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  #31  
Old April 22nd, 2008, 11:47 AM
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Newspaper Re: Korea-Suspected Human AI case

About the NINE people serologically tested H5N1 positive:

(...)
South Korea has never reported any human H5N1 cases or deaths, but in September 2006 health officials said five workers who helped cull poultry during outbreaks in 2003 had antibodies to the H5N1 virus but had never had symptoms.

The 2006 report brought the total number of South Korean poultry workers who tested positive for H5N1 antibodies to nine.

Tests on the workers' samples were done at the US Centers for Disease Control and Prevention.
(...)

SOURCE: CIDRAP, http://www.cidrap.umn.edu/cidrap/con...ulling(2).html
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  #32  
Old April 22nd, 2008, 11:57 AM
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Default Re: Korea-Suspected Human AI case

Authorities detect H5 case in Korean soldier

April 23, 2008
A 22-year-old soldier, quarantined since Sunday, is suspected of having been infected with a form of avian influenza virus, but did not develop symptoms, authorities said yesterday.
Tests have shown that the virus detected in the patient¡¯s body was an H5 strain, according to the Korea Center for Disease Control and Prevention. It will take up to three weeks for a lab to confirm whether or not the strain is the deadly H5N1 strain, which has caused massive outbreaks in the Jeolla region since April 1.
The young corporal, identified only by his family name Cho, was sent to help kill infected chickens and ducks on Friday and Saturday. He suffered from high fever and was transported to an army hospital Sunday.
Authorities said his sickness was not related to the bird flu and that his condition has improved.
According to the World Health Organization, only four out of hundreds of strains of avian influenza viruses are known to have caused human infections – H5N1, H7N3, H7N7 and H9N2.
¡°In general, human infection with these viruses has resulted in mild symptoms and very little severe illness, with one notable exception: the highly pathogenic H5N1 virus,¡± according to the WHO. There have been is no confirmed human cases in Korea of H5N1.
¡°Following the initial examination of Cho, a small amount of H5 virus was detected,¡± CDCP head Lee Jong-ku said in a media briefing at the Health Ministry yesterday. ¡°Since his condition is normal now, we believe that the virus did not cause serious harm.¡±
Cho had shown high fever and coughing even before his unit was assigned to the poultry slaughter mission last week, Lee said. He added that bacteria caused the soldier¡¯s illness.
Dr. Park Seung-cheol of Samsung Medical Center, who had examined Cho, said the patient suffered from respiratory complications and high fever.
¡°I concluded that the symptoms were not caused by an avian influenza virus infection, ¡± he said.
The Defense Ministry said all soldiers were withdrawn from the slaughter sites as of 3 p.m. yesterday.
Also yesterday North Korea said it will ban South Korean poultry and eggs from an inter-Korean industrial zone, according to the Unification Ministry.
The North informed the South that the move will take effect Saturday.

http://joongangdaily.joins.com/artic...sp?aid=2888993
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  #33  
Old April 22nd, 2008, 12:05 PM
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Default Re: Korea-Suspected Human AI case

AI first three suspected cases judwi final verification through inspection
Corporal Jo, high fever, respiratory disorders Sunchang jiyeokseo salcheobun jakeopdwi

Edit: 9:18:19 PM 2008-04-22



Gobyeongwonseong avian influenza (AI) occurred in the domestic poultry salcheobun soldier at the scene, which was first put in doubt AI isolates as a treatment for patients in 22 metropolitan jeonbukdo additional cases of human infection was suspected, said.
Countermeasures Headquarters defenses jeonbukdo AI and the AI is balbyeonghan jeongeup Kimje, Sunchang salcheobun beyond the participants and their farm workers, including 7,541 people defenses agents to conduct clinical observations and surveys, but the suspected patients are infected with the human body, said it did not occur .
.
However, the measures defenses Sunchang regional headquarters participating salcheobunjakeope respiratory disorders after being treated in hospital, and army commando brigade Corporal Jo is a member of WHO (World Health Organization) regulations' AI suspected patients' will be included.
WHO headquarters in the regulation defenses measures △ △ AI salcheobunjakeop participate in more than 38 ℃ fever symptoms such as cough △ severe respiratory failure in all the three requirements that the person is' AI suspected patients' states, he added.
있다.
Countermeasures Headquarters defenses salcheobunjakeop participants' gowiheomgun '' probation subjects' 'suspected patients'' hwakjinhwanja 'probation and step bunryuhae management.
Participants in the 7541 people power gowiheomgun Tokyo salcheobun included 206 subjects were observed and drew blood infection still doubt whether the patient did not include me out Corporal Joe unique.
Corporal Joe three weeks whether the AI virus infection through final tests confirm cultivation.
했다.
Defenses of the National Science and Countermeasures Headquarters on July 22, and yongdong Iksan geomyeokwon This material yeosanmyeon each poultry farm in 1 'H5' brother balhime AI virus has been detected on a farm, according to the remaining 61,000 chickens on the farm salcheobunhago lockdown decided.
한편 익산은 도내 최대 양계단지여서 고병원성 AI 발병이 확진될 경우 파장이 클 것으로 우려되고 있다.
Meanwhile, the Tokyo Iksan largest poultry hwakjindoel this case just because the wavelength is large gobyeongwonseong AI outbreaks are feared. http://209.85.135.104/translate_c?hl...6dt%3D20080423
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  #34  
Old April 22nd, 2008, 12:21 PM
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Default Re: Korea-Suspected Human AI case

