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April 27th, 2009, 04:00 PM
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Sequences at Genbank!
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April 27th, 2009, 04:04 PM
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Re: sequences at genbank !
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April 27th, 2009, 04:06 PM
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Re: sequences at genbank !
Is there anything we should be worried about in those sequences gsgs.....?
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April 27th, 2009, 04:27 PM
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Re: sequences at genbank !
differences to other selected genomes in promille for each of the 8 segments:
(some segments may be missing, where "0" is listed)
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April 27th, 2009, 04:31 PM
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Re: sequences at genbank !
Code:
13: 30, 36, 45, 49, 31,499,113, 41 A/Turkey/MO/24093/99(H1N2)
153:158,136,132,255,156, 82, 43,179 A/swine/Virginia/670/1987(H1N1)
154:158,128,125,246,158, 80, 50,171 A/swine/Germany/2/1981(H1N1)=1578
155:161,145,144,259,159, 80, 60,185 A/swine/Spain/53207/2004(H1N1)
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April 27th, 2009, 04:57 PM
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Re: sequences at genbank !
So it's clearly a human-swine-avian recombinant. Just like they said. And large sections of the genome have been copied faithfully for years and years. The swine part, in particular, is especially stable.
And it has happened pretty recently, as such things go.
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April 27th, 2009, 06:05 PM
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Re: sequences at genbank !
here the best matches in the 8 segments
this is from my last update, early 2009 (maybe only 2007 in PB1, as I just see)
columns are:
difference in promille
different nucleotides
length of matching part
enumeration
strain
0 0 2280 6904 California/04/2009-04-01/(H1N1)
Code:
--------------------------------------------------------------
304 24 787 2897 Turkey/MO/24093/99(H1N2)
306 69 2249 3703 mallard Dk/South Dakota/Sg-00127/07(H3N2)
306 69 2249 3704 mallard Dk/South Dakota/Sg-00128/07
307 69 2246 3702 pintail Dk/South Dakota/Sg-00126/07(H3N2)
307 69 2247 3701 mallard Dk/South Dakota/Sg-00125/07(H3N2)
321 50 1557 2887 Sw/Texas/4199-2/98(H3N2)
333 52 1557 2888 Sw/Minnesota/9088-2/98(H3N2)
333 52 1557 2895 Sw/Iowa/8548-1/98
342 78 2280 3760 Sw/Korea/JNS06/04(H3N2)
343 54 1573 2894 Wisconsin/10/98(H1N1)
346 79 2280 3705 Sw/Minnesota/55551/00(H1N2)
-------------------------------------------------------------
312 71 2271 5644 Wisconsin/10/98(H1N1)
340 77 2259 5652 mallard Dk/South Dakota/Sg-00125/07(H3N2)
351 80 2274 5656 Sw/Indiana/9K035/99(H1N2)
365 83 2271 5638 Sw/Nebraska/209/98(H3N2)
365 83 2271 5639 Sw/Iowa/533/99(H3N2)
365 83 2271 5640 Sw/Iowa/569/99(H3N2)
365 83 2271 5641 Sw/Minnesota/593/99(H3N2)
369 84 2271 5657 Sw/Korea/CAN04/05(H3N2)
369 84 2274 5675 Dk/NC/91347/01(H1N2)
374 43 1149 4066 Sw/Minnesota/9088-2/98(H3N2)
374 43 1149 4068 Sw/Iowa/8548-1/98
374 85 2271 5668 Sw/Illinois/100085A/01(H1N2)
374 85 2271 5670 Sw/Ohio/891/01(H1N2)
378 86 2271 5654 Sw/Iowa/930/01(H1N2)
378 86 2271 5682 Sw/Korea/CY04/07(H3N2)
378 86 2271 5683 Sw/Korea/CY05/07(H3N2)
382 44 1149 4067 Sw/Texas/4199-2/98(H3N2)
383 87 2271 5658 Sw/Korea/CAS07/05(H3N2)
383 87 2271 5659 Sw/Korea/CAS09/06(H3N2)
383 87 2271 5690 Sw/Indiana/P12439/00(H1N2)
------------------------------------------------------------------
370 79 2130 4925 mallard duck/South Dakota/Sg-00128/2007
370 79 2131 4923 pintail duck/South Dakota/Sg-00126/2007(H3N2)
373 79 2117 4922 mallard duck/South Dakota/Sg-00125/2007(H3N2)
