283 children with acute ear infections between the ages of six months and 12 years of age were randomly assigned to one of two treatment groups. One group received the standard antibiotic therapy while the other half were given the wait-and-see prescription and told only to fill it if the child got steadily worse.

    All children in both treatment groups got ibuprofen and ear drops to use at home for pain management if needed. The study found that for patients in the WASP group, 62 per cent did not fill the prescription. In the standard treatment group, just 13 per cent did not fill the prescription.

    Yet there was no real difference between the groups when it came to subsequent fever, ear ache or unscheduled visits for medical care.

    The study showed that the wait-and-see approach significantly decreased the use of antibiotics, reducing the risk of antibiotic resistance. While it is critical to treat those children at risk for worsening outcomes, it is reasonable to consider delaying the use of an antibiotic when the child is not terribly ill or the prescribing physician feels it is reasonable to adopt this approach. For infants younger than six months, or for those who appear sicker, antibiotics might be used without waiting.

    It is important to remember that antibiotics aren't useful in treating viral infections.

    They're not required for colds, flu, chest cold in otherwise healthy children and adults, sore throats (with the exception of those caused by strep bacteria), many cases of bronchitis in otherwise healthy adults and children, and many ear infections.

    If your doctor does not feel an antibiotic is required, do not demand it -- it will not help treat the infection or make you feel better faster. If you are given an antibiotic, remember to take all the doses. Don't save any for "the next time" and never take anyone else's prescription antibiotics.
    Have a conversation with your physician about what signs to look out for that might indicate an infection is getting worse and might need a medication to bring it under control.

    For example, with a chest infection that causes wheezing, an inhaler might be used. You should also be given clear information about when reassessment is required.

    Together, by using medication in an appropriate fashion, we will all benefit as a community and decrease antibiotic resistance.

  • #2
    Re: Overuse of antibiotics leaves children open to infection

    This following link is on MSN home page. You might find this interesting relative to the above information:

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    • #3
      Re: Overuse of antibiotics leaves children open to infection

      All thanks to gjs47


      Flu Drug Tamiflu May Cause Odd Behavior in Children



      SOURCES: Marc Siegel, M.D., clinical associate professor of medicine, New York University School of Medicine, New York City, author, Bird Flu: Everything You Need to Know About the Next Pandemic; Nov. 13, 2006, press conference with Julie Gerberding, M.D., director, U.S. Centers for Disease Control and Prevention, Atlanta; John Agwunobi, M.D., assistant secretary for health, U.S. Department of Health and Human Services, Washington, D.C.; L. J. Tan, M.D., American Medical Association, Chicago; Nov. 13, 2006, Archives of Internal Medicine; Associated Press


      <hr class="dashedHr">Meanwhile, CDC calls flu vaccine plentiful, despite some delays in shipments
      By Steven Reinberg, HealthDay Reporter


      <table class="ImgBull" align="left" border="0" cellpadding="0" cellspacing="0" width="120"><tbody><tr><td style="padding-bottom: 10px;" valign="top"></td></tr><tr><td valign="top">More on this in Health & Fitness

      </td></tr></tbody></table>MONDAY, Nov. 13 (HealthDay News) -- Responding to reports from overseas, U.S. heath officials are urging doctors and parents to watch for signs of bizarre behavior in children taking the flu drug Tamiflu.
      Officials at the U.S. Food and Drug Administration don't know if the more than 100 new cases of strange behavior, including three deaths from falls, are tied to the drug, to the flu itself, or a combination of both, the Associated Press reported.


      The FDA is mulling changes to the Tamiflu label that may recommend that all patients, especially children, be closely monitored while on the drug.


      The agency acknowledged that stopping Tamiflu treatment might harm flu patients if the virus is the underlying cause of delirium, hallucinations and other abnormal behavior that make up the symptoms observed in children abroad. Many of the pediatric problems have been reported in Japan, where the number of Tamiflu prescriptions is about 10 times greater than in the United States, the AP said.


      Although severe cases of flu have been known to produce such side effects, the number and type of cases, plus comments from doctors who believe the abnormal behavior is associated with the drug, are keeping the FDA from ruling out Tamiflu as the cause.
      The FDA's pediatric advisory committee is to discuss the label recommendation on Thursday, the AP said. The FDA typically follows the advice of its advisory panels.


      Also on Monday, the U.S. Centers for Control and Prevention said that, despite delays in the distribution of seasonal flu vaccine this year, the agency is confident that enough doses of vaccine will be available over the next few weeks to meet any demand.
      In October, the CDC said that while there was no shortage of vaccine this year, there were going to be delays in getting all the doses manufactured and distributed. The problem particularly affects children's doses.


      Since these are delays, not shortages, CDC Director Dr. Julie Gerberding said she's encouraging people to get vaccinated even as late as early January.


      "It's the beginning of the flu season," Gerberding said during a teleconference. "As always, flu is unpredictable, so we are not going to be able to say how fast it's going to evolve, where it will hit next, or how bad it will be."