Quote:
Originally Posted by ironorehopper View Post
About the NINE people serologically tested H5N1 positive:

(...)
South Korea has never reported any human H5N1 cases or deaths, but in September 2006 health officials said five workers who helped cull poultry during outbreaks in 2003 had antibodies to the H5N1 virus but had never had symptoms.

The 2006 report brought the total number of South Korean poultry workers who tested positive for H5N1 antibodies to nine.

Tests on the workers' samples were done at the US Centers for Disease Control and Prevention.
(...)

SOURCE: CIDRAP, http://www.cidrap.umn.edu/cidrap/con...ulling(2).html

A discussion thread on poultry culler infections in South Korea.
http://www.flutrackers.com/forum/sho...34&postcount=1

Subforums on past H5N1 outbreaks in South Korea.
http://www.flutrackers.com/forum/forumdisplay.php?f=370
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  #35  
Old April 22nd, 2008, 12:22 PM
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Opinion Re: Korea-Suspected Human AI case

Quote:
Originally Posted by Treyfish View Post
AI first three suspected cases judwi final verification through inspection
Corporal Jo, high fever, respiratory disorders Sunchang jiyeokseo salcheobun jakeopdwi
In summary, the corporal has:
-- clinical presentation compatible with WHO case definition for H5N1 human infection (...Corporal Jo is a member of WHO (World Health Organization) regulations' AI suspected patients' will be included...; post #33); and
-- preliminary tests results detected H5 genetic material in samples; (...Following the initial examination of Cho, a small amount of H5 virus was detected...; post #32);
-- a bacterial super-infection.

No data about mode of exposure, adherence to PPE wearing, and no details on treatments and current health status. Also, the soldier chemoprophylaxis status not mentioned at this point. No data about seasonal human vaccination.
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  #36  
Old April 22nd, 2008, 12:31 PM
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Default Re: Korea-Suspected Human AI case

Quote:
Originally Posted by ironorehopper View Post
In summary, the corporal has:
-- clinical presentation compatible with WHO case definition for H5N1 human infection (...Corporal Jo is a member of WHO (World Health Organization) regulations' AI suspected patients' will be included...; post #33); and
-- preliminary tests results detected H5 genetic material in samples; (...Following the initial examination of Cho, a small amount of H5 virus was detected...; post #32);
-- a bacterial super-infection.

No data about mode of exposure, adherence to PPE wearing, and no details on treatments and current health status. Also, the soldier chemoprophylaxis status not mentioned at this point. No data about seasonal human vaccination.
I think the H5 genetic material description is just like the H5 description for the poultry. There have been no reports of H5 other than HPAI H5 or H5N! and the soldier was culling, so there is little doubt that this is an H5N1 infection (although it may be a mild infection similar to infections in Egypt last year).

I suspect the mild H5N1 infections are MUCH more widespread than reported (including India and Bangladesh).
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  #37  
Old April 22nd, 2008, 12:32 PM
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Default Re: Korea-Suspected Human AI case

Hi ironorehopper

Hospitals and medical staff have also been taking treatment Tamiflu, in case of any incident. ( post one from treyfish )

So I think the soldier is taking tamiflu, and I read in a post from dutchy that he is taking antibiotics
( The release said the soldier¡¯s condition improved after he received antibiotics and that everyone who had contact with him were also given medicine and will be monitored for 10 days )

it could be an avian flu ( because 2 tests > 0 ) AND a bacterial pneumonia.
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  #38  
Old April 22nd, 2008, 12:33 PM
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Opinion Re: Korea-Suspected Human AI case

Quote:
Originally Posted by Laidback Al View Post
A discussion thread on poultry culler infections in South Korea.
http://www.flutrackers.com/forum/sho...34&postcount=1

