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Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infection
Ryan Zarychanski MD, Tammy L. Stuart PhD, Anand Kumar MD, Steve Doucette MSc, Lawrence Elliott MD MSc, Joel Kettner MD MSc, Frank Plummer MD
Conclusions
The severity of illness among patients infected with pandemic
H1N1 influenza was associated with the length of time from
onset of symptoms to treatment with antiviral therapy and
with the presence of underlying medical comorbidities, relative
to controls not admitted to hospital. First Nations ethni -
city was associated with severe disease, relative to other ethnic
groups. These data may have implications for proactive
public health and primary care using outreach methods at the
community level, whether for public health education, prioritization
of vaccination efforts or strategies for antiviral treatment.
Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infection
Ryan Zarychanski MD, Tammy L. Stuart PhD, Anand Kumar MD, Steve Doucette MSc, Lawrence Elliott MD MSc, Joel Kettner MD MSc, Frank Plummer MD
Conclusions
The severity of illness among patients infected with pandemic
H1N1 influenza was associated with the length of time from
onset of symptoms to treatment with antiviral therapy and
with the presence of underlying medical comorbidities, relative
to controls not admitted to hospital. First Nations ethni -
city was associated with severe disease, relative to other ethnic
groups. These data may have implications for proactive
public health and primary care using outreach methods at the
community level, whether for public health education, prioritization
of vaccination efforts or strategies for antiviral treatment.
