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A new macrolide from a marine-derived fungus Aspergillus sp

tetano

Editor, Senior Moderator
Nat Prod Commun. 2013 Aug;8(8):1127-8.
A new macrolide from a marine-derived fungus Aspergillus sp.
Bao J, Xu XY, Zhang XY, Qi SH.
Source

Key Laboratory of Marine Bio-resources Sustainable Utilization/RNAM Center for Marine Microbiology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, PR China.
Abstract

A new 16-membered macrolide named aspergillide D (1), along with six known compounds, including two polyketones (2-3) and four alkaloids (4-7), were isolated from the culture broth of a marine-derived fungus Aspergillus sp. SCSGAF 0076. The structure of 1 was elucidated on the basis of NMR and mass spectra. Compound 5 showed an obvious inhibitory effect on influenza virus strains H1N1 and H3N2.

PMID:
24079185
[PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/24079185
 
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