Subforums on past H5N1 outbreaks in South Korea.
http://www.flutrackers.com/forum/forumdisplay.php?f=370

You may agree that '60 per cent CFR' is a MEAN value, and it has a relative value. Variables to keep into account: - cases from geographical distinct areas; - infections due to different H5N1 lineages with distinct antigenic and genetic features; - cases detected for several years. Data is not part of an uniform set and should be careful evaluated.
It is also to be noted that recently Pakistani patients were confirmed positive by serology in presence of atypical H5N1 clinical presentation.
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  #39  
Old April 22nd, 2008, 12:43 PM
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Default Re: Korea-Suspected Human AI case

4-22-08

Disease Management Division 22 suspected symptoms of avian influenza (AI) in the first round of a survey conducted by soldiers, AI type H5 virus has been detected.

However, the AI virus, the disease control division of the soldiers exposed to the virus but without byeongeneun taken out of the walls, and estimated that the possibility (bulhyeonseong infection).

Center for Disease Control Advisory Committee Advisory Committee Chairman bakseungcheol (Samsung Medical Center professor), "AI virus was detected in primary screening results," "AI, but the patient is infected with a bacterial infection in addition to the possibility there would be progress in mind," he said. In this case, the virus is still in the body, came to us out of the walls.

Disease management is the primary screening test headquarters separated from the patient gageommul antigen gene amplification (PCR) tests have been positive results, he said. Gabriel gobyeongwonseongin type H5 virus was found.

Advisory Committee Chairman night, "AI infection, such as fever and cough symptoms are excessive bacterial infection symptoms," "shallow, or bacterial pyeryeomil, AI virus, a bacterial infection, but in a separate proceeding would likely be separate report," he said. Patients will be put in operation before salcheobun showed symptoms of the flu jeomeseoda.

Chairman of the advisory night, "This is not a result of cell culture hwakjin through the PCR results confirm once again," "The World Health Organization (WHO) is currently a patient's AI bunryusang classified as suspected patients, but ultimately it is not confirmed." .

WHO has finalized the patient in three stages according to AI. AI was first exposed to the virus, symptoms of fever and pneumonia patients classified as suspicious, and if you see AI, since genetic tests (PCR) amplification, and the best AI AI virus positive patients classified as presumed. AI virus is a virus or antibodies final separation from the antibody tests, the increase is more than four times the hwakjinhwanja AI. Disease management is finalized headquarters was expected to take up to 1-3 weeks....

Meanwhile, disease management division, which was put to the task salcheobun 250 people, a medical condition such as a special observation, said medical staff.........

http://news.moneytoday.co.kr/view/mt...35&type=2&NVEC

credits Pugmom
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  #40  
Old April 22nd, 2008, 12:51 PM
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Post Re: Korea-Suspected Human AI case

Quote:
Originally Posted by niman View Post
I think the H5 genetic material description is just like the H5 description for the poultry. There have been no reports of H5 other than HPAI H5 or H5N! and the soldier was culling, so there is little doubt that this is an H5N1 infection (although it may be a mild infection similar to infections in Egypt last year).

I suspect the mild H5N1 infections are MUCH more widespread than reported (including India and Bangladesh).
In fact. I've done a list for the soldier almost certain final H5N1 diagnosis. He meets WHO clinical features, laboratory results (although officially stated as preliminary).
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  #41  
Old April 22nd, 2008, 12:54 PM
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Default Re: Korea-Suspected Human AI case

Commentary

http://www.recombinomics.com/News/04...orea_Mild.html
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  #42  
Old April 22nd, 2008, 12:56 PM
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Post Re: Korea-Suspected Human AI case

Quote:
Originally Posted by Anne View Post
Hi ironorehopper

Hospitals and medical staff have also been taking treatment Tamiflu, in case of any incident. ( post one from treyfish )

So I think the soldier is taking tamiflu, and I read in a post from dutchy that he is taking antibiotics
( The release said the soldier¡¯s condition improved after he received antibiotics and that everyone who had contact with him were also given medicine and will be monitored for 10 days )

it could be an avian flu ( because 2 tests > 0 ) AND a bacterial pneumonia.
Well. He meets clinical and laboratory results for a confirmed human case of H5N1. In addition, chemoprophylaxis and prompt hospital admission may result in a more favorable outcome.
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  #43  
Old April 22nd, 2008, 12:58 PM
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Default Re: Korea-Suspected Human AI case

Tuesday, April 22, 2008 14:15:16
A Korean soldier has tested positive for a highly pathogenic strain of avian influenza.

