China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

[HenryN]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Commentary

http://www.recombinomics.com/News/01060903/H5N1_Beijing_7_Concerns.html

[HenryN]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Woman thought to have bird flu dies



Published: Jan. 6, 2009 at 2:27 PM


Order reprints | Feedback
<STYLE itxtvisited="1"> .content_embed { float: right; padding: 8px; width: 280px; margin: 0 0 8px 8px; border: 1px solid #ccc; background: #fff; } .photo_embed { float: right; width: 301px; margin: 0 0 8px 8px; background: #fff; } .video_embed { float: right; width: 301px; margin: 0 0 8px 8px; background: #fff; }</STYLE>BEIJING, Jan. 6 (UPI) -- A woman suspected of having contracted bird flu has died, local health officials in Beijing said Tuesday.
Zhao Qingchao, an official with Langfang municipal government, said Huang Yanqing apparently was the only one of 13 people who ate the duck to become fatally ill, the state-run news agency Xinhua reported Tuesday.
Huang bought nine ducks at the Yanjiaoqingong Market in Langfang City of Beijing's neighboring Hebei Province Dec. 19, then cleaned the ducks' internal organs before giving three ducks to other people, the Beijing Municipal Health Bureau said.
"According to the initial investigation, a total of 13 people have eaten the duck and Huang is the only one who fell ill," Zhao said. "We had thoroughly combed all stands in the market."
He said the ducks' origin was traced to Jixian County in Tianjin Municipality.
No bird flu case had been found in Langfang City so far, a spokesperson with China's Ministry of Agriculture told Xinhua.
The Beijing Municipal Health Bureau said 116 people were in close contact with the victim. One healthcare professional in contact with Huang contracted bird flu, but recovered, the bureau said.
Beijing officials reported the incident to the World Health Organization, as well as health authorities in Hong Kong and Macao. Official also have begun bird flu prevention and control measures.

http://www.upi.com/Science_News/2009/01/06/Woman_thought_to_have_bird_flu_dies/UPI-93701231270068/

[AlaskaDenise]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

[quote=niman;200400]Commentary

http://www.recombinomics.com/News/01..._Concerns.html
Clade 7 H5N1 In Beijing Raises Pandemic Concerns

Recombinomics Commentary 20:06
January 6, 2009

Gene sequencing by the National Avian Influenza Reference Laboratory indicated that this virus is very similar to the avian influenza virus variant isolated in Shanxi in 2006.

A 19-YEAR-OLD Beijing woman who suffered the city's first human case of bird flu since 2003 has died, municipal health authorities said yesterday.

The sequencing comments above are from the OIE report on the H5N1 from the Jiangsu outbreaks last month, followed by the most recent confirmed human case in China (see updated map), who died yesterday. The “virus variant” is clade 7, as seen in phylogenetic analysis of A/chicken Shangxi/02/2006 in the latest WHO on vaccine targets. On the same branch is A/Beijing/01/2003, which was isolated from the first H5N1 confirmed case in mainland China.

It is likely that the latest case was also infected by clade 7 H5N1, which is vaccine resistant because most vaccines target clade 1 or 2, which are significantly different than clade 7.

The details of the Jiangsu outbreaks are unclear. Some local media reports suggested the outbreak was large and involved dead poultry that was shipped to market. Other reports acknowledged the H5N1 infection, but noted that the infected birds were asymptomatic and identified through routine screening.

However, if the latest case was fatally infected by clade 7 from an asymptomatic duck, then the potential for additional cases is high because the virus can travel and dispress undetected. Moreover, since clade 7 is resistant to the most common vaccines, it could be widespread.

Clade 7 was also reported in Vietnam in August, and a clade 7 target was recently identified by the WHO. There currently is no clade 7 pandemic vaccine, and the selected target is only proposed as a target, as indicated in the most recent WHO vaccine update. The earlier presence of clade 7 in Vietnam may be related to the recent confirmed human case in northern Vietnam, which was announced today.

Thus, more detail about the H5N1 in Beijing and Vietnam, including sequence data from these isolates, as well as the WHO vaccine target, A/chicken/Vietnam/NCVD-016/2008, would be useful.

The presence of vaccine resistant H5N1 in asymptomatic ducks in Beijing would create significant pandemic concerns.

[AlaskaDenise]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Can we assume that Hunang became infected as the result of a higher viral load from the process of cleaning the bird?

.

[HenryN]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Can we assume that Hunang became infected as the result of a higher viral load from the process of cleaning the bird?

.

