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  • Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus-reporting error

    Obviously, S. suis infection is a high possibility here as well.

    The mention of 4 human infections toward the end of the article makes me suspect that this might be S. suis.



    Archive Number 20100526.1751
    Published Date 26-MAY-2010
    Subject PRO/AH/EDR> Porcine reprod. & resp. syndrome - Viet Nam (02), human fatality susp.

    PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME - VIET NAM (02), HUMAN
    FATALITY SUSPECTED
    ************************************************** *************************************
    A ProMED-mail post
    <HTTP: www.promedmail.org="">
    ProMED-mail is a program of the
    International Society for Infectious Diseases
    <HTTP: www.isid.org="">

    Date: Wed 26 May 2010
    Source: VietnamNet Bridge [edited]
    <HTTP: pig-disease-feared-to-claim-first-fatality-912419="" 201005="" social="" english.vietnamnet.vn="">


    Pig disease feared to claim 1st fatality
    ----------------------------------------
    Porcine reproductive and respiratory syndrome (PRRS), commonly dubbed
    blue-ear disease, is suspected as the culprit behind the death of a
    man in the central province of Quang Ngai on Monday [24 May 2010].

    Nguyen Xuan Men, deputy director of the provincial Department of
    Health confirmed with the online newspaper Vnexpress that the young
    man was suspected to be the 1st to succumb to the deadly pig disease
    that is spreading to pig herds in the north. According to Men, the
    young man suffered from diarrhea, high fever, convulsion, and skin
    hemorrhage after eating fresh pig blood pudding. He was not
    hospitalized in time and lost consciousness.

    The man, who was transferred to the Central Hospital of Hue from
    Quang Ngai, died on Monday. Health workers immediately disinfected
    where he was living and examined people who had been in contact with
    the deceased. Health workers said the virus of PRRS has a particular
    affinity for macrophages particularly those found in the lung.
    Macrophages are part of the body defenses. Those present in the lung
    are called alveolar macrophages. They ingest and remove invading
    bacteria and viruses but not in the case of the PRRS virus. Instead,
    the virus multiplies inside them producing more viruses and kills the
    macrophages.

    Once it has entered a herd PRRS virus tends to remain present and
    active indefinitely. The fatality rate is at 7 percent; thus, it can
    do harm if patients are not timely hospitalized.

    The National Department of Health reported that no new blue ear
    disease outbreaks were reported in recent days. However, the epidemic
    remained active in 15 provinces nationwide, mostly in northern
    provinces including Hanoi. Since April this year, 4 positive [human?]
    cases of porcine reproductive and respiratory syndrome have been
    detected.

    --
    Communicated by:
    Charles Ortleb
    <RUBICONMEDIA@YAHOO.COM>

    [Initially reported by Viet Nam to the OIE as starting in March 2007,
    PRRS was declared endemic in February 2008. Some investigators are of
    the opinion that it had been circulating in the region since 1999
    (for more detailed information, see: Porcine reprod. & resp. syndrome
    - Viet Nam 20100414.1206).

    Porcine reproductive and respiratory syndrome (PRRS) is characterised
    by reproductive failure of sows and respiratory problems of piglets
    and growing pigs. The disease is caused by porcine reproductive and
    respiratory disease (PRRS) virus, a virus classified as a member of
    the order _Nidovirales_, family _Arteriviridae_, genus _Arterivirus_.
    The primary target cell of the virus is the alveolar macrophage of
    the pig. 2 major antigenic types of the virus exist, the European and
    the American type.

    The virus is primarily transmitted via infected pigs but also by
    faeces, urine, semen and fomites. PRRS virus infection occurs in most
    major pig-producing areas throughout the world. The reproductive
    failure is characterised by infertility, late fetal mummification,
    abortions, stillbirths, and the birth of weak piglets that often die
    soon after birth from respiratory disease and secondary infections.
    Older pigs may demonstrate mild signs of respiratory disease, usually
    complicated by secondary infections. No other species are known to be
    naturally infected with PRRSV. Virological diagnosis of PRRS virus
    infection is difficult. For further information readers are referred
    to chapter 2.8.7 in the O.i.E. Manual
    (<HTTP: 2.08.07_prrs.pdf="" pdf="" 2008="" mmanual="" normes="" eng="" www.oie.int="">).

