Korea Suspected Human avian influenza case

[Giuseppe]

Re: Korea-Suspected Human AI case

About the NINE people serologically tested H5N1 positive:

(...)
South Korea has never reported any human H5N1 cases or deaths, but in September 2006 health officials said five workers who helped cull poultry during outbreaks in 2003 had antibodies to the H5N1 virus but had never had symptoms.

The 2006 report brought the total number of South Korean poultry workers who tested positive for H5N1 antibodies to nine.

Tests on the workers' samples were done at the US Centers for Disease Control and Prevention.
(...)

SOURCE: CIDRAP, http://www.cidrap.umn.edu/cidrap/con...ulling(2).html

[Treyfish]

Re: Korea-Suspected Human AI case

<TABLE id=tbl_article cellSpacing=0 cellPadding=0 width="100%" border=0><TBODY><TR><TD style="PADDING-BOTTOM: 20px"><TABLE cellSpacing=0 cellPadding=0 border=0><TBODY><TR><TD>Authorities detect H5 case in Korean soldier
</TD></TR></TBODY></TABLE>

April 23, 2008

</TD></TR><TR><TD class=actxt id=articleBody style="PADDING-RIGHT: 0px; PADDING-LEFT: 0px; FONT-SIZE: 18px; PADDING-BOTTOM: 20px; LINE-HEIGHT: 27px; PADDING-TOP: 0px">A 22-year-old soldier, quarantined since Sunday, is suspected of having been infected with a form of avian influenza virus, but did not develop symptoms, authorities said yesterday.
Tests have shown that the virus detected in the patient??s body was an H5 strain, according to the Korea Center for Disease Control and Prevention. It will take up to three weeks for a lab to confirm whether or not the strain is the deadly H5N1 strain, which has caused massive outbreaks in the Jeolla region since April 1.
The young corporal, identified only by his family name Cho, was sent to help kill infected chickens and ducks on Friday and Saturday. He suffered from high fever and was transported to an army hospital Sunday.
Authorities said his sickness was not related to the bird flu and that his condition has improved.
According to the World Health Organization, only four out of hundreds of strains of avian influenza viruses are known to have caused human infections ? H5N1, H7N3, H7N7 and H9N2.
??In general, human infection with these viruses has resulted in mild symptoms and very little severe illness, with one notable exception: the highly pathogenic H5N1 virus,?? according to the WHO. There have been is no confirmed human cases in Korea of H5N1.
??Following the initial examination of Cho, a small amount of H5 virus was detected,?? CDCP head Lee Jong-ku said in a media briefing at the Health Ministry yesterday. ??Since his condition is normal now, we believe that the virus did not cause serious harm.??
Cho had shown high fever and coughing even before his unit was assigned to the poultry slaughter mission last week, Lee said. He added that bacteria caused the soldier??s illness.
Dr. Park Seung-cheol of Samsung Medical Center, who had examined Cho, said the patient suffered from respiratory complications and high fever.
??I concluded that the symptoms were not caused by an avian influenza virus infection, ?? he said.
The Defense Ministry said all soldiers were withdrawn from the slaughter sites as of 3 p.m. yesterday.
Also yesterday North Korea said it will ban South Korean poultry and eggs from an inter-Korean industrial zone, according to the Unification Ministry.
The North informed the South that the move will take effect Saturday.
</TD></TR></TBODY></TABLE>

http://joongangdaily.joins.com/article/view.asp?aid=2888993

[Treyfish]

Re: Korea-Suspected Human AI case

AI first three suspected cases judwi final verification through inspection
Corporal Jo, high fever, respiratory disorders Sunchang jiyeokseo salcheobun jakeopdwi

Edit: 9:18:19 PM 2008-04-22



Gobyeongwonseong avian influenza (AI) occurred in the domestic poultry salcheobun soldier at the scene, which was first put in doubt AI isolates as a treatment for patients in 22 metropolitan jeonbukdo additional cases of human infection was suspected, said.
Countermeasures Headquarters defenses jeonbukdo AI and the AI is balbyeonghan jeongeup Kimje, Sunchang salcheobun beyond the participants and their farm workers, including 7,541 people defenses agents to conduct clinical observations and surveys, but the suspected patients are infected with the human body, said it did not occur .

