tetano
Editor, Senior Moderator
Am J Transplant
. 2020 Jun 8.
doi: 10.1111/ajt.16120. Online ahead of print.
COVID-19 in Recent Kidney Transplant Recipients
Ashay Shingare[SUP] 1 [/SUP], Madan M Bahadur[SUP] 1 [/SUP], Shailesh Raina[SUP] 2 [/SUP]
Affiliations
Abstract
As coronavirus disease 2019 (COVID-19) pandemic spread across the globe, transplant programs suffered a setback. We report the first experience of COVID-19 infection within 1 month of living donor kidney transplant (LDKT). We describe 2 LDKT recipients who were detected positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection at day 19 and day 7 post-transplant. They had minimal symptoms at diagnosis and did not develop any respiratory complications or allograft dysfunction. Immunosuppression was de-escalated; however, nasopharyngeal swab real-time reverse transcription polymerase chain reaction (rRT-PCR) remained positive for SARS-CoV-2 for a prolonged time. Younger age, absence of other comorbidities and lower dose of anti-thymocyte globulin (ATG) used as induction possibly contributed to good outcome in our recent LDKT recipients compared with earlier published cases of recent deceased donor kidney transplant recipients with COVID-19.
This article is protected by copyright. All rights reserved.
. 2020 Jun 8.
doi: 10.1111/ajt.16120. Online ahead of print.
COVID-19 in Recent Kidney Transplant Recipients
Ashay Shingare[SUP] 1 [/SUP], Madan M Bahadur[SUP] 1 [/SUP], Shailesh Raina[SUP] 2 [/SUP]
Affiliations
- PMID: 32515085
- DOI: 10.1111/ajt.16120
Abstract
As coronavirus disease 2019 (COVID-19) pandemic spread across the globe, transplant programs suffered a setback. We report the first experience of COVID-19 infection within 1 month of living donor kidney transplant (LDKT). We describe 2 LDKT recipients who were detected positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection at day 19 and day 7 post-transplant. They had minimal symptoms at diagnosis and did not develop any respiratory complications or allograft dysfunction. Immunosuppression was de-escalated; however, nasopharyngeal swab real-time reverse transcription polymerase chain reaction (rRT-PCR) remained positive for SARS-CoV-2 for a prolonged time. Younger age, absence of other comorbidities and lower dose of anti-thymocyte globulin (ATG) used as induction possibly contributed to good outcome in our recent LDKT recipients compared with earlier published cases of recent deceased donor kidney transplant recipients with COVID-19.
This article is protected by copyright. All rights reserved.