    There are no previous records of human cases of PPR virus infection
    at least to this moderator's knowledge. Indeed none of the viruses
    classified in the family _Arteriviridae_ are known to be natural
    human pathogens. Therefore this Vietnamese report must regarded with
    caution in the absence of confirmatory laboratory diagnosis.
    Nonetheless the nature of the exposure (consumption of amounts of
    fresh (uncooked?) pig blood is exceptional. Furthermore the outcome
    of infection in pigs is in general less dramatic than that described
    in the case of this unfortunate man.

    Confirmatory diagnosis is awaited. If this report is authenticated it
    is a very serious development in view of the global occurrence of the
    PRRS in pigs and the genetic lability of the virus. - Mod.CP]</HTTP:></RUBICONMEDIA@YAHOO.COM></HTTP:></HTTP:></HTTP:>
    Last edited by Treyfish; May 28, 2010, 07:13 PM. Reason: new reports

  • #2
    Re: Vietnam: Possible human fatal infection with PRRS virus

    Here is the original article. Perhaps the ProMED post should have been labelled as "heavily edited". I am leaning toward S. suis on this one.



    Pig disease feared to claim first fatality
    Last update 11:46, Wednesday, 26/05/2010 (GMT+7)
    ,
    VietNamNet Bridge ? Porcine Reproductive and Respiratory Syndrome (PRRS), commonly dubbed blue-ear disease, is suspected as the culprit behind the death of a man in the central province of Quang Ngai on Monday.

    Blue-ear disease spreads in northern, central regions

    Blue-ear pig disease confuses the market

    Nguyen Xuan Men, deputy director of the provincial Department of Health; confirmed with the online newspaper Vnexpress that the young man was suspected to be the first to succumb to the deadly pig disease that is spreading to pig herds in the north.

    According to Men, the young man suffered from diarrhea, high fever, convulsion, and skin hemorrhage after eating fresh pig blood pudding. He was not hospitalized in time and lost consciousness.

    The man, who was transferred to the Central Hospital of Hue from Quang Ngai, died on Monday.

    Health workers immediately disinfected where he was living and examined people who had been in contact with the deceased. Health workers said the virus of PRRS has a particular affinity for the macrophages particularly those found in the lung.

    Macrophages are part of the body defenses. Those present in the lung are called alveolar macrophages. They ingest and remove invading bacteria and viruses but not in the case of the PRRS virus. Instead, the virus multiplies inside them producing more viruses and kills the macrophages.

    Once it has entered a herd the virus tends to remain present and active indefinitely. The fatality rate is at 7%, thus, it can do harm if patients are not timely hospitalized.

    The National Department of Health reported that no new blue ear disease outbreaks were reported in recent days. However, the epidemic remained active in 15 provinces nationwide, mostly in northern provinces including Hanoi.

    Since April this year, four positive cases of Porcine Reproductive and Respiratory Syndrome have been detected.

    VietNamNet/SGT

    Comment


    • #3
      Re: Vietnam: Possible human fatal infection with PRRS virus

      Treyfish has been posting updates on a large S. suis outbreak ongoing in Vietnam. The last posts on that are here:



      Notably, infection of pigs with PRRS virus has apparently been linked to increased susceptibility to infection with S. suis.

      Comment


      • #4
        Re: Vietnam: Possible human fatal infection with PRRS virus

        6:32 AM, 27/05/2010
        Quang Ngai: There are no conclusions about the cause of death from suspected swine Streptococcus



        Afternoon 26 / 5, Dr. Nguyen Xuan Men - Deputy Director of Quang Ngai Department of Health said the Department had written to directors of Hue Central Hospital confirmed causes of death of Mr Bui Van Nhuan (37 years old ) suspected swine streptococcus bacteria in the ward chief Lo, Quang Ngai city.

        In the last few days, some mass media that Mr. Bui Van Nhuan death by suspected swine Streptococcus. This has to affect the psychology of people and communities.