381 79 2073 4924 mallard duck/South Dakota/Sg-00127/2007(H3N2)
390 84 2151 2977 Swine/Nebraska/209/98 (H3N2)
390 84 2151 2978 Swine/Iowa/533/99 (H3N2)
390 84 2151 2979 Swine/Iowa/569/99 (H3N2)
390 84 2151 2980 Swine/Minnesota/593/99 (H3N2)
390 84 2151 3015 Swine/Illinois/100084/01 (H1N2)
399 86 2151 3011 Swine/Minnesota/55551/00 (H1N2)
----------------------------------------------------------------
470 80 1700 344 Swine/Indiana/P12439/00 (H1N2)
482 82 1700 280 Swine/Indiana/9K035/99 (H1N2)
500 85 1700 504 Turkey/MO/24093/99(H1N2)
505 86 1700 2468 swine/Minnesota/1192/2001(H1N2)
511 87 1700 339 Swine/Ohio/891/01(H1N2)
517 88 1700 549 SW/MN/23124-T/01(H1N2)
517 88 1700 2115 swine/Guangxi/17/2005(H1N2)
529 90 1700 550 SW/MN/23124-S/01(H1N2)
529 90 1700 552 SW/MN/16419/01(H1N2)
535 91 1700 345 Swine/Illinois/100085A/01 (H1N2)
542 56 1032 296 Wisconsin/10/98 (H1N1)
------------------------------------------------------------------
250 13 520 6925 Sw/Oklahoma/18717/99(H3N2)
251 13 516 6921 Sw/Colorado/23619/99(H3N2)
262 14 533 6922 Sw/Wisconsin/14094/99(H3N2)
262 14 533 6924 Sw/Illinois/21587/99(H3N2)
263 14 531 6923 Sw/Oklahoma/18089/99(H3N2)
312 16 512 6926 Sw/NorthCarolina/16497/99(H3N2)
316 31 980 6927 Turkey/MO/24093/99(H1N2)
329 48 1457 6963 Sw/Iowa/533/99(H3N2)
336 49 1457 6961 Sw/Indiana/P12439/00(H1N2)
336 49 1457 6969 Sw/Korea/CY04/07(H3N2)
336 49 1457 6970 Sw/Korea/CY05/07(H3N2)
337 33 979 6928 Sw/Texas/4199-2/98(H3N2)
337 33 979 6929 Sw/Iowa/8548-1/98
339 19 560 6972 SW/NC/45319/99(H1N2)
339 19 560 6973 SW/NC/17366/01(H1N2)
339 19 560 6974 SW/CO/17871/01(H1N2)
343 50 1457 6971 Sw/Korea/CY09/07(H3N2)
------------------------------------------------------------------
589 83 1409 1741 Sw/England/195852/92(H1N1)
652 92 1409 1742 Sw/Germany/Vi5698/95(H1N1)
712 98 1376 1746 Sw/Belgium/74/85(H1N1)
751 101 1344 1773 Sw/Ille et Vilaine/1455/99(H1N1)
753 105 1394 1772 Sw/Cotes d'Armor/1488/99(H1N1)
754 106 1404 1749 Italy/1424-4/95(H1N1)
765 108 1410 1737 Sw/Belgium/1/83(H1N1)
777 104 1338 1777 Sw/Italy/1492/97(H1N1)
786 103 1310 1778 Sw/Italy/1513-8/98(H1N1)
787 111 1410 1739 turkey/France/87075/87(H1N1)
787 111 1410 1788 Sw/Italy/53949/04(H1N1)
787 111 1410 1789 Sw/Italy/65296/04(H1N1)
794 112 1410 1738 Sw/Finistere/3616/84(H1N1)
795 102 1282 1750 Sw/Italy/1424-3/95(H1N1)
801 113 1410 1736 Sw/Lot/2979/82(H1N1)
801 113 1410 1790 Sw/Spain/53207/04(H1N1)
801 113 1410 1791 Sw/Italy/247578/04(H1N1)
801 113 1410 1793 Sw/Spain/51915/03(H1N1)
812 106 1305 1774 Cotes d'Armor/1121/00(H1N1)
815 115 1410 1794 Sw/Virginia/671/1987(H1N1)
--------------------------------------------------------------------
230 22 955 2735 Sw/HK/5190/99(H3N2)
230 22 955 2736 Sw/HK/5200/99(H3N2)
230 22 955 2737 Sw/HK/5212/99(H3N2)
261 25 955 2739 Sw/HK/1197/02(H3N2)
261 25 955 2740 Sw/HK/1144/02(H3N2)
272 26 955 2738 Sw/HK/9745/01(H3N2)
272 26 955 2743 HK/1774/99(H3N2)
293 28 955 2741 Sw/HK/7982/00(H3N2)
314 30 955 2742 Sw/HK/9296/01(H3N2)
345 33 955 2721 Sw/Leipzig/145/92(H3N2)
366 35 955 2726 Sw/Cotes d'Armor/1482/99(H1N1)
397 38 955 2722 wild boar/Germany/WS169/06(H3N2)
397 38 955 2727 Sw/Italy/1521/98(H1N2)
------------------------------------------------------------
346 29 838 6427 Sw/Texas/4199-2/98(H3N2)
346 29 838 6428 Sw/Minnesota/9088-2/98(H3N2)
357 30 838 6429 Sw/Iowa/8548-1/98
381 32 838 6444 Sw/Indiana/9K035/99(H1N2)
395 33 835 6436 Sw/North Carolina/98225/01(H1N2)
395 33 835 6437 Sw/Minnesota/55551/00(H1N2)
395 33 835 6445 SW/MN/3327/00(H1N2)
395 33 835 6453 SW/IN/14810-T/01(H1N2)
395 33 835 6454 SW/IN/14810-S/01(H1N2)
395 33 835 6455 Sw/Korea/CAS09/06(H3N2)
407 34 835 6456 Sw/Korea/CAN04/05(H3N2)
407 34 835 6457 Sw/Korea/CAS07/05(H3N2)
407 34 835 6467 Sw/Korea/CAS08/05(H1N1)
407 34 835 6506 Sw/Iowa/930/01(H1N2)
417 35 838 6430 Sw/Nebraska/209/98(H3N2)