Cooking kills the virus, so those most at risk are those who handle the bird prior to cooking.

[HenryN]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

<LI class="dateStamp first"><SMALL>JANUARY 7, 2009</SMALL> <!-- ID: SB123127188802458267 --><!-- TYPE: Health --><!-- DISPLAY-NAME: Health --><!-- PUBLICATION: The Wall Street Journal Interactive Edition --><!-- DATE: 2009-01-07 00:01 --><!-- COPYRIGHT: Dow Jones & Company, Inc. --><!-- ORIGINAL-ID: --><!-- article start --><!--CODE=SUBJECT SYMBOL=OWONCODE=SUBJECT SYMBOL=OASNCODE=STATISTIC SYMBOL=FREECODE=INDUSTRY SYMBOL=DHC-->Beijing Woman Dies of Avian Flu

Authorities on Alert After Beijing Death; More Bird Cases Seen

• Article
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more in Health ?

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By GORDON FAIRCLOUGH

SHANGHAI -- A 19-year-old Beijing woman has died of bird flu, the first human case of the virus in China since February last year, the government said Tuesday, putting public-health officials on higher alert for a possible resurgence of the disease this winter.
The woman, who lived on the outskirts of China's capital, succumbed Monday morning to the H5N1 strain of avian influenza, according to a statement by the Beijing health bureau. It didn't say how she became infected.
Mao Qun'an, the spokesman for the Ministry of Health, said public-health officials have forecast a likely increase in avian influenza among birds this year, raising the possibility of more human infections.
"We have been paying great attention" to the possibility of human illnesses, Mr. Mao said. But, he added, because bird flu isn't readily transmissible to people, there is "no need to get nervous."
Bird flu remains primarily a threat to poultry, not humans, but the World Health Organization and national public-health authorities remain on guard because the virus has the potential to mutate into a more contagious form and spark a pandemic.
Also on Tuesday, health officials in Vietnam said an 8-year-old girl had tested positive for the disease, the Associated Press reported. It was the first human case reported in that country in nearly a year.
Human infections with H5N1 peaked in 2006, when 115 cases -- 79 of them fatal -- were reported to the WHO. In 2008, there were 40 cases of human infection with H5N1, leading to 30 deaths -- a tiny number compared with the death toll from ordinary flu.
Since fall, outbreaks of avian influenza in birds have been reported in countries including Vietnam, Thailand, India, Togo and Germany. One person died of bird flu in Indonesia in November, and a teenager in Egypt died of the disease in December.


India Battles an Outbreak of Bird Flu

<SMALL>1:17</SMALL> Poultry farmers in India's eastern West Bengal state face ruin after fresh outbreak of bird flu. Worries that the flu virus could mutate and could cause a global pandemic. Courtesy Reuters.





Chinese health officials said they have stepped up monitoring and infection-control measures since the Beijing woman's diagnosis. People who had close contact with the woman have been placed under medical observation, but none have shown any sign of infection, officials said. An official in the village where the woman lived said disinfection teams had visited the area Monday.
The Ministry of Agriculture and local agriculture officials said they have received no reports of avian-flu outbreaks in poultry in or around Beijing. Last month, the authorities ordered the slaughter of more than 350,000 chickens after routine testing of eggs turned up signs of bird flu in an east-coast province, more than 1,000 kilometers from Beijing.
Nyka Alexander, a spokeswoman for the WHO in Beijing, said the Chinese government had informed the organization of Monday's death.
Authorities in Hong Kong -- where tens of thousands of chickens were culled in December after dead birds tested positive for H5N1 -- as well as in Macau and Taiwan also were alerted, China said.
<CITE class=tagline>?Kersten Zhang in Beijing contributed to this article.</CITE> Write to Gordon Fairclough at gordon.fairclough@wsj.com
<!-- article end -->

http://online.wsj.com/article/SB123127188802458267.html?mod=#printMode

[AlaskaDenise]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Cooking kills the virus, so those most at risk are those who handle the bird prior to cooking.

I had assumed she "gave the birds" as uncooked birds, but it could be either way, since she did the prep work either way.

IF the reports about the HCW infection are true, does that indicate poor biosecurity or better mammalian-adapted genetics?

.

[HenryN]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

I had assumed she "gave the birds" as uncooked birds, but it could be either way, since she did the prep work either way.

IF the reports about the HCW infection are true, does that indicate poor biosecurity or better mammalian-adapted genetics?

.

One report said the victim cleaned all 9 birds.

H5N1 in a HCW is a major red flag. UPI said the HCW had bird flu. Several reports said the nurse had a fever. No report said she had a fever due to something other than bird flu.