        Previous information on, pending the conclusion of the Central Hospital in Hue, Quang Ngai province, the health sector has been assigned to the Center of preventive medicine in promoting active communities on the fields of prevention, such as pigs should not be unknown origin, not given away slaughter and consumption of the pigs died of unknown causes, and recommended people not eat more soup, pig heart or undercooked pork, source unknown Original. /. http://vovnews.vn/Home/Quang-Ngai-Ch...105/144928.vov
        CSI:WORLD http://swineflumagazine.blogspot.com/

        treyfish2004@yahoo.com

        Comment


        • #5
          Pig disease feared to claim first fatality

          Porcine Reproductive and Respiratory Syndrome (PRRS), commonly dubbed blue-ear disease, is suspected as the culprit behind the death of a man in the central province of Quang Ngai on Monday.

          Nguyen Xuan Men, deputy director of the provincial Department of Health; confirmed with the online newspaper Vnexpress that the young man was suspected to be the first to succumb to the deadly pig disease that is spreading to pig herds in the north.


          (read more, link)

          Comment


          • #6
            Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus - S. suis more likely

            There are two pathogens likely involved in this incident. PRRS is caused by a vrius, and affects only pigs. S. suis is a bacterium, and spreads from pigs to humans. Vietnam has reported at least 4 fatal S. suis infections in central Vietnam in the past few days, and this could be the first one in North Vietnam. Human infections with the PRRS virus are previously unheard of. PRRS infections in pigs do increase the likelihood that the pig will carry S. suis, so it isn't entirely incorrect to link the man's death with that virus, but the man's death was likely not caused by himself being infected with the virus. Several other articles have described this in more detail (such as the ones in http://www.flutrackers.com/forum/sho...218#post357218 )

            Since the article itself states that the disease has a 7&#37; fatality rate, it is almost certain that the disease that is suspected to have killed this man is S. suis, as it would be impossible to calculate the fatality rate of a virus if this was the first human case.

            I believe the article that ProMED is quoting is in error.

            Comment


            • #7
              Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus

              Porcine Reproductive and Respiratory Syndrome - Vietnam, Human Infection Debated (from ProMedMail.org, extract, edited)

              [Source: ProMedMail.org, full text (LINK). Extract, edited.]

              Archive Number 20100528.1778
              Published Date 28-MAY-2010
              Subjec PRO/AH Porcine reprod. & resp. syndrome - Viet Nam (04): RFI

              PORCINE REPRODUCTIVE & RESPIRATORY SYNDROME - VIET NAM (04): HUMAN INFECTION DEBATED
              ************************************************** *************************
              A ProMED-mail post <http://www.promedmail.org>
              ProMED-mail is a program of the International Society for Infectious Diseases <http://www.isid.org>

              Date: Fri 28 May 2010
              From: Trevor Drew <t.w.drew@vla.defra.gsi.gov.uk> [edited]

              Re: ProMED-mail Porcine reprod. & resp. syndrome - Viet Nam (02), human fatality suspected 20100526.1751
              ----------------------------------------------------------------------
              I would like to endorse the views expressed by Dr Kelly Lager (ProMED-mail posting no. 20100527.1762), concerning the supposed involvement of PRRSV in human deaths in Viet Nam. As a pig virologist who has spent many years studying this virus, both in Europe and in Asia, I am also concerned about the claims made by a Vietnamese medical official, that PRRSV was causative in this and other cases in that country. There has been no accompanying scientific evidence to support such a claim and, without such evidence, these claims only serve to generate significant disruption and possibly panic within the population of Viet Nam and beyond. Also, quite apart from the potential damage to the larger-scale pig production in the region, pigs are a significant part of the rural economy and a major protein source for the country - constituting more than 70 percent of the total meat production of the region.

              Pigs are also part of the societal fabric, often acting as a form of savings and additional income at times of hardship, school fees, etc. So any associated panic could have significant sociological consequences in the longer term. As Kelly Larger says, there are far more reasonable explanations for this small number of deaths.

