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Am J Med Case Rep . Syncope Associated with Sinus Nodal Dysfunction in a COVID-19 Patient: A Case Report and Review of the Literature

tetano

Editor, Senior Moderator
Andrew V Doodnauth[SUP] 1 [/SUP], Ahmad Jallad[SUP] 2 [/SUP], Dahlia Rizk[SUP] 3 [/SUP], Emmanuel Valery[SUP] 1 [/SUP], Samy I McFarlane[SUP] 1 [/SUP]



Affiliations

Abstract

COVID-19 caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is associated with significant cardiovascular dysfunction in patients with, and without, pre-existing cardiovascular disease [1]. There are now well-documented cardiac complications of COVID-19 infection which include myocarditis, heart failure, and acute coronary syndrome [2]. There is growing evidence showing that arrhythmias are also one of the major complications of COVID-19. We report a patient with no known cardiac conduction disease who presented with syncope, positive SARS-CoV-2 PCR, who was persistently bradycardic and subsequently developed sinus node dysfunction (SND). To date, there are a limited number of reports of sinus node dysfunction (SND) associated with COVID-19. We describe the clinical characteristics, potential pathophysiologic mechanisms and management of COVID-19 patients who experienced de novo SND.

Keywords: COVID-19; SARS-CoV-2; bradycardic; sinus node dysfunction (SND).


Am J Med Case Rep


. 2021;9(4):263-267.
doi: 10.12691/ajmcr-9-4-15. Epub 2021 Feb 4.
Syncope Associated with Sinus Nodal Dysfunction in a COVID-19 Patient: A Case Report and Review of the Literature


Andrew V Doodnauth[SUP] 1 [/SUP], Ahmad Jallad[SUP] 2 [/SUP], Dahlia Rizk[SUP] 3 [/SUP], Emmanuel Valery[SUP] 1 [/SUP], Samy I McFarlane[SUP] 1 [/SUP]



Affiliations

Abstract

COVID-19 caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is associated with significant cardiovascular dysfunction in patients with, and without, pre-existing cardiovascular disease [1]. There are now well-documented cardiac complications of COVID-19 infection which include myocarditis, heart failure, and acute coronary syndrome [2]. There is growing evidence showing that arrhythmias are also one of the major complications of COVID-19. We report a patient with no known cardiac conduction disease who presented with syncope, positive SARS-CoV-2 PCR, who was persistently bradycardic and subsequently developed sinus node dysfunction (SND). To date, there are a limited number of reports of sinus node dysfunction (SND) associated with COVID-19. We describe the clinical characteristics, potential pathophysiologic mechanisms and management of COVID-19 patients who experienced de novo SND.

Keywords: COVID-19; SARS-CoV-2; bradycardic; sinus node dysfunction (SND).
 
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