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The Oaxacan Gerardo Ju?rez Adri?n Avenda?o received the laboratory sample of the first woman who died from influenza humana

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  • The Oaxacan Gerardo Ju?rez Adri?n Avenda?o received the laboratory sample of the first woman who died from influenza humana



    21-Apr-2010
    Discarded exaggeration of measures
    Patricia Briseno
    The Oaxacan Gerardo Ju?rez Adri?n Avenda?o received the laboratory sample of the first woman who died from influenza humana

    OAXACA, Oax .- Adri?n Ju?rez Gerardo Avenda?o, a master of molecular biomedicine National Polytechnic Institute (IPN), received the laboratory sample of Adela, first woman who died from influenza A virus H1N1, which last year had humanity in check.
    The scientist found in the clinical laboratory, located in the historic center of Oaxaca City, which was a coronavirus (which is of extraordinary dimensions) similar to Severe Acute Respiratory Syndrome (SARS), recorded seven years ago in Asia.
    "Seeing for the first time, I was afraid for its high aggressiveness and virulence, and what could happen to the patient, according to information from specialized texts," he said in an interview.
    A year away, the professor of the Faculty of Chemistry at the Autonomous University Benito Juarez of Oaxaca (UABJO) considered that the measures taken by the Mexican government to deal with influenza A H1N1 were successful. "In no way was a false alarm," he said.
    Juarez Avendano recalled that two days of the Easter holidays of 2009, devoted to amplify images of coronavirus, until a portion of their DNA and, according to molecular biology, he found it belonged to the H1N1 strain, and they were produced by mixing the genes of the swine flu and another that affects humans.
    The finding was a chance "after laboratory tests requested by the Directorate of Civil Hospital of Infectious Diseases Health Services of Oaxaca (SSO) to find at first bacteria, then decided to find a virus in the patient sample 39.
    The teacher explained that biomedical molecular size of the molecules was what it was revealed that a new virus, known until then-just in books.
    At first I thought it was of atypical pneumonia known as SARS, so did the wake-up call to health services.
    Gerardo Adrian is a chemical biologist, was born in Santiago Telixtlahuaca, a municipality located 32 kilometers from the capital of Oaxaca, has 47 years, and with his young team is studying molecular biology applied to clinical diagnosis, a laboratory of your property.
    He said one of the joys that his discovery has reunited with former teammates from IPN and receive invitations to participate in seminars and conferences.
    He stressed that the Polytechnic Institute invited him to participate in the doctoral research dedicated to influenza A H1N1, however, still value their participation.
    The Oaxacan alerted the state health services, who after listening, sent surveys to the Institute of Epidemiological Diagnosis and Reference in Mexico City and then to Canada.
    "I was not prepared to isolate the virus, that would have been ideal, extracting RNA, its essential part," the scientist.

  • #2
    Re: The Oaxacan Gerardo Ju?rez Adri?n Avenda?o received the laboratory sample of the first woman who died from influenza humana

    Tough to believe it has already been a year.

    This article does give some indication of why Oaxacan authorities thought they were finding a coronavirus in the woman in question. The translation above is not quite clear, but I don't think any actual lab test returned a positive result for coronavirus. I think someone with a not-so-good understand of virology assumed that all severe respiratory illness is caused by coronaviruses (which couldn't be further from the truth) as noted by the comment in the above article that H1N1 is a type of coronavirus, which is clearly false. The article specifically quotes the scientist as saying he was not prepared to isolate the virus in question.

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    • #3
      Re: The Oaxacan Gerardo Ju?rez Adri?n Avenda?o received the laboratory sample of the first woman who died from influenza humana

      The following Mexican source Spanish language article provides another good summary of this event. Notably, this article still, one year later, believes that bird flu and SARS are the same disease. It also gives more information as to the occupation of this woman.



      One year of Human Influenza A/H1N1; chronology of the pandemic of S. XXI XXI
      El primer caso demostrados con A/H1N1 fue del 10 de marzo, de un paciente que fue atendido en el Instituto Nacional de Enfermedades Respiratorias, y por ello el caso del ni?o Edgar Hern?ndez no fue de ninguna manera el caso cero, afirm? el titular de Salud. The first H1N1 case was demonstrated by March 10 of a patient who was treated at the National Institute of Respiratory Diseases, and therefore the case of the boy Edgar Hernandez was by no means the case zero, said the owner of Health.