Clade 7 has a LOT of RBD changes and some are in patients from Indonesia.

[sharon sanders]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

We do not know with certainty that this is a Clade 7.

[HenryN]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

We do not know with certainty that this is a Clade 7.

I don't think anyone knows with certainty for the latest human case, but the Jiangsu outbreak is clear, while Shangxi in 2006 and Beijing in 2003 are public.

For the latest case, the timing and location strongly point toward clade 7. I would be VERY surpised if this isn't a clade 7 case.

[Commonground]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Beijing a 19-year-old woman on the 5th bird flu death

-snip-
Place of residence were found in patients with bird flu poultry

New Express inquiry, according to "Beijing Morning Post" reported that, following the January 5 from the city of Chaoyang District Health Board found a case of human infection with bird flu, the Beijing veterinary departments around the residence of the patients closely investigation results showed that patients living not found in the vicinity of poultry outbreaks of avian flu.

After Beijing, the veterinary department investigation, the patient place of residence and its surrounding areas within 10 kilometers without poultry. As of Chaoyang, Tongzhou, Miyun District, such as epidemiological investigation and found no abnormal poultry. November 2008 National Immunization checks revealed that the Beijing bird flu immunization density 100 percent, 100 percent passing rate of antibody. Detection of the city in 2008 a total of 41,641 samples pathogenic avian influenza were the results were negative.

Beijing veterinary departments to further step up bird flu prevention and control efforts to ensure safety of poultry products, first of all, continue to strengthen bird flu immunization, monitoring and other measures, case-by-village, door-to-door, by field verification of immunization density, the new and补栏timely immunization due poultry-free premium to ensure that the density and quality of immunization. From yesterday, the focus on carrying out a special inspection of law enforcement activities, according to market live poultry trading investigation at the scene, such as acts of slaughter and私屠滥宰. At the same time strengthen supervision and inspection of highway animal epidemic prevention stations on duty checking the work of the animals and their products and quarantine supervision.
-snip-

[Treyfish]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Beijing confirmed bird flu death in patients with urge you alert <TABLE border=0 cellSpacing=0 cellPadding=0 width="96%" align=center><TBODY><TR><TD height=20 align=middle>

??官方：北京确诊一禽流感病例患者亡

- Official: Beijing confirmed a bird flu patients die </TD></TR></TBODY></TABLE><TABLE style="MARGIN-TOP: 3px; FONT-SIZE: 16px" border=0 cellSpacing=0 cellPadding=0 width="96%" align=center>

打印版 【 阿波罗新闻网 2009-01-07讯】

Print version 【Apollo News Network 2009-01-07讯】
<!--内容简介-->
<TBODY><TR><TD vAlign=top><TABLE class=font14 border=0 cellSpacing=0 cellPadding=0 width="96%" align=center><TBODY><TR><TD style="WIDTH: 740px; COLOR: #363696; LEFT: 0px" class=dot_pane>

内容摘要阿波罗网编者按：提醒大陆网友注意，情况绝对比官方报道严重。

A summary of the Apollo Network Editor's note: to remind the users attention to the mainland, the situation is absolutely serious than the official reported.

呼吁大家警惕。

Appeal to everyone vigilance. </TD></TR></TBODY></TABLE></TD></TR><TR><TD><TABLE class=article_font border=0 cellSpacing=0 cellPadding=5 width="100%"><TBODY><TR><TD style="WIDTH: 750px; LEFT: 0px" id=fontzoom><!--正文--><TABLE border=0 cellSpacing=4 cellPadding=1 align=center><TBODY><TR><TD vAlign=top align=middle></TD></TR><TR><TD vAlign=top align=middle></TD></TR></TBODY></TABLE>

1月6日，黄某的亲人在介绍黄某曾居住的地方。

January 6, Hwang loved ones, introducing Huang had a place to live.

当日，北京市卫生局发布通报称，北京市确诊一例人感染高致病性禽流感病例，经全力抢救无效死亡 。

On that day, the Beijing Municipal Health Bureau released briefing that Beijing confirmed case of human infection of highly pathogenic avian influenza cases, by the full died.

患者黄某，女，19岁，现住北京市朝阳区三间房，2008年12月24日发病，12月27日症状加重后入院 治疗，经全力救治无效，于2009年1月5日7时20分死亡。

Huang patients, female, 19 years old, and currently residing in Chaoyang District, Beijing 3 rooms, December 24, 2008 incidence, December 27 admitted to hospitals for treatment after the symptoms aggravated by the full treatment ineffective, in January 5, 2009 7 When the death of 20 points.