              Anyone who has been studying this virus must be concerned about the increasing diversity exhibited by this virus, particularly in Asia, where the methods of production and numbers of pigs seem to provide optimal conditions for its evolution. And, considering PRRSV is a virus relatively new to pigs, having been known to science only for the last 20 years, it would be rash to totally dismiss the possibility of a jump to another species, including man. But until this and other cases are carefully investigated, I would suggest it is the duty of all scientists and communicators of science to present such information in a responsible way.

              I raise the question of whether the inclusion of the caveat within the initial and subsequent ProMED reports was sufficient, or whether the opinion of a PRRSV expert should have been sought and published alongside the original report.

              --
              Prof Trevor Drew PhD, MSc, CBiol, MSB
              Head of Virology Department
              Head of Statutory and Exotic Virus Programme
              Chair, VLA Academic Board
              OIE Reference Expert for CSF, BVD & EVA
              Veterinary Laboratories Agency (Weybridge)
              New Haw, Addlestone
              Surrey KT15 3NB
              UK
              <t.w.drew@vla.defra.gsi.gov.uk>
              <http://www.vla.gov.uk/>

              [Editor's comment: We appreciate Prof. Drew's views as an expert on this topic and thank him for this contribution. ProMED sees its primary role as a provider of early warnings of emerging disease outbreaks. Thus we need to balance the requirement for rapid reporting, needed to recognize and combat an outbreak, with the need for cautious interpretation of incomplete information and deliberation among experts. We decided to pass along this news story (which was already widely available on the Internet and in the public domain) with our view that the occurrence of PRRS in humans was unproven and indeed unlikely. Part of our role is to temper media sensationalism with rational context.

              As Prof. Drew states however, species jumps can and do occur unexpectedly. Such species jumps are an important source of newly emerging infectious diseases and a major reason for ProMED's emphasis on "one medicine" in our reporting. We also recognize our obligation to provide a forum for informed discussion and to present further evidence, which we eagerly await, as it becomes available. - Ed.LM]

              [see also:
              Porcine reprod. & resp. syndrome - Viet Nam (03): human fatality
              debated 20100527.1762
              Porcine reprod. & resp. syndrome - Viet Nam (02), human fatality
              suspected 20100526.1751
              Porcine reprod. & resp. syndrome - Viet Nam 20100414.1206
              Streptococcus suis, human - Viet Nam 20100430.1398
              Streptococcus suis, human - Viet Nam 20100503.1432
              2007
              ----
              Streptococcus suis, human, porcine & PRRS - Viet Nam 20070726.2403]
              ...................................arn/mj/lm
              (...)
              -
              -----

              Comment


              • #8
                Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus

                It would be nice if some Vietnamese official would contact ProMED with more information. I don't really think anyone really suspected PRRS virus in the decased human; I think it was likely a reporting error.



                Archive Number 20100527.1762
                Published Date 27-MAY-2010
                Subject PRO/AH> Porcine reprod. & resp. syndrome - Viet Nam (03): human infection debated

                PORCINE REPRODUCTIVE & RESPIRATORY SYNDROME - VIET NAM (03): HUMAN
                INFECTION DEBATED
                ***********************************************
                A ProMED-mail post
                <http://www.promedmail.org>
                ProMED-mail is a program of the
                International Society for Infectious Diseases
                <http://www.isid.org>

                Date: Thu 27 May 2010
                From: Kelly Lager <Kelly.Lager@ARS.USDA.GOV> [edited]


                I read the 26 May 2010 post about PRRSV being the suspected cause of
                a human death. From what I have read for the 26 May 2010 post [see
                20100526.1751] and a related 3 May 2010 post [20100503.1432,
                published by ProMED-mail's Mekong Basin Disease Surveillance (MBDS)
                web-site], it seems very unlikely the cause of death for the
                individual was a PRRSV infection
                .

                I realize one of the great benefits of ProMED is quickly getting
                information to the public about potential emerging disease issues,
                but the 26 May 2010 report seems to have no supporting data for such
                an unprecedented claim.

