Tweet
J Med Virol. 2013 Aug;85(8):1420-5. doi: 10.1002/jmv.23622.
Seroprevalence of seasonal and pandemic influenza a in kuala lumpur, malaysia in 2008-2010.
Sam IC, Shaw R, Chan YF, Hooi PS, Hurt AC, Barr IG.
Source
Department of Medical Microbiology, Tropical Infectious Diseases Research and Education Centre, University Malaya, Kuala Lumpur, Malaysia.
Abstract
Relatively little is known about the burden of influenza in tropical countries. The seroprevalence of pandemic influenza A (H1N1) 2009, seasonal H1N1 and H3N2 was determined in Kuala Lumpur, Malaysia. Pre- and post-pandemic residual laboratory sera were tested by hemagglutination-inhibition. The seroprevalence of A(H1N1)pdm09 increased from 3.7% pre-pandemic to 21.9% post-pandemic, giving an overall cumulative incidence of 18.1% (95% CI, 13.8-22.5%), mainly due to increases in those <5, 5-17, and 18-29 years old. In contrast with findings from USA, Europe, and Australia, pre-existing seroprevalence to A(H1N1)pdm09 was low at 5.6% in the elderly age group of >55 years. A(H1N1)pdm09 affected almost a third of those <30 years in Kuala Lumpur. Pre-pandemic seroprevalence was 14.7% for seasonal H1N1 and 21.0% for H3N2, and these rates did not change significantly after the pandemic. Seasonal and pandemic influenza cause a considerable burden in tropical Malaysia, particularly in children and young adults. J. Med. Virol. 85:1420-1425, 2013. ? 2013 Wiley Periodicals, Inc.
Copyright ? 2013 Wiley Periodicals, Inc.
PMID:
23765779
[PubMed - in process]
Seroprevalence of seasonal and pandemic influenza a in kuala lumpur, malaysia in 2008-2010.
Sam IC, Shaw R, Chan YF, Hooi PS, Hurt AC, Barr IG.
Source
Department of Medical Microbiology, Tropical Infectious Diseases Research and Education Centre, University Malaya, Kuala Lumpur, Malaysia.
Abstract
Relatively little is known about the burden of influenza in tropical countries. The seroprevalence of pandemic influenza A (H1N1) 2009, seasonal H1N1 and H3N2 was determined in Kuala Lumpur, Malaysia. Pre- and post-pandemic residual laboratory sera were tested by hemagglutination-inhibition. The seroprevalence of A(H1N1)pdm09 increased from 3.7% pre-pandemic to 21.9% post-pandemic, giving an overall cumulative incidence of 18.1% (95% CI, 13.8-22.5%), mainly due to increases in those <5, 5-17, and 18-29 years old. In contrast with findings from USA, Europe, and Australia, pre-existing seroprevalence to A(H1N1)pdm09 was low at 5.6% in the elderly age group of >55 years. A(H1N1)pdm09 affected almost a third of those <30 years in Kuala Lumpur. Pre-pandemic seroprevalence was 14.7% for seasonal H1N1 and 21.0% for H3N2, and these rates did not change significantly after the pandemic. Seasonal and pandemic influenza cause a considerable burden in tropical Malaysia, particularly in children and young adults. J. Med. Virol. 85:1420-1425, 2013. ? 2013 Wiley Periodicals, Inc.
Copyright ? 2013 Wiley Periodicals, Inc.
PMID:
23765779
[PubMed - in process]
