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Am J Perinatol. Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2

tetano

Editor, Senior Moderator
Am J Perinatol. 2020 May 2. doi: 10.1055/s-0040-1710541. [Epub ahead of print]
Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2.


Buonsenso D[SUP]1[/SUP], Costa S[SUP]#[/SUP][SUP]1[/SUP], Sanguinetti M[SUP]2[/SUP], Cattani P[SUP]2[/SUP], Posteraro B[SUP]2[/SUP], Marchetti S[SUP]2[/SUP], Carducci B[SUP]1[/SUP], Lanzone A[SUP]1[/SUP], Tamburrini E[SUP]2[/SUP], Vento G[SUP]1[/SUP], Valentini P[SUP]1[/SUP].

Author information




Abstract

OBJECTIVE:

 To date, no information on late-onset infection in newborns to mother with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contracted in pregnancy are available. This study aimed to evaluate postdischarge SARS-CoV-2 status of newborns to mothers with COVID-19 in pregnancy that, at birth, were negative to SARS-CoV-2.
STUDY DESIGN:

 This is an observational study of neonates born to mothers with coronavirus disease 2019 (COVID-19).
RESULTS:

 Seven pregnant women with documented SARS-CoV-2 infection have been evaluated in our institution. One woman had a spontaneous abortion at 8 weeks of gestational age, four women recovered and are still in follow-up, and two women delivered. Two newborns were enrolled in the study. At birth and 3 days of life, newborns were negative to SARS-CoV-2. At 2-week follow-up, one newborn tested positive although asymptomatic.
CONCLUSION:

 Our findings highlight the importance of follow-up of newborns to mothers with COVID-19 in pregnancy, since they remain at risk of contracting the infection in the early period of life and long-term consequences are still unknown.
KEY POINTS:

? Newborns to mothers with coronavirus disease 2019 (COVID-19) in pregnancy can acquire the infection later after birth.. ? Newborns to mothers with COVID-19 in pregnancy need a long-term follow-up, even if they tested negative at birth.. ? Specific guidelines for the long-term follow-up of newborns to mothers with COVID-19 in pregnancy are needed..
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.



PMID:32359227DOI:10.1055/s-0040-1710541
 
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