                The 3 May 2010 post is a good example of an informative post,
                although it is confusing when people are diagnosed with a _Strep
                suis_ infection and then are considered to be suffering from "blue
                ear," a pig disease believed to be caused by PRRSV, or at least PRRSV
                is presumed to play a significant role in the clinical presentation
                of blue ear.
                In the 26 May 2010 report, there is no mention of a
                possible _Strep suis_ infection in the affected man (a possibility
                based on the 3 May 2010 post), but the etiology of his death is
                considered to be blue ear, and thus PRRSV must be the cause. However,
                there is no diagnostic evidence presented to support this assumption.

                I study pig viruses, and certainly I am sensitive to perceived
                zoonotic issues for the swine industry, so please feel free to view
                my comment as from someone who carries a bias. However, as just
                stated, I see no evidence for what was reported in the 26 May 2010
                post. This is important because many people follow ProMED daily, and
                this post will cause quite a ripple in the swine industry. I
                certainly respect that ProMED is not responsible for economic issues
                concerning the swine industry, but I do feel ProMED has an obligation
                to pass along lay news reports that contain fact. I do understand
                that it is difficult to sometimes sort fact from speculation, so
                please do not take my message too negatively.

                I enjoy following ProMED and believe the world is a better place
                because of ProMED, I just have a concern with the conclusions stated
                in the 26 May 2010 post. If there is anything I can do that can be
                considered constructive to your program, then please let me know.

                --
                Kelly M. Lager, DVM, PhD
                Veterinary Medical Officer
                National Animal Disease Center, USDA-ARS
                Ames, Iowa 50010
                <Kelly.Lager@ARS.USDA.GOV>

                [The published view of a Vietnamese medical official that "a young
                man was suspected to be the 1st to succumb to the deadly pig disease
                PRRS" was posted by ProMED-mail, since it is our job to be an early
                warning system. The commentary in the posting, however, rightly made
                the point that the report must be regarded with caution in the
                absence of confirmatory laboratory diagnosis.

                Having said that, Dr Lager's reservations are consensually shared by
                ProMED-mail's veterinary moderators. As one of us, Mod.PC, remarked
                in an editorial discussion, "pig blood pudding could have contained
                any pathogen such as _Strep suis_, _E. coli_ etc., and there was no
                information that PRRS had been isolated from the dead human
                ;" and
                "there is just no reason to believe that PRRS has suddenly become a
                zoonotic disease. What changed? What is different? Just an evolved
                virus? It is pretty speculative."

                Suspected correlation between PRRS in pigs and human infections with
                _Strep suis_ was widely publicised, since 2005, in China and Viet
                Nam. For an exhaustive discussion of the issue, in July 2007, see
                posting 20070726.2403. And as stated by Mods.QCN/TD in posting
                20100503.1432, referred to by Dr Lager, "an experimental study has
                shown that many more pigs are affected with meningitis when they are
                infected with both _S. suis_ type 2 and PRRS viruses. Therefore,
                there is an assumption that the PRRS virus outbreak may have led to
                an increased risk of transmission of _S. suis_ to humans through
                exposure to pigs with PRRS virus infection and concomitant _S. suis_
                disease
                ." This is certainly so when uncooked pig's blood is consumed,
                as in the current, fatal case.

                Summing up, it seems most unlikely that the case in question was a
                human PRRS infection
                . Obtaining the laboratory results from Viet Nam
                will help to definitely refute the speculation. - Mod.AS]

                Comment


                • #9
                  Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus

                  This is the MBDS post referenced in the above ProMED post. I believe the red text is the confusion cited above.



                  Archive Number 20100503.1432
                  Published Date 03-MAY-2010
                  Subject PRO/MBDS> Streptococcus suis, human - Viet Nam

                  STREPTOCOCCUS SUIS, HUMAN - VIET NAM
                  ***************************************
                  A ProMED-mail post
                  <http://www.promedmail.org>
                  ProMED-mail is a program of the
                  International Society for Infectious Diseases
                  <http://www.isid.org>

                  Date: Thu 29 Apr 2010
                  Source: Sai Gon Giai Phong (SGGP) Daily [edited]
                  <http://www.saigon-gpdaily.com.vn/Health/2010/4/81586/>


                  Four patients have contracted a bacterium called _Streptococcus suis_
                  (_S. suis_) because they have eaten underdone diseased pigs, said a
                  health official on [28 Apr 2010].