.

However, the measures defenses Sunchang regional headquarters participating salcheobunjakeope respiratory disorders after being treated in hospital, and army commando brigade Corporal Jo is a member of WHO (World Health Organization) regulations' AI suspected patients' will be included.
WHO headquarters in the regulation defenses measures △ △ AI salcheobunjakeop participate in more than 38 ℃ fever symptoms such as cough △ severe respiratory failure in all the three requirements that the person is' AI suspected patients' states, he added.

있다.

Countermeasures Headquarters defenses salcheobunjakeop participants' gowiheomgun '' probation subjects' 'suspected patients'' hwakjinhwanja 'probation and step bunryuhae management.
Participants in the 7541 people power gowiheomgun Tokyo salcheobun included 206 subjects were observed and drew blood infection still doubt whether the patient did not include me out Corporal Joe unique.
Corporal Joe three weeks whether the AI virus infection through final tests confirm cultivation.

했다.

Defenses of the National Science and Countermeasures Headquarters on July 22, and yongdong Iksan geomyeokwon This material yeosanmyeon each poultry farm in 1 'H5' brother balhime AI virus has been detected on a farm, according to the remaining 61,000 chickens on the farm salcheobunhago lockdown decided.

한편 익산은 도내 최대 양계단지여서 고병원성 AI 발병이 확진될 경우 파장이 클 것으로 우려되고 있다.

Meanwhile, the Tokyo Iksan largest poultry hwakjindoel this case just because the wavelength is large gobyeongwonseong AI outbreaks are feared. http://209.85.135.104/translate_c?hl...6dt%3D20080423

[Laidback Al]

Re: Korea-Suspected Human AI case

About the NINE people serologically tested H5N1 positive:

(...)
South Korea has never reported any human H5N1 cases or deaths, but in September 2006 health officials said five workers who helped cull poultry during outbreaks in 2003 had antibodies to the H5N1 virus but had never had symptoms.

The 2006 report brought the total number of South Korean poultry workers who tested positive for H5N1 antibodies to nine.

Tests on the workers' samples were done at the US Centers for Disease Control and Prevention.
(...)

SOURCE: CIDRAP, http://www.cidrap.umn.edu/cidrap/con...ulling(2).html

A discussion thread on poultry culler infections in South Korea.

http://www.flutrackers.com/forum/showpost.php?p=58534&postcount=1

Subforums on past H5N1 outbreaks in South Korea.

http://www.flutrackers.com/forum/forumdisplay.php?f=370

[Giuseppe]

Re: Korea-Suspected Human AI case

AI first three suspected cases judwi final verification through inspection
Corporal Jo, high fever, respiratory disorders Sunchang jiyeokseo salcheobun jakeopdwi

In summary, the corporal has:
-- clinical presentation compatible with WHO case definition for H5N1 human infection (...Corporal Jo is a member of WHO (World Health Organization) regulations' AI suspected patients' will be included...; post #33); and
-- preliminary tests results detected H5 genetic material in samples; (...Following the initial examination of Cho, a small amount of H5 virus was detected...; post #32);
-- a bacterial super-infection.

No data about mode of exposure, adherence to PPE wearing, and no details on treatments and current health status. Also, the soldier chemoprophylaxis status not mentioned at this point. No data about seasonal human vaccination.

[HenryN]

Re: Korea-Suspected Human AI case

In summary, the corporal has:
-- clinical presentation compatible with WHO case definition for H5N1 human infection (...Corporal Jo is a member of WHO (World Health Organization) regulations' AI suspected patients' will be included...; post #33); and
-- preliminary tests results detected H5 genetic material in samples; (...Following the initial examination of Cho, a small amount of H5 virus was detected...; post #32);
-- a bacterial super-infection.