疫情发生后，北京市政府高度重视，迅速按照《人感染高致病性禽流感应急预案》的要求采取了相应的防控措施， 并加强相关流行病学调查工作。

Epidemic occurred, the Beijing Municipal Government attaches great importance to the rapid in accordance with the "human infection of highly pathogenic avian influenza contingency plans" to take the appropriate prevention and control measures, and strengthen the epidemiological investigation.

同时，对全部密切接触者实行严格的医学观察。

At the same time, all close contacts strict medical observation.

截至目前未发现异常临床表现。

As of now no abnormal clinical manifestations.

新华社记者公磊摄

Xinhua News Agency reporter Gong Leishe

<CENTER><TABLE border=0 cellSpacing=4 cellPadding=1 align=center><TBODY><TR><TD vAlign=top align=middle> </TD></TR><TR><TD vAlign=top align=middle></TD></TR></TBODY></TABLE></CENTER>

1月6日，黄某的亲友十分悲痛。

January 6, Hwang's relatives and friends are very sad.

当日，北京市卫生局发布通报称，北京市确诊一例人感染高致病性禽流感病例，经全力抢救无效死亡 。

On that day, the Beijing Municipal Health Bureau released briefing that Beijing confirmed case of human infection of highly pathogenic avian influenza cases, by the full died.

新华社记者公磊摄

Xinhua News Agency reporter Gong Leishe</TD></TR></TBODY></TABLE></TD></TR></TBODY></TABLE>
http://74.125.93.104/translate_c?hl=...nR9xmiVFTp1gjQ

[HenryN]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Commentary

http://www.recombinomics.com/News/01070901/H5N1_Beijing_H2H.html

[Treyfish]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

The possibility of bird flu occurred in animals large emergency notification live trading investigation

2009年01月07日08:06 [ 我来说两句

At 8:06 on January 7, 2009 [I来说两句

] [字号： 大 中 小 ]

] [Font Size: Xinhuanet]

来源：京华时报

Source: Beijing Times

<SOHUADCODE></SOHUADCODE>

农业局：下发紧急通知严查活禽交易

Agriculture: issued an urgent circular trading investigation of live birds

本报讯（记者叶洲文静）市兽医部门已经对患者居住地周围进行了严密排查。

By (Xinhua叶洲quiet) City veterinary departments have been on the patients had a place of residence around the investigation closely.

患者居住地及周边地区10公里内无家禽饲养。

Patients place of residence and its surrounding areas within 10 kilometers without poultry.

经对朝阳、通州、密云等区县流行病学调查，未发现家禽异常情况。

As of Chaoyang, Tongzhou, Miyun counties, such as epidemiological investigation and found no abnormal poultry.Last night, the city of Agriculture poultry market focus for a special inspection of the emergency notice has been issued, the market live poultry trading investigation.

将由市动物卫生监督所等相关部门启动对屠宰场、养殖场等区域活禽类的突击检查。

Urban Animal Health will monitor the start of the relevant departments, such as slaughterhouses, farms and other types of regional spot checks of live birds.

北京市也出台措施，继续强化禽流感免疫，即日起，集中开展一次专项执法检查。

Beijing has also introduced measures to continue to strengthen the avian flu immunization, with immediate effect, focus on a special inspection of law enforcement.

卫生部：今年动物禽流感发生可能性大

The Ministry of Health: This year the possibility of animal bird flu occurred in large

本报讯（记者叶洲）昨天，卫生部表示，卫生部和农业部有关专家最近曾就今年的动物禽流感及人禽流感疫情进行 了风险评估。

By (Xinhua叶洲) yesterday, the Ministry of Health said that the Ministry of Health and the Ministry of Agriculture experts have recently been on this year's animal avian influenza and human bird flu risk assessment carried out.

专家预测，今年发生动物禽流感的可能性大。

Experts predict that this year the possibility of avian influenza of animal large.