                  Dr. Nguyen Van Kinh of the National Institute of Infectious and
                  Tropical Diseases said 4 people suffering from blue ear pig disease
                  come from northern provinces where the disease is spreading at an
                  alarming rate, sending the government scrambling to adopt counter-measures.

                  Of 4 patients, 2 were taken to the hospital in serious condition and
                  had to use a breathing machine, said Dr. Kinh, adding that people
                  usually contract the _Streptococcus suis_ bacterium, a pathogen with
                  serious economic effects on the pig industry worldwide, only when the
                  blue ear disease attacks pigs in the region
                  . The hospital is
                  receiving daily admission of 1-2 people contracting the bacterium. He
                  warned people not to butcher and eat diseased pigs.

                  Infected patients have experienced nausea, fever, vomiting and
                  [hemorrhagic bullae]. Because such symptoms are like normal flu,
                  patients often buy anti-flu drugs to treat themselves at home. They
                  are hence taken to medical facilities late, which sometimes costs
                  them their lives.

                  --
                  Communicated by:
                  PRO/MBDS
                  <promed-mbds@promedmail.org>

                  [_Streptococcus suis_ inhabits pigs and other animals such as
                  ruminants, cats, dogs, deer and horses. _S. suis_ is usually
                  transmitted nasally or orally, and colonizes the palatine tonsils of
                  both clinically ill and healthy pigs. Prevalence of asymptomatic
                  carriage may be as high as 80 percent, and the morbidity ranges from
                  less than one percent to over 50 percent, although it rarely exceeds 5 percent.

                  _S. suis_ infections in humans are reported from countries where pig
                  farming is common. It is likely that exposure to pigs and uncooked or
                  partially cooked pork products are risk factors for _S. suis_
                  infection in humans. The incubation period is as short as 2 hours to
                  as long as a few days. There is no evidence of human to human
                  transmission of _S. suis_.

                  It has been observed that the _S. suis_ infections were reported in
                  regions with blue ear disease (porcine reproductive and respiratory
                  syndrome, PRRS) outbreaks. PRRS is not an animal to human transmitted
                  disease. _S. suis_ infection in pigs can cause septicemia,
                  meningitis, arthritis, and sudden death in young pigs after weaning,
                  but the infection can also be limited to the respiratory tract, where
                  it causes bronchopneumonia. PRRS infection can increase the incidence
                  of _S. suis_ in pigs.

                  An experimental study has shown that many more pigs are affected with
                  meningitis when they are infected with both _S. suis_ type 2 and PRRS
                  viruses. Therefore, there is an assumption that the PRRS virus
                  outbreak may have led to an increased risk of transmission of _S.
                  suis_ to humans through exposure to pigs with PRRS virus infection
                  and concomitant _S. suis_ disease. However, this assumption has not
                  been confirmed.

                  The newswire above reports 4 cases who are infected by _S. suis_ who
                  are under treatment in the National Institute of Infectious Diseases
                  and mentions porcine reproductive and respiratory syndrome (PRRS) as
                  a course of these _S. suis_ cases. It reports that all 4 patients are
                  from provinces where PRRS outbreaks are reported, and all of them ate
                  partially cooked pork before falling sick. The report says 1-2 people
                  with the same symptoms have been admitted to the hospital each day.
                  However, the total number of _S. suis_ cases is not reported.

                  Further information about the total number of _S. suis_ cases and
                  epidemiological information would be highly appreciated.

                  Comment


                  • #10
                    Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus

                    We have been reporting on this event for weeks and we stand by our news analysts:


                    Vietnam- At least 22 cases of swine streptococcus in humans

                    http://www.flutrackers.com/forum/sho...d.php?t=145651

                    Patients infected with streptococcus swine increased-4 dead

                    http://www.flutrackers.com/forum/sho...d.php?t=146983

                    Many suspected cases streptococcus swine in Central Region

                    http://www.flutrackers.com/forum/sho...d.php?t=146980

                    5th strep suisse death in Vietnam

                    http://www.flutrackers.com/forum/sho...d.php?t=147058



                    We do not receive the funding or recognition that ProMed does because we are "common citizens". Well, I like it that way.