The 22-year-old man, identified only by his surname Cho, is suspected of having contracted the virus at a farm in Sunchang, North Jeolla Province. He had taken part in culling operations there to dispose of poultry likely to have been infected with the bird flu.

The Korea Centers for Disease Control and Prevention (KCDCP) said the H-Five-type virus, which causes the bird flu, was found in the soldier's blood sample.

The KCDCP said the H-Five-type virus is not usually found in humans, raising the possibility that the soldier may have been infected.

Authorities said a second test is under way, but it will take one to three weeks for the results.

They said Cho had a mild cold before participating in the culling operations. They did not rule out the possibility of viral pneumonia. http://english.kbs.co.kr/news/newsvi...key=2008042213
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  #44  
Old April 22nd, 2008, 01:01 PM
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Default Re: Korea-Suspected Human AI case

I don't find the non translate worlds with this translator :http://www.zkorean.com/dictionary.ph...=hwakjinhwanja


hwakjin and hwakjinhwanja
: could be " virus " or viral , because :

This is not a result of cell culture hwakjin through the PCR results confirm once again
the increase is more than four times the hwakjinhwanja AI.
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  #45  
Old April 22nd, 2008, 01:18 PM
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Default Re: Korea-Suspected Human AI case

Quote:
Originally Posted by Anne View Post
I don't find the non translate worlds with this translator :http://www.zkorean.com/dictionary.ph...=hwakjinhwanja


hwakjin and hwakjinhwanja : could be " virus " or viral , because :

This is not a result of cell culture hwakjin through the PCR results confirm once again
the increase is more than four times the hwakjinhwanja AI.
4X refers to antibody titer (definition of WHO confirmed case).
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  #46  
Old April 22nd, 2008, 01:59 PM
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Default Re: Korea-Suspected Human AI case

Link to the english version of the Ministry for Health, Welfare and Family Affairs. No current or timely news releases on the human H5N1.

http://english.mohw.go.kr/
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  #47  
Old April 22nd, 2008, 02:01 PM
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Default Re: Korea-Suspected Human AI case

Commentary

Soldier With Mild Confirmed H5N1 Raises Pandemic Concerns

Recombinomics Commentary 15:08
April 22, 2008

Tests have shown that the virus detected in the patient's body was an H5 strain, according to the Korea Center for Disease Control and Prevention. It will take up to three weeks for a lab to confirm whether or not the strain is the deadly H5N1 strain, which has caused massive outbreaks in the Jeolla region since April 1.

The young corporal, identified only by his family name Cho, was sent to help kill infected chickens and ducks on Friday and Saturday. He suffered from high fever and was transported to an army hospital Sunday.

Authorities said his sickness was not related to the bird flu and that his condition has improved.


The above comments provide more detail on the H5N1 infected soldier in South Korea. The “H5” designation for the soldier is similar to comments on the H5 infected birds in South Korea. There is no data supporting anything other than H5N1 for the outbreaks in South Korea. In the OIE report, some were H5N1 confirmed while others were HPAI H5 confirmed at the time of filing. No H5 had been confirmed to be low path H5.

The rapid recovery could have been due to both antibiotic and Tamiflu treatment, if the patient had secondary bacterial pneumonia. However, the bacterial infection does not invalidate the H5 detection.

More detail on how the soldier was infected would be useful. Pictures of culling operations showed cullers in PPE’s from head to toe. Moreover, cullers are usually on prophylactic Tamiflu (oseltamivir).

The denial of the associated of bird flu symptoms with H5N1 infections raise concerns of additional H5N1 patients that are not considered H5N1 infections because of arbitrary and capricious definitions. The infected culler also raises concerns about infected farmers who have not used PPE’s or Tamiflu.

The H5 positive result raises concerns of widespread mild H5N1 patients in South Korea as well as Bangladesh and India. The passage of H5N1 through human hosts increases the likelihood of human adaptation and efficient transmission.

