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  • Lassa fever prophylaxis proposed

    Source: http://www.eht-forum.org/news.html?f...from=home&id=0

    Thursday 25 November 2010
    Lassa fever prophylaxis proposed
    Review offers evidence-based advice for use of antiviral drugs after exposure to the bioterrorism agent

    Antiviral drugs against the Lassa fever virus should be prescribed as a preventative measure when people have certain high-risk exposures, such as getting pierced by a contaminated needle, according to research published this month in Clinical Infectious Diseases.

    Specific guidelines for use of the drug ribavirin are proposed by Daniel Bausch and colleagues after a systematic review of evidence on the disease, the drug and the illness.

    ?These guidelines may also serve for PEP [post-exposure prophylaxis] for the other arenaviruses causing hemorrhagic fever (Junin, Machupo, Guanarito, Sabi?, and Flexal viruses) as well as for Crimean-Congo hemorrhagic fever,? write the authors...
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