No data about mode of exposure, adherence to PPE wearing, and no details on treatments and current health status. Also, the soldier chemoprophylaxis status not mentioned at this point. No data about seasonal human vaccination.

I think the H5 genetic material description is just like the H5 description for the poultry. There have been no reports of H5 other than HPAI H5 or H5N! and the soldier was culling, so there is little doubt that this is an H5N1 infection (although it may be a mild infection similar to infections in Egypt last year).

I suspect the mild H5N1 infections are MUCH more widespread than reported (including India and Bangladesh).

[Anne]

Re: Korea-Suspected Human AI case

Hi ironorehopper

Hospitals and medical staff have also been taking treatment Tamiflu, in case of any incident. ( post one from treyfish )

So I think the soldier is taking tamiflu, and I read in a post from dutchy that he is taking antibiotics
( The release said the soldier??s condition improved after he received antibiotics and that everyone who had contact with him were also given medicine and will be monitored for 10 days )

it could be an avian flu ( because 2 tests > 0 ) AND a bacterial pneumonia.

[Giuseppe]

Re: Korea-Suspected Human AI case

A discussion thread on poultry culler infections in South Korea.

http://www.flutrackers.com/forum/showpost.php?p=58534&postcount=1

Subforums on past H5N1 outbreaks in South Korea.
http://www.flutrackers.com/forum/forumdisplay.php?f=370

You may agree that '60 per cent CFR' is a MEAN value, and it has a relative value. Variables to keep into account: - cases from geographical distinct areas; - infections due to different H5N1 lineages with distinct antigenic and genetic features; - cases detected for several years. Data is not part of an uniform set and should be careful evaluated.
It is also to be noted that recently Pakistani patients were confirmed positive by serology in presence of atypical H5N1 clinical presentation.

[Gert van der Hoek]

Re: Korea-Suspected Human AI case

4-22-08

Disease Management Division 22 suspected symptoms of avian influenza (AI) in the first round of a survey conducted by soldiers, AI type H5 virus has been detected.

However, the AI virus, the disease control division of the soldiers exposed to the virus but without byeongeneun taken out of the walls, and estimated that the possibility (bulhyeonseong infection).

Center for Disease Control Advisory Committee Advisory Committee Chairman bakseungcheol (Samsung Medical Center professor), "AI virus was detected in primary screening results," "AI, but the patient is infected with a bacterial infection in addition to the possibility there would be progress in mind," he said. In this case, the virus is still in the body, came to us out of the walls.

Disease management is the primary screening test headquarters separated from the patient gageommul antigen gene amplification (PCR) tests have been positive results, he said. Gabriel gobyeongwonseongin type H5 virus was found.

Advisory Committee Chairman night, "AI infection, such as fever and cough symptoms are excessive bacterial infection symptoms," "shallow, or bacterial pyeryeomil, AI virus, a bacterial infection, but in a separate proceeding would likely be separate report," he said. Patients will be put in operation before salcheobun showed symptoms of the flu jeomeseoda.

Chairman of the advisory night, "This is not a result of cell culture hwakjin through the PCR results confirm once again," "The World Health Organization (WHO) is currently a patient's AI bunryusang classified as suspected patients, but ultimately it is not confirmed." .

WHO has finalized the patient in three stages according to AI. AI was first exposed to the virus, symptoms of fever and pneumonia patients classified as suspicious, and if you see AI, since genetic tests (PCR) amplification, and the best AI AI virus positive patients classified as presumed. AI virus is a virus or antibodies final separation from the antibody tests, the increase is more than four times the hwakjinhwanja AI. Disease management is finalized headquarters was expected to take up to 1-3 weeks....