More information on the patient, PPE’s and prophylaxis would be useful.

http://www.recombinomics.com/News/04...orea_Mild.html
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  #48  
Old April 22nd, 2008, 02:58 PM
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Commentary

http://www.recombinomics.com/News/04...nsparency.html
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  #49  
Old April 22nd, 2008, 05:36 PM
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Soldier May Be Korea's 1st Human Bird Flu Case
Health authorities in Korea are on high alert in the wake of what could be the country's first human case of bird flu. A soldier who had been involved in the culling process of infected poultry is showing symptoms of the deadly disease.
Reportedly suffering from a high fever after destroying avian influenza affected poultry last week, a Korean soldier has been hospitalized in a quarantine ward. The soldier, whose family name is Cho, allegedly had body temperatures of up to 39.8 degrees Celsius, and was in and out of a coma. The high fever dissipated after he was treated with antibiotic and anti-viral drugs.
The Korea Center for Disease Control and Prevention says while Cho's symptoms are those of avian influenza, it's also possible that he might be affected with bacterial pneumonia.
The center added that it would take up to three weeks for them to see what the soldier is suffering from. The center will dose everyone who had contact with Cho in the last couple of days with antiviral drugs and closely monitor them for the next 10 days. In related news, government officials are discussing ways to prevent the spread of avian influenza to humans. They agreed to speed up the reporting system as immediate quarantine of patients is considered the first priority. Officials also agreed to expand the procurement of Tamiflu, an antiviral drug used for treating AI. At present, the amount available can treat 1.2 million people, only 2 percent of Korea's total population. Arirang News

http://english.chosun.com/w21data/ht...804230005.html
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  #50  
Old April 22nd, 2008, 06:07 PM
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Default Re: Korea-Suspected Human AI case

Quote:
Originally Posted by ironorehopper View Post
You may agree that '60 per cent CFR' is a MEAN value, and it has a relative value. Variables to keep into account: - cases from geographical distinct areas; - infections due to different H5N1 lineages with distinct antigenic and genetic features; - cases detected for several years. Data is not part of an uniform set and should be careful evaluated.
It is also to be noted that recently Pakistani patients were confirmed positive by serology in presence of atypical H5N1 clinical presentation.
In Egypt in the spring of 2007, only one in 17 confirmed H5N1 cases was fatal, and most who were infected did NOT develop pneumonia (but were positive by PCR, virus isolation, and virus sequence).
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  #51  
Old April 22nd, 2008, 07:27 PM
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Default Re: Korea-Suspected Human AI case

Source: http://www.stripes.com/article.asp?s...&article=54267

South Korean soldier may have contracted bird flu
By Ashley Rowland and Hwang Hae-rym, Stars and Stripes
Pacific edition, Thursday, April 24, 2008



SEOUL — A 22-year-old South Korean soldier who helped kill chickens infected with avian flu remained in stable condition Tuesday afternoon, two days after he reported having possible symptoms of the deadly virus.

The Special Forces corporal, identified only by his last name, Cho, is being quarantined and treated with antibiotics in a South Korean military hospital in Bundang, a suburb of Seoul, according to a spokesman for South Korea’s Ministry of National Defense.

If testing shows he has the disease, he will be the first in South Korea.

“It’s a big deal,” said Lt. Col. Eric Lund, a preventive medicine consultant for 18th Medical Command. “All of Korea is waiting to see, did this happen or not.”

Officials won’t know for one to three weeks if Cho has bird flu because his symptoms could be caused by bacterial pneumonia, according to a statement from the Ministry for Health, Welfare and Family Affairs.

Cho complained of a fever and breathing problems on Sunday, after helping cull H5N1-infected birds on Friday and Saturday. The spokesman said his condition is improving and his fever is gone.

South Korea raised its avian flu alert to orange last week, the second-highest level in its four-tier alert system, after outbreaks spread to poultry farms across the country. Officials have destroyed more than 3.7 million poultry and 30 million eggs during this outbreak, Lund said.

Nearly 2,000 other South Korean soldiers have culled chickens and ducks since April 17. Those soldiers are being monitored every morning and evening for signs of H5N1, and are taking a 10-day course of Tamiflu, a flu treatment drug, the MND spokesman said.

The soldiers were given human influenza vaccinations before the culling, as well as protective uniforms, gloves and masks, which were destroyed after use.

South Korea has not asked the U.S. military for help with the culling and isn’t expected to make a request, 8th Army spokesman Lt. Col. B.J. Bailey said.

Lund said humans rarely catch the avian flu virus from birds, unless they work closely with them at farms or slaughterhouses. Humans rarely transmit it to each other, though experts expect that to change.

“We all think it’s a matter of when, not a matter of if, this bug gets wings and is able to be transmitted from human to human,” Lund said. “That’s the pandemic that everyone’s preparing for.”

Migrating water fowl typically spread the disease to domestic chickens, ducks and other fowl. Birds carry the virus in their saliva and feces, spread it easily to each other and die rapidly, usually within 48 hours of contracting the disease.

Ninety to 100 percent of birds infected with the highly pathogenic strain of H5N1 die from it, Lund said. Sixty percent of humans who catch avian flu die from it, he said.