417 35 838 6438 Turkey/MO/24093/99(H1N2)
417 35 838 6483 turkey/OH/313053/04(H3N2)
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April 27th, 2009, 06:24 PM
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Editor, Senior Moderator
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Re: sequences at genbank !
from post #4:
(deleted data)
Interesting history, eh?
GS - what exactly are you comparing - the whole sequence?
.
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Last edited by AlaskaDenise; April 27th, 2009 at 06:41 PM.
Reason: delete misleading data
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April 27th, 2009, 06:29 PM
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Re: sequences at genbank !
Quote:
Originally Posted by vinny
Is there anything we should be worried about in those sequences gsgs.....?
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On the contrary, the fact that all of the California sequences have a Lysine at position 627 of the PB2 segment is fantastic news. Years of research would suggest that the California virus does not replicate well in the cooler temperatures of the upper respiratory system. Perhaps that is why we are seeing patients complain of nausea, vommiting and diarrhea. This thing replicates better in the digestive tract?
Suggests perhaps that the virus is more transmittable through touch and contaminated surfaces than coughs and sneezes. Might also suggest that the best way to detect the virus in a suspect patient is through anal swabs rather than nasal swabs. Virus loads in the intestines probably greater than the respiratory tract.
Now, what about the other sequences, particullary Mexico, where we have a large number of deaths. Is the E627K mutation present?
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April 27th, 2009, 06:33 PM
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Re: sequences at genbank !
well, this is similar to American swine e.g.
A/swine/OH/511445/2007(H1N1)
in segments 123458
67 are European swine , but also A/swine/Virginia/670/1987(H1N1)
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April 27th, 2009, 06:34 PM
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Re: sequences at genbank !
Mama - would that suggest that the Mexican strain has undergone more mutation?
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April 27th, 2009, 06:34 PM
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Re: sequences at genbank !
Quote:
Originally Posted by AlaskaDenise
from post #4:
Interesting history, eh?
GS - what exactly are you comparing - the whole sequence?
.
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The H5N1 are not good matches. gsgs's numbers indicate the number of differences between A/california segments and the segments in the list of sequences he compared A/Calif with. The sequences only match in a segment if there are 0 differences. Hence my comment. If you look down column by column and spot the 0s and ignore the rest, you end up with with a 100% match to A/calif, and individual 100% matches to a mallard and to various swine sequences.
My comment about the recency of the recombination is based on the lack of tiny changes in the sequences gsgs chose to compare with. If the new strain was old, then there would likely be several near matches with just 1 or 2 differences. But for the most part, either the whole segment is the same, zero differences, or completely different. This suggests that the new strain is, errrm, new.
Oh, and pigs don't fly, but mallards do, and it's the intercontinental shorebird and anseriform traffic that could be moving the european swine sequences around.
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April 27th, 2009, 06:37 PM
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Re: sequences at genbank !