                    We are grassroots. Citizens outreach to each other.

                    Comment


                    • #11
                      Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus

                      I believe the red text at the end of this article settles the question. No one suspects PRRS virus in the human; it is the S. suis bacterium that is suspected. Perhaps this article should be sent to ProMED.

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                      Doctors suspect diseased pigs in man?s death
                      Doctors suspect a patient in the central province of Quang Ngai died due to consuming diseased pigs, said a health official on May 24.

                      Dr. Nguyen Xuan Men, deputy director of the Department of Health of the province, confirmed that a 37 year old man in the Quang Ngai City died on May 22. Quang Ngai province is one of the provinces stricken by ?the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)? also known as ?Blue ear" disease in pigs.

                      The victim?s family said he ate pig blood curds on May 21. In the afternoon, he experienced fever, acute diarrhea and bleeding under the skin. He was rushed to Quang Ngai General Hospital for emergency treatment and was then transferred to the Central Hospital in Hue, where he died the next day.

                      The Quang Ngai Department of Health May 24 ordered the Department of Preventive Health to disinfect the patient?s house and the hospital where he was treated, as well as urged the Central Hospital in Hue to announce test results quickly, to confirm if the man in fact died of pig bacterium.

                      Comment


                      • #12
                        Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus

                        An experimental study has shown that many more pigs are affected with
                        meningitis when they are infected with both _S. suis_ type 2 and PRRS
                        viruses. Therefore, there is an assumption that the PRRS virus
                        outbreak may have led to an increased risk of transmission of _S.
                        suis_ to humans through exposure to pigs with PRRS virus infection
                        and concomitant _S. suis_ disease. However, this assumption has not
                        been confirmed.
                        CSI:WORLD http://swineflumagazine.blogspot.com/

                        treyfish2004@yahoo.com

                        Comment


                        • #13
                          Re: Vietnam: Possible human fatal infection with PRRS virus

                          Originally posted by Treyfish View Post
                          6:32 AM, 27/05/2010
                          Quang Ngai: There are no conclusions about the cause of death from suspected swine Streptococcus



                          Afternoon 26 / 5, Dr. Nguyen Xuan Men - Deputy Director of Quang Ngai Department of Health said the Department had written to directors of Hue Central Hospital confirmed causes of death of Mr Bui Van Nhuan (37 years old ) suspected swine streptococcus bacteria in the ward chief Lo, Quang Ngai city.

                          In the last few days, some mass media that Mr. Bui Van Nhuan death by suspected swine Streptococcus. This has to affect the psychology of people and communities.

                          Previous information on, pending the conclusion of the Central Hospital in Hue, Quang Ngai province, the health sector has been assigned to the Center of preventive medicine in promoting active communities on the fields of prevention, such as pigs should not be unknown origin, not given away slaughter and consumption of the pigs died of unknown causes, and recommended people not eat more soup, pig heart or undercooked pork, source unknown Original. /. http://vovnews.vn/Home/Quang-Ngai-Ch...105/144928.vov
                          This post actually calls the man's death "suspected swine Streptococcus", and if I am reading it correctly, it might even say that S. suis is confirmed. I guess we all missed that one.

                          Comment


                          • #14
                            Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus

                            Hat-tip Treyfish. Also see this thread, which contains an article which states that the CFR for S. suis is about 7%, further increasing our confidence that the bacterium is the suspected cause of this fatality.

                            Comment


                            • #15
                              Re: Vietnam: Possible human fatal infection with Porcine Reproductive Respiratory Syndrome (PRRS) virus-reporting error

                              Blue ear pig frightening. Alarms patients swine streptococcus surge
                              05.29.2010, 09:45


                              (24h) - In the last few days, some mass media reported patients N. death due to streptococcus swine, affecting people and the psychological community.
                              In just over a month (late April to May), Hue Central Hospital received 28 patients (BN) in the Central provinces like Quang Ngai, TT-Hue, Quang Tri, Quang Binh ... streptococcus infected pigs in which there are many patients with positive blood cultures and some suspected. Up to date have been 28-5 five patients died due to streptococcus swine and 7 patients were treated at the Faculty of Science-Emergency and spread the Hue Central Hospital.

