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AIDS . Humoral response 24 months after the first COVID-19 vaccination in people with HIV with and without diabetes

tetano

Editor, Senior Moderator
AIDS


. 2024 Dec 1;38(15):2100-2103.
doi: 10.1097/QAD.0000000000004026. Epub 2024 Nov 14. Humoral response 24 months after the first COVID-19 vaccination in people with HIV with and without diabetes

Louise Bering[SUP] 1 [/SUP], Line Dam Heftdal[SUP] 1 2 [/SUP], Safura-Luise Heidari[SUP] 1 [/SUP], Sebastian Rask Hamm[SUP] 1 [/SUP], Cecillie Bo Hansen[SUP] 3 [/SUP], Dina Leth Møller[SUP] 1 [/SUP], Mia Pries-Heje[SUP] 4 [/SUP], Kamille Fogh[SUP] 5 [/SUP], Rasmus Bo Hasselbalch[SUP] 5 [/SUP], Laura Pérez-Alós[SUP] 3 [/SUP], Jan Gerstoft[SUP] 1 6 [/SUP], Thomas Benfield[SUP] 6 7 [/SUP], Selina Kikkenborg Berg[SUP] 4 6 [/SUP], Anne Vinggaard Christensen[SUP] 4 [/SUP], Nina Marie Birk[SUP] 4 [/SUP], Linda Maria Hilsted[SUP] 8 [/SUP], Sisse Rye Ostrowski[SUP] 3 6 [/SUP], Ruth Frikke-Schmidt[SUP] 6 8 [/SUP], Erik Sørensen[SUP] 3 [/SUP], Kirsten Grønbæk[SUP] 2 6 9 [/SUP], Henning Bundgaard[SUP] 4 6 [/SUP], Kasper Iversen[SUP] 5 6 10 [/SUP], Peter Garred[SUP] 3 6 [/SUP], Susanne Dam Nielsen[SUP] 1 6 11 [/SUP]



Affiliations
Abstract

People with HIV (PWH) and people with diabetes mellitus have increased risk of severe COVID-19, but little is known about humoral response to COVID-19 vaccines in PWH with DM. We investigated SARS-CoV-2 antireceptor-binding domain (anti-RBD) immunoglobulin G (IgG) geometrical concentrations and neutralizing antibody capacity (nAB) in PWH with and without diabetes mellitus. Anti-RBD IgG and nAB in COVID-19-vaccinated PWH were not associated with diabetes mellitus-status or HbA1c 24 months after the initial COVID-19 vaccination.


 
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