Thanks WetDirt - now I wish I had taken the time to learn all this sequence stuff.
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April 27th, 2009, 06:41 PM
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Re: sequences at genbank !
does this mean we can stop worrying so much........?
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April 27th, 2009, 06:42 PM
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Re: sequences at genbank !
Quote:
Originally Posted by AlaskaDenise
Mama - would that suggest that the Mexican strain has undergone more mutation?
.
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Perhaps. It may also mean that California is just one amino acid mutation away from having a serious pandemic threat. Not a good time to get complacent.
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April 27th, 2009, 06:46 PM
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Re: sequences at genbank !
Quote:
Originally Posted by vinny
does this mean we can stop worrying so much........?
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No, it means that this is indeed a new strain and nobody is likely to have much immunity to it. And mamma's post says that it is likely to spread on surfaces better than most strains. But whether it has legs, that is, whether it can spread efficiently while maintaining its nastiness, is a different issue that we basically have to watch and wait to find out. And I'm not happy that nasal swabs might not be working as expected, which may mean a lot of cases are being missed. We know it makes a difference in birds which end you swab.
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April 27th, 2009, 06:46 PM
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Editor, Senior Moderator
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Re: sequences at genbank !
Quote:
Originally Posted by Mamabird
On the contrary, the fact that all of the California sequences have a Lysine at position 627 of the PB2 segment is fantastic news. Years of research would suggest that the California virus does not replicate well in the cooler temperatures of the upper respiratory system. Perhaps that is why we are seeing patients complain of nausea, vommiting and diarrhea. This thing replicates better in the digestive tract?
Suggests perhaps that the virus is more transmittable through touch and contaminated surfaces than coughs and sneezes. Might also suggest that the best way to detect the virus in a suspect patient is through anal swabs rather than nasal swabs. Virus loads in the intestines probably greater than the respiratory tract.
Now, what about the other sequences, particullary Mexico, where we have a large number of deaths. Is the E627K mutation present?
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So this discovery might suggest extra precautions by food handlers? That might also explain why areas with inadequate sanitation would spread the virus.
.
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April 27th, 2009, 06:55 PM
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Re: sequences at genbank !
Quote:
Originally Posted by AlaskaDenise
So this discovery might suggest extra precautions by food handlers? That might also explain why areas with inadequate sanitation would spread the virus.
.
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Yes, and that could also explain why the CDC has been recommending hand washing, and downplaying the usefulness of surgical masks and N95 respirators.
Previous pandemic viruses and our seasonal flu viruses have the E627K mutation from the wild state. From the posted sequences at GenBank, this virus does not. I am just thrilled with this news, but am trying to restrain myself as the H5N1 (Qinhai strain) was able to rid itself of the Lysine at 627.
We should also be pleased that the HA segment does not have multiple basic amino acids at the cleavage site. Based on existing research, this would suggest that we should not see rapid failure of multiple organs in severe human cases. All good news so far.
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April 27th, 2009, 06:59 PM
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Re: sequences at genbank !
it may be more similar in practical terms to Norovirus, which would explain why schools are being victims - except influenza will probably mutate far more - picking up polymorphisms from circulating seasonal H1N1.
Cruise ships, rest homes, etc. best beware.
What about NS1/92???
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April 27th, 2009, 07:02 PM
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Re: sequences at genbank !
What would this mean for produce from the area? I remember a green onion incident a while back. (ie: rinsed in contaminated water, hard to clean)
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April 27th, 2009, 07:03 PM
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Re: sequences at genbank !
Quote:
Originally Posted by AlaskaDenise
it may be more similar in practical terms to Norovirus, which would explain why schools are being victims - except influenza will probably mutate far more.
Cruise ships, rest homes, etc. best beware.
What about NS1/92???
.
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Exactly correct. Perhaps also, similar to Hepatitis. Maybe more likely to get this bug off of toilet tissue in public restrooms than from someone coughing on the subway.
I haven't an opportunity to get to NS1 yet, but the other good news confirmed by CDC testing is the sensitivity to Tamiflu. The NA segment does not show the mutations that allow the virus to resist Tamiflu. However, we have seen how this can quickly change. Judicial use of this antiviral is in order.
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April 27th, 2009, 07:05 PM
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Re: sequences at genbank !
Quote:
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What would this mean for produce from the area?
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Good point. Time to get out that bottle of organic produce wash.
It may also explain why Canada wants health exams for Mexican workers, but any food worker should now take extra precautions.
.