      Lun, 19/04/2010 - 15:37 Mon, 19/04/2010 - 15:37
      Ciudad de M?xico.- El fallecimiento de Adela Mar?a Guti?rrez Cruz, de 39 a?os, quien trabajaba como encuestadora del Servicio de Administraci?n Tributaria (SAT), prendi? la alerta mundial sobre la presencia de un nuevo virus que, en ese momento, se consideraba ?primo hermano de la influenza aviar (SARS)?, porque evolucionaba muy r?pido, resultaba altamente contagioso y mataba a gente joven. Mexico City .- The death of Adela Maria Gutierrez Cruz, 39, who worked as a pollster the Tax Administration Service (SAT), turned on the global alert about the presence of a new virus that, at the time, was considered " cousin of avian influenza (SARS) ", because evolving very fast, it was highly contagious and killed young people.

      Guti?rrez Cruz, de acuerdo al Centro Nacional de Vigilancia Epidemiol?gica y Control de Enfermedades, present? s?ntomas el 4 de abril y hacia el d?a 12 de ese mes ingres? al Hospital Aurelio Valdivieso, ubicado en Oaxaca, con un cuadro de neumon?a grave. Gutierrez Cruz, according to the National Center of Epidemiological Surveillance and Disease Control, developed symptoms on 4 April to the 12th of that month entered the Aurelio Valdivieso Hospital, located in Oaxaca, with a picture of severe pneumonia. Finalmente falleci? el 13 de abril en aquella regi?n. Finally died on April 13 in that region.

      Se trata de un caso importante dentro del aniversario de aparici?n del virus A/H1N1 porque alert? al mundo sobre la primera pandemia del siglo XXI que caus? ?p?nico y terror? al grado de que M?xico y sus connacionales sufrieron todo tipo de discriminaciones, que fueron desde el cierre unilateral de fronteras de ciertos pa?ses, aislamientos forzados, y que la venta nacional y la exportaci?n de la carne de puerco cayeran en 90 por ciento. This is an important event in the anniversary of the appearance of H1N1 virus because it alerted the world to the first pandemic of the XXI century that caused "panic and terror" to the extent that Mexico and its nationals suffered all kinds of discrimination, which were from the unilateral closure of borders in certain countries, forced isolation, and domestic sale and export of pork fell by 90 percent.

      Sin embargo, como reconoci? en entrevista el secretario de Salud, Jos? ?ngel C?rdova Villalobos, el caso de Oaxaca en absoluto se trata de primer contagio ni de la primera v?ctima mortal a causa del Virus de la Influenza Humana A/H1N1, de origen porcino. However, as acknowledged in an interview with Health Secretary Jose Angel Cordova Villalobos, the case of Oaxaca is absolutely first transmission or the first fatality from the virus of the H1N1 human influenza, porcine.

      Y lo mismo sucede con el ni?o Edgar Hern?ndez, que sobrevivi? al mal. The same happens with the child Edgar Hernandez, who survived the evil. Tampoco se trata del caso cero de contagio, aun cuando, el infante sufri? como otros habitantes de la localidad La Gloria, municipio de Perote, Veracruz, un brote anormal infecciones respiratorias agudas durante marzo y abril. Nor is it the case of transmission zero, even if the infant suffered as other inhabitants of La Gloria, a town of Perote, Veracruz, an abnormal outbreak acute respiratory infections during March and April.

      ?Ya despu?s en retrospectiva se recuperaron las muestras y la informaci?n de algunos casos anteriores, incluso ahora podemos decir con seguridad que el primer caso demostrados con A/H1N1 fue del 10 de marzo, de un paciente que fue atendido en el Instituto Nacional de Enfermedades Respiratorias, y por ello el caso de Edgar no fue de ninguna manera el caso cero?, aclar? C?rdova Villalobos. "Already back then recovered samples and information from some previous cases, even now we can safely say that the first H1N1 case was demonstrated by March 10 of a patient who was treated at the National Institute of Diseases respiratory, and therefore if Edgar was not the case any way scratch, "added Cordova Villalobos.

      Con respecto a la primera v?ctima mortal, la Comisi?n Nacional de Arbitraje M?dico reporta a una mujer soltera, de 24 a?os, que falleci? el 10 de abril de 2009, en el Distrito Federal. With regard to the first fatality, the National Medical Arbitration Commission reports to a single woman, aged 24, who died on April 10, 2009, in the Federal District. Hasta el momento ninguna autoridad ha podido definir los antecedentes de dicha persona pese a los constantes requerimientos de informaci?n. So far no authority has been able to define the background of that person despite the constant requests for information.