Meanwhile, disease management division, which was put to the task salcheobun 250 people, a medical condition such as a special observation, said medical staff.........

http://news.moneytoday.co.kr/view/mtview.php?no=2008042212164280935&type=2&NVEC

credits Pugmom

[Giuseppe]

Re: Korea-Suspected Human AI case

I think the H5 genetic material description is just like the H5 description for the poultry. There have been no reports of H5 other than HPAI H5 or H5N! and the soldier was culling, so there is little doubt that this is an H5N1 infection (although it may be a mild infection similar to infections in Egypt last year).

I suspect the mild H5N1 infections are MUCH more widespread than reported (including India and Bangladesh).

In fact. I've done a list for the soldier almost certain final H5N1 diagnosis. He meets WHO clinical features, laboratory results (although officially stated as preliminary).

[HenryN]

Re: Korea-Suspected Human AI case

Commentary

http://www.recombinomics.com/News/04220804/H5N1_Korea_Mild.html

[Giuseppe]

Re: Korea-Suspected Human AI case

Hi ironorehopper

Hospitals and medical staff have also been taking treatment Tamiflu, in case of any incident. ( post one from treyfish )

So I think the soldier is taking tamiflu, and I read in a post from dutchy that he is taking antibiotics
( The release said the soldier??s condition improved after he received antibiotics and that everyone who had contact with him were also given medicine and will be monitored for 10 days )

it could be an avian flu ( because 2 tests > 0 ) AND a bacterial pneumonia.

Well. He meets clinical and laboratory results for a confirmed human case of H5N1. In addition, chemoprophylaxis and prompt hospital admission may result in a more favorable outcome.

[Treyfish]

Re: Korea-Suspected Human AI case

<TABLE cellSpacing=0 cellPadding=0 width=555 border=0><TBODY><TR><TD><TABLE cellSpacing=0 cellPadding=0 width=555 border=0><TBODY><TR><TD class=link_title1 style="LINE-HEIGHT: 24px" span>Soldier Test Positive for Highly Pathogenic AI</TD></TR><TR><TD vAlign=top></TD></TR></TBODY></TABLE></TD></TR><TR><TD height=5></TD></TR><TR><TD><TABLE cellSpacing=0 cellPadding=0 width=189 border=0><TBODY><TR><TD width=216 bgColor=#6d7ebb height=6></TD></TR><TR><TD bgColor=#f4f4f4><!--Related News ???̺? ????--><!--Related News ???̺? ??--></TD></TR></TBODY></TABLE></TD></TR></TBODY></TABLE></TD></TR></TBODY></TABLE><!--?????? ???? ??-->A Korean soldier has tested positive for a highly pathogenic strain of avian influenza.

The 22-year-old man, identified only by his surname Cho, is suspected of having contracted the virus at a farm in Sunchang, North Jeolla Province. He had taken part in culling operations there to dispose of poultry likely to have been infected with the bird flu.

The Korea Centers for Disease Control and Prevention (KCDCP) said the H-Five-type virus, which causes the bird flu, was found in the soldier's blood sample.

The KCDCP said the H-Five-type virus is not usually found in humans, raising the possibility that the soldier may have been infected.

Authorities said a second test is under way, but it will take one to three weeks for the results.

They said Cho had a mild cold before participating in the culling operations. They did not rule out the possibility of viral pneumonia. http://english.kbs.co.kr/news/newsvi...key=2008042213</TD></TR></TBODY></TABLE>

[Anne]

Re: Korea-Suspected Human AI case

I don't find the non translate worlds with this translator :http://www.zkorean.com/dictionary.ph...=hwakjinhwanja


hwakjin and hwakjinhwanja : could be " virus " or viral , because :

This is not a result of cell culture hwakjin through the PCR results confirm once again
the increase is more than four times the hwakjinhwanja AI.

[HenryN]

Re: Korea-Suspected Human AI case

I don't find the non translate worlds with this translator :http://www.zkorean.com/dictionary.ph...=hwakjinhwanja


hwakjin and hwakjinhwanja : could be " virus " or viral , because :

This is not a result of cell culture hwakjin through the PCR results confirm once again
the increase is more than four times the hwakjinhwanja AI.

4X refers to antibody titer (definition of WHO confirmed case).