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April 27th, 2009, 07:21 PM
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Re: sequences at genbank !
I have commented in the 'Swine flu - basic information' and in response to question that I thought it very unlikely that the the H1N1 component of the seasonal flu shot would provide any worthwhile protection against our new pandemic candidate.
As the bulk of the antigenic sites are on HA & NA and of these HA is the more important I thought this radial phylogenic tree generated by BLASTing the HA in A/California/04/2009(H1N1) might be of interst. The HA is plotted against its 100 closest relatives in the database and while you will not be able to read the text I hope you will be able to see that A/California/04/2009(H1N1) (at the top with a yellow highlight) is 'out on a limb' even among its cousins. I will try and work out how to re do this with a few of those from this screen and A/Brisbane/59/2007 (H1N1) which is the seasonal vaccine H1 component and I expect to see it as being a long way of target.
The tree below has the vaccine selection A/Brisbane/59/2007 (H1N1) at the top, very much on its own, the next block are all very close matches and are the new sequences from CA & TX (no Mexican sequences yet but we are told they match CA/TX) and the bottom block are some of the closest matches in Genebank (4 swine & 1 avian,dates form 1999-2005, from the US and China).
Last edited by JJackson; April 28th, 2009 at 09:44 AM.
Reason: Added the second image
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April 27th, 2009, 07:22 PM
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Re: sequences at genbank !
Quote:
Originally Posted by AlaskaDenise
What about NS1/92???
.
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The NS segment of both the California and Texas sequence looks nothing like any H1N1 seasonal flu virus, 1918 pandemic virus, or H5N1 for that matter. Position 92 unremarkable with an aspartic acid (D) present.
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April 27th, 2009, 07:29 PM
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Re: sequences at genbank !
It really is a new strain. 
Don't know if that's good or bad.
Any history at all on aspartic acid at that location?
It could be the "Typhoid Mary" of the influenza world.
.
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April 27th, 2009, 07:33 PM
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Re: sequences at genbank !
Dare I suggest an epigenetic change?
Recent history has been showing epigenetic changes to immune systems of other species....something like this may be the cause.
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April 27th, 2009, 07:48 PM
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Re: sequences at genbank !
Quote:
Originally Posted by Mamabird
On the contrary, the fact that all of the California sequences have a Lysine at position 627 of the PB2 segment is fantastic news. Years of research would suggest that the California virus does not replicate well in the cooler temperatures of the upper respiratory system. Perhaps that is why we are seeing patients complain of nausea, vommiting and diarrhea. This thing replicates better in the digestive tract?
Suggests perhaps that the virus is more transmittable through touch and contaminated surfaces than coughs and sneezes. Might also suggest that the best way to detect the virus in a suspect patient is through anal swabs rather than nasal swabs. Virus loads in the intestines probably greater than the respiratory tract.
Now, what about the other sequences, particullary Mexico, where we have a large number of deaths. Is the E627K mutation present?
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E627K is mammalian (not a "mutation"). Swine is mammalian.
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April 27th, 2009, 07:50 PM
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Re: sequences at genbank !
Quote:
Originally Posted by vinny
does this mean we can stop worrying so much........?
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Only if you ignore 1918
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April 27th, 2009, 07:52 PM
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Re: sequences at genbank !
Quote:
Originally Posted by Mamabird
Yes, and that could also explain why the CDC has been recommending hand washing, and downplaying the usefulness of surgical masks and N95 respirators.
Previous pandemic viruses and our seasonal flu viruses have the E627K mutation from the wild state. From the posted sequences at GenBank, this virus does not. I am just thrilled with this news, but am trying to restrain myself as the H5N1 (Qinhai strain) was able to rid itself of the Lysine at 627.
We should also be pleased that the HA segment does not have multiple basic amino acids at the cleavage site. Based on existing research, this would suggest that we should not see rapid failure of multiple organs in severe human cases. All good news so far.
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1918 didn't have a polybasic cleavage site.
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April 27th, 2009, 07:57 PM
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Re: sequences at genbank !
Quote:
Originally Posted by AlaskaDenise
It really is a new strain.
Don't know if that's good or bad.
Any history at all on aspartic acid at that location?
It could be the "Typhoid Mary" of the influenza world.
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Pig virus with Aspartic Acid (D) at position 92 of NS1 have been found to be less virulent than with Glutamic Acid (E) at that position. However, many H5N1 viruses have Aspartic Acid, so there are likely multiple factors at play.