Of the 381 confirmed human cases of bird flu, 240 have died. Most of those cases were in Indonesia, China, Egypt, Vietnam and Thailand.

Bird flu symptoms

* Fever
* Cough
* Sore throat
* Muscle aches
* Eye infections
* Trouble breathing or expanding lungs
* Pneumonia

Visit a doctor if you show these symptoms and have been around dead or live birds, or someone with avian flu, said Lt. Col. Eric Lund, preventive medicine consultant with 18th Medical Command in Seoul, South Korea. Humans who contract avian flu are hospitalized and isolated from other patients, and treated with antimicrobials.
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  #52  
Old April 22nd, 2008, 07:50 PM
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Default Re: Korea-Suspected Human AI case

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Commentary

Mild H5N1 In Korea Raises Transparency Issues

Recombinomics Commentary 19:42
April 22, 2008

The confirmation of mild H5N1 in a soldier in South Korea raises serious transparency issues. The concerns in South Korea were increased as government agencies issued statements splitting hairs between H5N1 confirmed and HPAI H5 confirmed poultry outbreaks. HPAI H5 is confirmed with a sequence of the HA cleavage site, which for all practical purposes confirms H5N1. The sequences of the HPAI H5 and H5N1 would be virtually identical removing virtually all doubt that the H5 positive cases are H5N1 positive cases.

Now the government is using the same hair splitting approach to delay confirming that the soldier is H5N1 positive with the same H5N1 detected in the birds being culled. The number of infected farms is approximately 50, indicating the H5N1 is easily passed from farm to farm, and these connections are likely linked to migratory birds (see satellite map). The infection of a soldier/culler, who had PPE’s and prophylactic Tamiflu would once again suggest that transmission to humans was efficient. The status of the other hospitalized patients is unclear, but if they are on Tamiflu, the likelihood that they will test negative is high, because Tamiflu lowers viral load to an undetectable level. Moreover, government comments that bird flu symptoms in an H5N1 infected patient are not due to the H5N1 raises serious credibility issues.

Unfortunately, such issues are not limited to South Korea. Japan has announced the implementation of a pre-pandemic vaccine program, even though they have not reported H5N1 since early 2004. The similarity between the H5N1 in South Korea in 2003/2004 and Japan in 2004 strongly suggests that there was H5N1 in Japan in 2006/2007 and 2007/2008, when South Korea reported large poultry outbreaks. Closely related H5N1 was also found in fecal samples from site frequented by migratory bird, which migrate from H5N1 confirmed areas in Mongolia. Thus, the lack of any H5N1 reports in Japan for this season or last season remains suspect.

The level of suspicion is even higher for India, which has reported its largest outbreak to date in West Bengal and Tripura. In both countries, the initial denials of H5N1 infections and suggestions that the dead birds had died from Newcastle Disease was not credible since the dead birds had been vaccinated against Newcastle Disease and dogs, cats, and jackals died after eating the infected birds. In the outbreaks in West Bengal the deaths of resident and migratory birds in proximity to the H5N1 poultry was noted. However, India has never reported an H5N1 case in anything other than poultry, even though migratory birds that winter in India spend the spring and summer in H5N1 positive nature reserves in China and Mongolia.

Moreover, films of dead birds and villagers in West Bengal left little doubt that there were human H5N1 infections. The villagers had no PPE’s and many had eaten the H5N1 positive birds. When these villagers developed symptoms, they were not tested for H5N1, raising concerns of significant levels of mild infections.

The same situation exists in Bangladesh. Migratory birds also fly into Bangladesh because of the Ganges Delta, which is shared with India. Although Bangladesh has confirmed H5N1 in wild birds falling from trees and populating metropolitan areas, Bangladesh has never reported H5N1 in a migratory bird or human. These detection / reporting issues also raise concerns about Bangladesh.

Similarly, Pakistan has acknowledged human to human transmission of H5N1, but reports were withheld for six weeks and released only after two brothers had died and two other brothers had developed pneumonia over an extended time frame. Initially, only one positive was confirmed by WHO because of sample degradation.

Sequences from earlier outbreaks in South Korea, India, Pakistan, and Afghanistan are all clade 2.2.3. The human cases in Pakistan and South Korea suggest all of these countries have had human cases, although only Pakistan has reported a WHO confirmed case.

The H5N1 outbreaks in the above countries have almost certainly caused human infections that have not been reported or confirmed. Many of these cases may have been mild, which increases the likelihood of transmission to humans and the associated adaptation to humans.