新闻发言人毛群安称，卫生部已经对全国预防人感染高致病性禽流感的工作包括病人的诊断、治疗标准，以及对疫 情的监测、报告进行了全面的部署，并根据过去工作的实际情况，对有些管理的要求进行了调整，今年提出要在过 去的基础上加大对人感染高致病性禽流感疫情的监测力度。

Press spokesman Mao Qun'an said the Ministry of Health has been the country to prevent human infection of highly pathogenic avian influenza, including the patient's diagnosis, treatment standards, as well as monitoring of the epidemic, the report conducted a comprehensive deployment, and in accordance with the actual situation of the past work , for some management requirements have been adjusted in the past year proposed to increase the basis of human infection of highly pathogenic avian influenza epidemic monitoring.http://74.125.93.104/translate_c?hl=...JokqvSlTSUf8FA

[Treyfish]

Re: China: Woman, 19, Confirmed H5N1 Death - Contacts Monitored

Beijing 1 celebrity hospital patients died of bird flu had been suspected bird flu in accordance with reception

2009年01月07日08:04 [ 我来说两句

At 8:04 on January 7, 2009 [I来说两句

] [字号： 大 中 小 ]

] [Font Size: Xinhuanet]

来源：京华时报

Source: Beijing Times

<SOHUADCODE></SOHUADCODE>

本报讯（记者叶洲）昨晚，卫生部、北京市卫生局通报，北京市确诊一例人感染高致病性禽流感病例，该患者已于 1月5日上午死亡。

By (Xinhua叶洲) last night, the Ministry of Health, the Beijing Municipal Health Bureau briefing in Beijing confirmed case of human infection of highly pathogenic avian influenza cases, the patient was the morning of January 5 deaths.

目前，北京市有关部门已对全部密切接触者实行了严格的医学观察，尚未发现异常临床表现。

At present, relevant departments in Beijing have been in close contact with all the strict medical observation, have not yet shown any abnormal symptoms. This is the first of this year found that people infected with highly pathogenic bird flu, but also Beijing's first case.

据介绍，患者黄某，女，19岁，现住北京市朝阳区三间房。

According to the briefing, Huang patients, female, 19 years old, and currently residing in Chaoyang District, Beijing 3 room.

2008年12月24日发病，12月27日症状加重后入院治疗，经全力救治无效，患者于2009年1月5日 上午7时20分死亡。

December 24, 2008 incidence, December 27 after aggravating symptoms hospitalized invalid by the full treatment, the patient was at 7:20 on January 5, 2009 death.

1月5日，北京市疾病预防控制中心和军事医学科学院对患者标本进行平行检测，中国疾病预防控制中心对患者标 本进行复核检测，结果显示禽流感病毒（H5N1）核酸阳性。

January 5, the Beijing Municipal Center for Disease Control and Prevention and the Academy of Military Medical Sciences of patient specimens parallel testing, the Chinese Center for Disease Control and Prevention review of patient specimens for testing, results showed that the avian flu virus (H5N1) nucleic acid positive.

根据世界卫生组织人感染高致病性禽流感确诊病例定义和我国诊断标准，卫生部人禽流感防控专家组判定该病例为 人感染高致病性禽流感确诊病例。

According to World Health Organization of human infection of highly pathogenic avian influenza confirmed case definition and China's diagnostic standards for human avian influenza prevention and control of the Ministry of Health expert group to determine the cases of human infection of highly pathogenic avian influenza confirmed cases.

目前，卫生部门已对全部密切接触者实行医学观察，尚未发现异常临床表现。

At present, the health sector has been in close contact with all persons under medical observation, have not yet shown any abnormal symptoms.

此外，该患者的有关情况，卫生部已向世界卫生组织、港澳台地区和部分国家通报。

In addition, the patients with the situation, the Ministry of Health has the World Health Organization, Hong Kong, Macao and Taiwan regions and part of national communications.

医院：曾按疑似禽流感病例接诊

Hospital: has suspected bird flu in accordance with reception

本报讯（记者李秋萌）昨晚，记者从北京胸部肿瘤结核病医院获悉，黄某于去年12月底入住该院，经查发现其有 符合患禽流感的相关症状，但因尚未得到相关部门检测证实，初步判断其为“疑似禽流感”病例，并上报至疾控卫 生部门，因其症状加剧，随即被转入ICU病房进行治疗。

By (Reporter Li Meng) last night, reporters from Beijing chest tumor tuberculosis hospital was informed that Mr. Hwang admitted to the hospital by the end of December last year, he has identified as suffering from bird flu in line with related symptoms, but has not yet been confirmed detection of the relevant departments The preliminary judge for the "suspected bird flu" cases, and reported to the CDC health sector, because of their symptoms exacerbated, the woman was transferred to ICU wards for treatment.

医院相关人员表示，黄某无职业，对于“是否为北京人”的问题，院方未做出否定答复。

Hospital officials said that Huang had no paid employment, as to "whether the Peking Man", the hospital did not make a negative response.http://74.125.93.104/translate_c?hl=...jFLevqTYOCbseQ