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Disclaimers:
The reader is responsible for discerning the validity, factuality or implications of information posted here, be it fictional or based on real events. Moderators on this forum make every effort to review the material posted on this site however, it is not realistically possible for our staff to manually review each post.
The content of posts on this site, including but not limited to links to other web sites, are the expressed opinion of the original authors or posters and are not endorsed by, or representative of the opinions of, the owners or administration of this website. The posts on this website are the opinion of the specific author or poster and should not be construed as statements of advice or factual information.
Not all posts on this website are intended as truthful or factual assertion by their authors. NO posts on this website should be considered factual information on face value alone. Users are encouraged to USE DISCERNMENT and do their own follow up research while reading and posting on this website. FluTrackers.com Inc. reserves the right to make changes to, corrections and/or remove entirely at any time posts made on this website without notice. In addition, FluTrackers.com Inc. disclaims any and all liability for damages incurred directly or indirectly as a result of a post on this website.
This site is provided "as is" without warranty of any kind, either expressed or implied. You should not assume that this site is error-free or that it will be suitable for the particular purpose which you have in mind when using it. In no event shall FluTrackers.com Inc. be liable for any special, incidental, indirect or consequential damages of any kind, or any damages whatsoever, including, without limitation, those resulting from loss of use, data or profits, whether or not advised of the possibility of damage, and on any theory of liability, arising out of or in connection with the use or performance of this site or other documents which are referenced by or linked to this site.
Finally, FluTrackers.com Inc. reserves the right to delete, correct, or make changes to any post on this website without notice at any time for any reason.
Fair Use Notice:
This site may contain copyrighted material the use of which has not always been specifically authorized by the copyright owner. Users may make such material available in an effort to advance awareness and understanding of issues relating to public health, civil rights, economics, individual rights, international affairs, liberty, science & technology, etc. We believe this constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C.Section 107, the material on this site is distributed to those who have expressed a prior interest in receiving the included information for research and educational purposes.
In accordance with industry accepted best practices we ask that users limit their copy / paste of copyrighted material to the relevant portions of the article you wish to discuss and no more than 1 paragraph, and in no case more than 50% of the source material provide a link back to the original article and provide your original comments / criticism in your post with the article. Please remember you are responsible for what you post on the internet and you could be sued by the original copyright holder if you do not honor these rules.
If you are a legal copyright holder or a designated agent for such and you believe a post on this website falls outside the boundaries of "Fair Use" and legitimately infringes on yours or your clients copyright
we may be contacted concerning copyright matters at:
FluTrackers.com Inc.
c/o Sharon Sanders
1676 Hibiscus Avenue
Winter Park, Florida 32789
Phone: 407-745-1513
E-Mail: flutrackers@earthlink.net
In accordance with section 512 of the U.S. Copyright Act our contact information has been registered with the United States Copyright Office. "Safe Harbor" noticing procedures as outlined in the DMCA apply to this website concerning all 3rd party posts published herein.
If notice is given of an alleged copyright violation we will act expeditiously to remove or disable access to the material(s) in question.
All 3rd party material posted on this website is the copyright of the respective owners / authors. FluTrackers.com Inc. makes no claim of copyright on such material.
For more information please visit:
http://www.law.cornell.edu/uscode/17/107.shtml
Please be aware any communications sent complaining about a post on this website may be posted publicly at the discretion of the administration.
FluTrackers Does Not Provide Any Medical Advice:
FluTrackers, Inc. does not provide medical advice. Information on this web site is collected from various internet resources, and the FluTrackers board of directors makes no warranty to the safety, efficacy, correctness or completeness of the information posted on this site by any author or poster.
The information collated here is for instructional and/or discussion purposes only and is NOT intended to diagnose or treat any disease, illness, or other medical condition. Every individual reader or poster should seek advice from their personal physician/healthcare practitioner before considering or using any interventions that are discussed on this website.
By continuing to access this website you agree to consult your personal physican before using any interventions posted on this website, and you agree to hold harmless FluTrackers.com Inc., the board of directors, the members, and all authors and posters for any effects from use of any medication, supplement, vitamin or other substance, device, intervention, etc. mentioned in posts on this website, or other internet venues referenced in posts on this website.
By using and/or accessing this site, either passively or actively, you are agreeing to all of the above conditions. Also, by using and/or accessing this site, either passively or actively, you agree to conduct all business and legal affairs related to this website in the jurisdiction of Flutrackers.com Inc. which is registered in Central Florida, USA.
These Disclaimers are subject to change at anytime.
Email the Webmaster with questions or comments about this site at flutrackers@earthlink.net
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