      Hacia el 17 abril de 2009, los Centro de Control y de la Prevenci?n de Enfermedades (CDC, por su siglas en ingl?s), de Estados Unidos dieron a conocer de ?manera informal a las autoridades sanitarias? de M?xico, que el 28 y 30 de marzo se registraron en el condado de San Diego y el Imperial dos casos de ni?os, de 9 y 8 a?os, con influenza y que los estudios de laboratorio suger?an que se trataba de un nuevo virus, de una nueva cepa, de la Influenza tipo A, subtipo H1N1. By 17 April 2009, the Center for Disease Control and Prevention (CDC, for its acronym in English), United States themselves known "informally to the health authorities" in Mexico, 28 and 30 March were recorded in the county of San Diego and Imperial two cases of children, 9 and 8 years, with influenza and laboratory studies suggested that this was a new virus, a new strain of Influenza A, subtype H1N1. ?Esto representaba un hallazgo inesperado?. "This was an unexpected finding."

      El 21 abril, M?xico manda al laboratorio nacional de Canad? 51 muestras, incluidas las de los casos de Perote y de Oaxaca, y de pacientes del INER, para corroborar si alguna era id?ntica a la nueva cepa. On 21 April, Mexico sent to Canada's national laboratory 51 samples, including cases of Perote and Oaxaca, and INER patients to confirm if any were identical to the new strain.

      El 23 abril, el laboratorio de Canad? inform? v?a telef?nica que entre las 51 muestras enviadas por M?xico, 17 resultaban positivas e id?nticas a los casos aislados de esta cepa ?con potencial pand?mico?, por lo que al secretario de Salud se traslad? a la Residencia Oficial de los Pinos a informar al presidente Felipe Calder?n sobre dicho hallazgo y en ese momento se convoc? al gabinete legal y ampliado. On 23 April, Canada reported laboratory by telephone that among the 51 samples submitted by Mexico, 17 were positive and identical to the isolated cases of this strain "with pandemic potential," as Secretary of Health moved to the Residence Pines Officer to report to President Felipe Calderon on this finding and at that time called the law firm and enlarged.

      Al filo de las 11 de la noche, del 23 de abril, C?rdova Villalobos anunci? la suspensi?n de clases en el Distrito Federal y el Estado de M?xico, en todos sus niveles. The Edge of 11 pm, April 23, C?rdova Villalobos announced the suspension of classes in the Federal District and Mexico State, at all levels.

      De inmediato comenzaron las cancelaciones de vuelo, el Aeropuerto Internacional de la Ciudad de M?xico dej? de percibir del 24 de abril al 11 de mayo, alrededor de 200 millones de pesos por concepto de Tarifa de Uso de Aeropuerto, debido a la cancelaci?n de 3 mil 59 vuelos. They immediately began flight cancellations, the International Airport of Mexico City failed to receive from 24 April to 11 May, about 200 million pesos worth of airport usage fees, due to the cancellation of 3 thousand 59 flights.

      Para entonces, el ramo hotelero perdi? un 70% de ocupaci?n en 2009, y en el sector turismo y comercio se perdieron 43 mil 701 empleos formales entre abril y mayo. By then, the hotel sector lost 70% occupancy in 2009, and tourism and trade sector lost 701 43 thousand formal jobs between April and May. Las perdidas por turismo y comercio se estimaron entre 8 mil millones de pesos y 13 mil 600 millones de pesos. The lost tourism and trade were estimated at 8 billion dollars and 13 thousand 600 million pesos.

      El 24 abril, en los Pinos, la Secretar?a de Salud inform? que se trataba de un ?virus de origen eruoasi?tico? que ya hab?a causado la muerte confirmada de 20 personas, que resultaba ?altamente contagioso, mortal y con propiedades pand?micas?. On 24 April, in the Pines, the Ministry of Health reported that it was a "virus eruoasi?tico source" who had already killed 20 people confirmed that it was "highly contagious, deadly pandemic properties." Sin embargo se contaba con antivirales que curaban. However, it had cured antiviral.

      El 26 abril, en un mensaje a la naci?n el presidente Felipe Calder?n inform? que hasta ese momento se ten?a registrados mil 384 casos de personas que registraban neumon?a y 81 muertos. On 26 April, in an address to the nation President Felipe Calderon said until that time had 384 thousand registered cases of people who registered pneumonia and 81 deaths. A partir de entonces, la SSA comenz? toda una danza de cifras, ya que ese mismo d?a la SSA elev? a 103 los decesos ya mil 614 los contagios. Since then, SSA began a full dance numbers, since that same day, the SSA's fatalities rose to 103 and 614 thousand new infections.

