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In vitro virucidal effect of mouthrinse containing C31G on seasonal influenza viruses

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  • In vitro virucidal effect of mouthrinse containing C31G on seasonal influenza viruses

    J Microbiol Biotechnol. 2014 Apr 1. [Epub ahead of print]
    In vitro virucidal effect of mouthrinse containing C31G on seasonal influenza viruses.
    Lee DH1, Youn HN, Park JK, Kang BH, Kang JH, Lee JB, Park SY, Choi IS, Lee SW, Song CS.
    Author information
    Abstract

    C31G is a potent antimicrobial agent and can disrupt the microbial membrane by the alkyl portion of the molecule. The objective of this study was to evaluate the virucidal effectiveness of C31G and mouthrinse containing C31G (Sense-Time?) on seasonal influenza viruses. Evaluation of the virucidal activity against influenza viruses was performed with end-point titration in 10-days old chicken embryo and Madin-Darby canine kidney cell. In vitro studies demonstrated that C31G and Sense-Time? inhibited the growth of seasonal influenza viruses even in the presence of 5% organic material. Gargling with C31G or Sense-Time? would enhance oropharyngeal hygiene which would be helpful for reducing influenza transmission.

    PMID:
    24690639
    [PubMed - as supplied by publisher]

    Free full text

    C31G is a potent antimicrobial agent and can disrupt the microbial membrane by the alkyl portion of the molecule. The objective of this study was to evaluate the virucidal effectiveness of C31G and mouthrinse containing C31G (Sense-Time) on seasonal influenza viruses. Evaluation of the virucidal act …
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