      Cases of flu have already been reported in Arizona and California. Usually, the flu season peaks in late January or February.


      Gerberding noted that this year's supply of vaccine is the largest ever produced in the United States. "We are still projecting between 110 million and 115 million doses," she said. So far, about 77 million doses have been distributed.


      In all, 210 million Americans are eligible for flu shots, Gerberding said, including children between 6 months and 5 years of age.


      Although the total number of vaccine doses is the largest ever, there are areas of the country experiencing shortages. "There are certain providers and health agencies that are having trouble getting their doses," Gerberding said. "There are still mismatches between the need and the supply."


      Gerberding noted that these delays are out of the CDC's hands. "These are private-sector problems," she said.


      The CDC is participating in a national influenza vaccine drive to encourage people to get vaccinated whenever vaccine is available. "It is never too late to get your flu shot," Gerberding said. Moreover, getting vaccinated is the best way to protect yourself from the flu, she added.

      <table class="tableStylesPreserved" cellpadding="5"><tbody><tr><td class="textBodyBlack" colspan="1" rowspan="1" valign="top"></td><td class="textBodyBlack" colspan="1" rowspan="1" valign="top">Read More on MSN Health & Fitness:
      Cold and Flu:Immunizations:</td></tr></tbody></table>
      At the teleconference, Dr. John Agwunobi, assistant secretary for health at the U.S. Department of Health and Human Services, said people could get vaccinated as late as early January.


      Dr. L.J. Tan, a spokesman for the American Medical Association, said, "We know that there are substantial medical benefits to receiving the vaccine after Thanksgiving and beyond. It is often mistakenly believed that the only time to get the vaccine is before Thanksgiving."


      Gerberding acknowledged that many parents are concerned about the addition of thimerosal to the flu vaccine. Thimerosal, a mercury compound used as a preservative, is suspected by some be at least partly responsible for the growing number of autism cases among children.


      "Children can have very serious disease from influenza," Gerberding said. "The flu shot is the best way to protect them, there's no doubt about that.
      Concerns about thimerosal are on the minds of many parents. We have not been able to identify any data that indicates a flu shot poses any risk associated with thimerosal."


      The CDC chief believes the benefits of vaccination are too important to ignore. "If you are balancing the benefit of immunization with what is an unknown or no-risk situation from thimerosal, it seems clear to me what needs to be done," Gerberding said. "That's why we in the public-health community are encouraging parents to get their kids vaccinated. The risk of flu far outweighs any theoretical complications from the vaccine."


      In related news, a study in the Nov. 13 issue of the Archives of Internal Medicine finds that the flu vaccine slightly increases the risk of Guillain-Barre syndrome, which occurs when the body's immune system attacks part of the nervous system, resulting in tingling or weakness and possible paralysis.


      "This study has findings that are consistent with findings that were published a few years ago," Gerberding said. "These findings indicate that there is an increased risk of about one in a million of Guillain-Barre syndrome cases among those who are vaccinated, compared to those who are not vaccinated. But when we compare the risks associated with influenza infection with the risk of Guillain-Barre syndrome, we see that the risk of not being vaccinated far outweighs the risk for Guillain-Barre syndrome," she said.


      One expert thinks the flu vaccine is safe and effective, and that thimerosal is not really a problem, compared with the potential consequences of flu.
      "We have environmental concerns, but to put it all on thimerosal based on an unproven association is really the wrong way to go," said Dr. Marc Siegel, a clinical associate professor of medicine at New York University School of Medicine, and author of Bird Flu: Everything You Need to Know About the Next Pandemic. "I am satisfied that there has never been an association shown between thimerosal and autism."


      Each year in the United States, as much as 20 percent of the population can get the flu, more than 200,000 people are hospitalized from flu complications, and about 36,000 people die from the disease, according to the CDC.


      More information
      For more on the flu and flu vaccines, visit the CDC.
      content by:

      SOURCES: Marc Siegel, M.D., clinical associate professor of medicine, New York University School of Medicine, New York City, author, Bird Flu: Everything You Need to Know About the Next Pandemic; Nov. 13, 2006, press conference with Julie Gerberding, M.D., director, U.S. Centers for Disease Control and Prevention, Atlanta; John Agwunobi, M.D., assistant secretary for health, U.S. Department of Health and Human Services, Washington, D.C.; L. J. Tan, M.D., American Medical Association, Chicago; Nov. 13, 2006, Archives of Internal Medicine; Associated Press

      Comment


      • #4
        Re: Overuse of antibiotics leaves children open to infection

        The overuse and inappropriate use of antibiotics has led to antibiotic resistance, prompting agencies such as the U.S. Centers for Disease Control and Prevention to call the situation one of the "world's most pressing public health problems."
        TRUE, can to say MRSA?

        It is important to remember that antibiotics aren't useful in treating viral infections.
        BUT, severe viral infections lead to secondary bacterial infections, particularly of the respiratory tract....remember 1918-9?
        21st Century Omega Man

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