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6-yr-old vaccinated for varicella gets unusual case of Ramsey-Hunt (Shingles) from wild-type varicella

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  • 6-yr-old vaccinated for varicella gets unusual case of Ramsey-Hunt (Shingles) from wild-type varicella

    http://www.ncbi.nlm.nih.gov/pubmed/22352034
    No To Hattatsu. 2012 Jan;44(1):66-8.
    [Case of atypical Ramsay-Hunt syndrome who presented with severe vertigo and vomiting].
    [Article in Japanese]
    Nakamura Y, Matsumoto H.
    Source

    Department of Pediatrics, National Defense Medical College Hospital, Tokorozawa, Saitama.
    Abstract

    We herein present a case of 6-year-old female demonstrating atypical Ramsay-Hunt syndrome. She presented with an earache, severe vertigo, and vomiting at onset, and thereafter, herpes zoster oticus appeared. No facial nerve palsy was seen. She was vaccinated for varicella and had no past history of apparent varicella infection. The patient showed positive IgG and negative IgM serum antibodies for varicella-zoster virus (VZV). An analysis of VZV-DNA from the patient's ear lesion using alleric discrimination real-time PCR identified a wild-type strain of VZV. We diagnosed her to have atypical Ramsay-Hunt syndrome caused by reactivation of the VZV. Aciclovir and prednisolone were administered, and she recovered completely. This case indicates that Ramsay-Hunt syndrome could be caused by a VZV infection after vaccination, even though its frequency is low. Ramsay-Hunt syndrome may thus be considered as one of causes of sudden onset vertigo in children.

    PMID:
    22352034
    [PubMed - indexed for MEDLINE]
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