Thus, H5N1 is clearly evolving below the radar in these countries and there is little reason to believe that such mild cases are not widespread as was seen last season in Egypt.


.
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Old April 22nd, 2008, 09:57 PM
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Soldier May Be Korea's 1st Human Bird Flu Case
Health authorities in Korea are on high alert in the wake of what could be the country's first human case of bird flu. A soldier who had been involved in the culling process of infected poultry is showing symptoms of the deadly disease.
Reportedly suffering from a high fever after destroying avian influenza affected poultry last week, a Korean soldier has been hospitalized in a quarantine ward. The soldier, whose family name is Cho, allegedly had body temperatures of up to 39.8 degrees Celsius, and was in and out of a coma. The high fever dissipated after he was treated with antibiotic and anti-viral drugs.
The Korea Center for Disease Control and Prevention says while Cho's symptoms are those of avian influenza, it's also possible that he might be affected with bacterial pneumonia.
The center added that it would take up to three weeks for them to see what the soldier is suffering from. The center will dose everyone who had contact with Cho in the last couple of days with antiviral drugs and closely monitor them for the next 10 days. In related news, government officials are discussing ways to prevent the spread of avian influenza to humans. They agreed to speed up the reporting system as immediate quarantine of patients is considered the first priority. Officials also agreed to expand the procurement of Tamiflu, an antiviral drug used for treating AI. At present, the amount available can treat 1.2 million people, only 2 percent of Korea's total population. Arirang News

http://english.chosun.com/w21data/ht...804230005.html
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Old April 22nd, 2008, 10:16 PM
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Still current at: 23 April 2008
Updated: 22 April 2008

This advice has been reviewed and reissued with an amendment to the Health (Avian Influenza) section (outbreaks in April 2008 in North Jolla, South Jolla and Gyenonggi Provinces) . The overall level of the advice has not changed.



Avian Influenza (Bird Flu)

There have been outbreaks of Avian Influenza (Bird Flu) in domestic poultry in South Korea. Since the most recent outbreak of Avian Influenza was reported on 1 April 2008, 23 cases of the H5N1 virus and 18 cases of non-H5N1 strains of Avian Influenza have been confirmed in North and South Jolla provinces (approximately 260km south-west of Seoul). On 16 April 2008 a suspected outbreak in Gyenonggi Province (60km from Seoul) was confirmed as H5N1. The Korean authorities have established a poultry quarantine zone and movement controls in order to prevent the spread of the virus. The Korean authorities are on the alert for any further outbreaks. No human infections or deaths have been reported.

The risk to humans from Avian Influenza is believed to be very low. As a precaution you should avoid visiting live animal markets, poultry farms and other places where you may come into close contact with domestic, caged or wild birds; and ensure poultry and egg dishes are thoroughly cooked.

The World Health Organisation (WHO) has warned of the possibility that the Avian Influenza outbreaks could lead at some point to a human flu pandemic, if a virus mutates to a form which is easily transmissible between people.

For more information please visit: Avian Influenza Factsheet http://www.fco.gov.uk/en/travelling-...ta=health&pg=5
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Old April 22nd, 2008, 10:21 PM
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Old April 23rd, 2008, 03:03 AM
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AI no doubt in Tokyo patients' peace of mind '
道, 살처분 참여자 일일이 조사
道, every survey participant salcheobun
[경기일보 2008-4-23]
[2008-4-23 game Ilbo]
gobyeongwonseong salcheobun poultry avian influenza (AI) occurred at the scene of the injected area soldier AI isolates uisimdwae treatment for the infection of target beneficiaries Gyeonggi gowiheomgun survey results did little to the present cases of suspected human infections have been relieved hwakindwae The sigh.
AI Gyeonggi Province on October 22, the health authorities are beyond the farm workers and Pyeongtaek balbyeonghan salcheobun participants, including 763 men defenses agents to conduct clinical observations and surveys, and more suspected patients infected with the human body to the present day, but did not identify the cause.
Health authorities are also salcheobun participants who administer immunizations and hangbayireoseuje, personal protective gear, such as payment for a precautionary measure to implement the AI virus is frequently exposed to a lot of farm workers, including 308 blood tests were gowiheomgun regularly, and set the state.
So far, more than 38 are in the middle of looking at the same time symptoms of fever and cough 'suspected patients' blood tests are no more than symptoms appeared deungeseodo case is not explained.
But turning 30 gowiheomgun subjects of the phone lines were down due to the ongoing management mihwakindoen alert, as the tension in his state director.
Also said, "AI virus in the body associated with the disease invading 'hwakjin patients' disease do not know you are never reported, as expected, systematic inspections. Nagalgeot continuously," he explained.

http://209.85.135.104/translate_c?hl...%26year%3D2008
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Old April 23rd, 2008, 03:30 AM
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H5N1 Media Spin In Korea Raises Pandemic Concerns

Recombinomics Commentary 03:17
April 23, 2008

The soldier, whose family name is Cho, allegedly had body temperatures of up to 39.8 degrees Celsius, and was in and out of a coma. The high fever dissipated after he was treated with antibiotic and anti-viral drugs.

