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2009 pandemic influenza A (H1N1) virus infection in postpartum women in California

tetano

Editor, Senior Moderator
AJOG

2009 pandemic influenza A (H1N1) virus infection in postpartum women in California

* Janice K. Louie, MD, MPH
Affiliations
o California Department of Public Health, Richmond, CA
o Corresponding Author InformationReprints: Janice K. Louie, MD, California Department of Public Health, 850 Marina Bay Pkwy., Richmond, CA 94804
email address
* , Denise J. Jamieson, MD, MPH
Affiliations
o the National Center for Chronic Disease Prevention and Health Promotion
* , Sonja A. Rasmussen, MD, MS
Affiliations
o the National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA

Received 7 June 2010; received in revised form 8 July 2010; accepted 27 August 2010. published online 12 November 2010.



Objective:

The objective of the study was to characterize severe illness because of the 2009 pandemic influenza A (H1N1) infection in postpartum women.
Study Design:

We reviewed case reports of infected hospitalized postpartum (≤6 months from delivery) women identified through statewide surveillance in California. From April 23 through August 11, 2009, all hospitalizations and/or deaths were reported. After August 11, reporting was limited to cases requiring intensive care or deaths.
Results:

From April 23 to December 31, 2009, 15 cases were reported; 11 (73%) had symptom onset within 7 days postpartum. Of 10 hospitalized cases reported through August 11, 4 required intensive care, 3 required mechanical ventilation, and 2 died. Of 5 cases requiring intensive care reported after August 11, all required mechanical ventilation and 1 died. Overall, 6 (43%) received antivirals within 48 hours of symptom onset.
Conclusion:

The 2009 H1N1 can cause severe illness in postpartum women, especially in the first week following delivery.

http://www.ajog.org/article/S0002-9378(10)01112-9/abstract
 
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