      El 27 abril, OMS eleva a fase 4 la contingencia. On 27 April, WHO Phase 4 amounts to the contingency. Para entonces ya hab?a 149 decesos, pero ?s?lo en 20 casos se tiene la evidencia etiol?gica?. By now there were 149 deaths, but "only 20 cases have etiological evidence." Ese mismo d?a la SSA orden? a nivel nacional la suspensi?n de clases y de guarder?as hasta el 6 de mayo. That same day the national SSA ordered the suspension of classes and child care until 6 May.

      El 29 abril, C?rdova orden? la suspensi?n de actividades en la administraci?n p?blica federal, as? como de los trabajos y de los servicios no esenciales de los sectores productivos del 1 al 5 de mayo, a fin de ?evitar en lo posible una pandemia? de influenza porcina. On April 29, C?rdova ordered the suspension of activities in the federal public administration, as well as work and non-essential services of the productive sectors of 1 to 5 May, in order to "avoid, where possible pandemic" of swine influenza.

      Se cancelan 600 actos culturales, deportivos y espect?culos p?blicos, asimismo se cerraron y se restringi? el servicio de restaurantes s?lo para llevar. 600 cultural events were canceled, sporting and public events also were closed and service was restricted only to bring restaurants. Hasta las iglesias dejaron de tener misa dominical y los pocos que sal?an lo hac?an con cubrebocas. Even the churches have failed to Sunday Mass and the few who came did so with masks.

      La Organizaci?n Mundial de la Salud inform? que el brote epid?mico de la influenza porcina afecta ya a varios pa?ses del mundo, con alrededor de 79 casos confirmados. The World Health Organization said the outbreak of swine influenza is already affecting several countries in the world, with about 79 confirmed cases.

      El 29 abril, la OMS declara la emergencia en fase 5. On 29 April, WHO declared the emergency phase 5. ?El virus se trasmite de persona a persona en al menos dos pa?ses de una regi?n de la OMS. "The virus is transmitted from person to person in at least two countries in a region of WHO. La pandemia es eminente?. The pandemic is imminent. " Hacia el 13 de mayo, la OMS ten?a notificado oficialmente 5 mil728 casos de infecci?n en 33 pa?ses. By 13 May, WHO had 5 mil728 officially reported cases of infection in 33 countries.

      El 8 de mayo la Organizaci?n Panamericana de la Salud defendi? a M?xico que ya lo acusaban d haber exagerado con un virus no tan letal, con el argumento de que si no se hubiesen tomado las medidas de distanciamiento social habr?an muerto 8 mil 605 personas; 30 mil hospitalizaciones y alrededor de 4.5 millones de consultas ambulatorias. On May 8 the Pan American Health Organization defended Mexico that accused him and d have exaggerated a virus so lethal, arguing that if they had taken the social distancing measures would have died 8 thousand 605 people, 30 thousand hospitalizations and about 4.5 million outpatient visits.

      El 11 de junio, la OMS Organizaci?n Mundial de la Salud decret? la fase seis, la alerta m?xima y advirti? que "circular? por todo el mundo durante un a?o o dos", aunque de manera "moderada". On 11 June, WHO World Health Organization declared the phase six, the highest alert and warned that "circulate throughout the world for a year or two," albeit "moderate." Esta fue acusada de utilizar a M?xico para beneficiar a la industria farmac?utica. This was accused of using to Mexico to benefit the pharmaceutical industry.

      M?xico ha tenido por lo menos tres picos de contagio importantes: el primero tuvo lugar en el centro del pa?s, entre abril y mayo; el segundo en junio, julio y agosto en el sureste, y el tercero que empez? desde el 15 de septiembre, teniendo su pico m?s alto en octubre (42.8 por ciento del total de los casos registrado). Mexico has had at least three major transmission peaks: the first took place in the center of the country between April and May, the second in June, July and August in the southeast, and the third that started from 15 September having its peak in October (42.8 percent of total recorded cases).

      Hasta el 14 de abril del 2010, la SSA reporta 72 mil 462 casos confirmados y mil 185 defunciones. Until April 14, 2010, the SSA reports 72 thousand 462 thousand 185 confirmed cases and deaths. Ya se est? por cumplir con la meta de aplicar 28 millones de vacunas A/H1N1. It is to meet the goal of implementing 28 million H1N1 vaccines.

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