The Korea Center for Disease Control and Prevention says while Cho's symptoms are those of avian influenza, it's also possible that he might be affected with bacterial pneumonia.

The above comments by the Korea Center for Disease Control and Prevention raise serious credibility issues, since the patient has already tested positive for H5 by PCR and the test were done by the Korea Center for Disease Control and Prevention. Since the soldier developed symptoms after culling H5N1 positive chickens and ducks, a bacterial infection is of little consequence.

The patient and hospital contacts have been treated with Tamiflu, and the issue of bacterial pneumonia just serves to confuse.

This confusion is similar to earlier reports which tried to make distinctions between confirmed H5N1 and confirmed HPAI H5. The HPAI H5 will be H5N1 when the testing is completed because the sequence of the H5 is the same as the sequence of the H5N1.

These efforts to confuse raise serious credibility issues. Since the patient appears to have responded quickly to treatment, the case will likely be relatively mild. Therefore, detection of additional cases may be influenced by Tamiflu treatment. Such data can be easily affected by agencies that put out confusing statements and press releases.

These confusing statements remain a cause for concern.
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Old April 23rd, 2008, 03:35 AM
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AI suspicious blood tests soldiers' normal '… 24 days isolation Releases


Avian Influenza (AI) infection has uisimdwae soldiers for the special isolation room gyeokridwae measures are expected to be released on the 24th.

Disease management division has been given to the soldiers eumap treated in the isolation of his room suchideung blood test results are normal white blood cell recovery, as the 24th at 8 pm plans to release the quarantine measures yesterday.


다.
Show me the World Health (WHO) recommendations on the rules of antiviral drug treatment bokyonghan 5 days after symptoms disappear in a special isolation facility can be disabled. AI in the last 20 suspected soldiers received treatment for two days beginning almost disappeared from the symptoms of the disease control division.

Center for Disease Control said, "The primary care physician and the patient's condition, but as a result of the advisory committee meeting today, it is possible to turn off the quarantine, but the WHO criteria for judging follow quarantine for 24 days to release the plan," he said.

After isolation eumap disabled return to normal daily life omgilji room will be determined later.

This is a private operation salcheobun injected AI symptoms such as high fever after treatment have been received to show the isolation of virus-type H5 gene was detected in body fluids as possible answer gobyeongwonseong H5N1 infection.

Healing and the results of various tests, but when the soldiers mirwobol exposed to the AI virus, the disease did not occur, but the so-called `bulhyeonseong infection (不显性感染) 'estimated potential.
(서울=연합뉴스)

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Old April 23rd, 2008, 07:25 AM
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Old April 23rd, 2008, 04:20 PM
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Default Re: Korea-Suspected Human AI case

AI infection symptoms suspected belligerent soldier

Quarantine measures blood tests normal recovery plan Releases

작성 : 2008-04-23


Sunchang involved in a regional task salcheobun respiratory failure due to avian influenza (AI) infection in the hospital uisimdwae army corporal quarantine treatment for Moe Joe for 24 days quarantine measures are lifted.
Disease management headquarters 23 days "have been treated in hospital rooms to isolate eumap Corporal Joe's been given a blood test results are normal white blood cell levels and to recover 8:00 p.m. on the 24th to release plans to quarantine measures," he said.
해제할 수 있다.
Show me the World Health (WHO) recommendations, according to the rules of antiviral drug treatment bokyonghan five days after symptoms disappear, can be turned off in a special isolation facility.
Corporal Joe received treatment in the past two days, starting July 20 is almost disappeared from the symptoms of the disease control headquarters said.
But isolation is disabled eumap after the return to normal daily life depends omgilji room will be determined later.
Sunchang last 18 to 19 chickens from ducks for the AI to take action salcheobun Corporal Joe has been put into operation after troops back from 20th after the fever and showed symptoms of respiratory disorders such as AI isolates from the treatment received fluids' H5 ' Will the virus genes are detected as gobyeongwonseong 'H5N1' had raised the possibility of infection. http://66.102.9.104/translate_c?hl=e...6dt%3D20080424
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