                              Patients die in Quang Ngai streptococcus swine?

                              The patient died of swine streptococcus latest in Hue Central Hospital as he Bui Van N. (37 years old, resident P. Lo District, Quang Ngai City.) Patients hospitalized in light condition 21-5 high fever, pneumonia and multiple organs failure after eating pig blood pudding, to dawn, the death 22-5.

                              N. In addition patients with 4 patients (including TT-Hue has 2 cases) have died of swine streptococcus. Although the conclusions of BV T. Hue, the patient Ư N. death is due to streptococcus swine, but 26-5 pm, Dr. Nguyen Xuan Men, deputy director of Quang Ngai Department of Health said that the past few days, some mass media reported patients N. death due to streptococcus swine, affecting people and the psychological community.

                              According to BS Passion infect swine streptococcus disease from pigs to humans by contact or eating undercooked pork, pigs eat more soup. The clinical manifestations of this disease is sepsis, bleeding under the skin throughout the body and form for the necrosis, leading to multiple organs failure and death. Previously, on 24-5, Quang Ngai Department of Health has sent an official letter T. BV Hue Ư mention this problem.

                              receiving the written request certifying causes of death of BN N. and BV is an official letter is a formal reply BN N. streptococcus swine die. " According to BS Biology, although BN N. have negative test results because the grassroots level in the previous Patients already taking antibiotics.

                              BS confirmed births, N. patients certainly infected swine streptococcus. Besides based on the results of blood cultures, this result may be determined by epidemiological factors (patients eat pork), clinical signs of disease consistent with symptoms of swine streptococcus, in addition patients also suffered multiple organ meats.

                              Moreover, in many cases the results of blood cultures grew streptococcus swine but not the patient is still infected and some cases being treated in hospital. The medical records of patients N. clearly also have more notes than full haemorrhage, deep black skin, purple lips, the dark eye conjunctivitis, abdominal pain shady forest ...

                              People should not be subjective

                              Although doctors have been advised not to eat pig blood pudding, pig hearts before swine streptococcus status is up, but the observation of PV, quite a subjective and people still did not exclude food "blocks export "outside the menu that morning.

                              According to Dr. Duong Van Sinh, the symptoms of swine streptococcus infections similar to food poisoning such as vomiting, diarrhea loose stools, fatigue, severe shock, multiple organ failure ... However, some cases occur these signs are as food poisoning, so do not come immediately to hospital visits, and a number of cases to hospital too late when it is very difficult to treat.

                              Mr. Hoang Huu Nam, deputy director of TT-Hue Department of Health said: "Afternoon 27-5, the Department has collaborated with the Center for Preventive Medicine and Department of Health profession monitor the situation the positive and suspected cases streptococcus infection in swine BV T. Ư Hue. Of the 5 patients with TT-Hue countryside was being treated at Hue Central Hospital, after taking a specific list on 28-5, the authorities were coordinating Chloramin B injection in the BN area that students live. Of these 5 patients, 3 patients but when the pigs of Animal Health Department inspection, the pigs remain healthy and far, on TT-Hue province has not yet happened blue ear pig. "

                              Situation of swine streptococcus infection increased sharply in the Central, TT-Hue Department of Health to step up propaganda activities. For those cases had positive test results, the Department set up teams to carry out sanitation in areas where patients live.

                              Dr. Duong Van Sinh warns that people should not use processed food from pork of unknown origin, not cooked, when processed to bring gloves, absolutely not eat pig blood pudding. Bacterial transmission from pigs to humans, so when people exposed to pigs should be protected belongings. Immediately after suspected exposure to germs to wash hands thoroughly.

                              Especially when people 40-41 degrees high fever, diarrhea, with patches of hemorrhagic necrosis of the skin, stiff neck ... just need basic medical examination and treatment. The functional need urgently to strengthen quarantine and strict prohibition of circulation of cattle diseases by province. http://us.24h.com.vn/tin-da-nang/bao...98a300213.html
                              CSI:WORLD http://swineflumagazine.blogspot.com/

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