Avian influenza - situation in Egypt - update 58 (WHO, December 15 2011, edited)

[Giuseppe]

[Source: World Health Organization, full page: (LINK). Edited.]

Avian influenza - situation in Egypt - update 58



15 December 2011

The Ministry of Health and Population of Egypt has notified WHO of two cases of human infection with avian influenza A (H5N1) virus.

The two cases are a mother and her young child from Dakahlia Governorate. Both developed symptoms on 26 November 2011.

The mother was admitted to a Hospital on 1 December 2011 and received oseltamivir on admission. The child was hospitalised on 2 December 2011 and received oseltamivir on admission. The mother was 24 weeks pregnant. She died on 3 December 2011. The child is in stable condition.

Investigations into the source of infection indicate that both cases had exposure to sick and dead backyard poultry (chicken and turkeys).

The case was confirmed by the Egyptian Central Public Health Laboratories, a National Influenza Centre of the WHO Global Influenza Surveillance Network, on 3 December 2011.

Of the 155 cases confirmed to date in Egypt, 53 have been fatal.

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[Biological]

Re: Avian influenza - situation in Egypt - update 58 (WHO, December 15 2011, edited)

Just tracing back on confirmed H5N1 ages for 2011 and only 2 cases from Meniat El Nasr, Dakahlia were missing.. Here is the update!

These cases may be revealed somewhere else on Flutrackers!

Case1 or case #154 : 27 (F) pregnant
Case 2 or #155: 1.5 (F)

Information found for cases #154/#155 2011 WHO case list by Sharon Saunders FluTrackers H5N1 - Bird Flu 2011 WHO Confirmed Egypt List of Cases & Links

and refers to posts by FAO EMPRES-i - Global Animal Disease Information
Disease Event ID: 166192
and
Avian influenza - situation in Egypt - update 58
15 December 2011 - The Ministry of Health and Population of Egypt has notified WHO of two cases of human infection with avian influenza A (H5N1) virus.

The two cases are a mother and her young child from Dakahlia Governorate. Both developed symptoms on 26 November 2011.The mother was admitted to a Hospital on 1 December 2011 and received oseltamivir on admission. The child was hospitalised on 2 December 2011 and received oseltamivir on admission. The mother was 24 weeks pregnant. She died on 3 December 2011. The child is in stable condition.

Investigations into the source of infection indicate that both cases had exposure to sick and dead backyard poultry (chicken and turkeys).

The case was confirmed by the Egyptian Central Public Health Laboratories, a National Influenza Centre of the WHO Global Influenza Surveillance Network, on 3 December 2011.

Of the 155 cases confirmed to date in Egypt, 53 have been fatal.
WHO | Avian influenza - situation in Egypt - update 58

http://www.who.int/csr/don/2011_12_15/en/index.html

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WHO case list by Sharon Saunders FluTrackers H5N1 - Bird Flu 2011 WHO Confirmed Egypt List of Cases & Links

2011

#154 - pregnant adult female, onset November 26, hospitalized December 1, died December 3 - Dakahlia governorate Death

#155 - young child of case #154, onset November 26, hospitalized December 2 - Dakahia governorate


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Animal Production and Health Commision for Asia and the Pacific, APHCA (ECTAD-HPAI Situation Update Archive)

ECTAD HPAI Situation Update 15/12/2011 - Issue no. 512
08/12/11 ? Confirmed H5N1 infection in humans, Dakahlia
(FAO Field Officer)
A 27-year old woman and her daughter (one-and-a-half years
old), from Dakahlia Governorate, Meniat Elnasr District; both
developed symptoms on 26 November 2011. The mother was
admitted in the chest hospital on 1 December 2011 and
received Tamiflu. The baby was admitted on 2 December 2011
and also received Tamiflu on admission. Confirmation by RTPCR
at Central Public Health Laboratories (NIC) occurred on 3
December 2011. The mother, who was pregnant (24 weeks),
was in critical condition, with assisted ventilation, and died on
3 December 2011. The baby is still in the hospital in moderate
condition. Investigations into the source of infection indicate
that both cases had exposure to sick and dead backyard poultry (chickens and turkeys). Of the 155 cases confirmed to
date in Egypt, 53 have been fatal.

http://www.aphca.org/Avian%20Infuenza%20Alert/HPAI_update_111215.pdf

Also the 1 yo was reported vaguely by WHO in a wer report "Update on human cases of highly pathogenic avian influenza A(H5N1) virus infection, 2011" in paragragh "Clusters of cases" but sex was missing!

"Clusters are groups of epidemiologically linked human
cases, where transmission may or may not be direct
from human to human. In 2011, 5 clusters comprising
12 cases (1 with onset in 2012) were reported in 3 countries
(Egypt, Cambodia, and 3 in Indonesia). Clusters
make up 17% of all cases (11/62). All but one
cluster involved both adults and young children. The
cluster size was relatively small with 3 clusters of 2 cases
each and 2 of 3 cases each. In the clusters there were
twice as many female cases as male, although when all
cluster cases since 2003 are taken into account the sex
distribution is almost equal.
The median age of cases in clusters was 14.5 years which
is similar to the median age (15 years) for cluster cases
during 2003?2009. Of these cases 83% (10/12) were fatal,
higher than the 64% seen in cluster cases reported during
2003?2009.5 Both surviving cases were 1 year of age;
one was the second case in a cluster of 3 cases in Egypt and the other the second case in a cluster of 2 cases in
Indonesia. When all clusters since 2003 are considered,
the CFR was slightly higher in primary cases (73%) then
for subsequent cluster cases (57%). A blood link was
established among the cases within each of the 5 clusters.
In each cluster, all cases had the possibility of a
common non-human source of exposure and epidemiological
investigations of the clusters do not strongly
suggest human-to human transmission."

http://www.who.int/wer/2012/wer8713.pdf