tetano
Editor, Senior Moderator
Biochem (Mosc) Suppl Ser A Membr Cell Biol
. 2023;17(1):1-11.
doi: 10.1134/S1990747822060034. Epub 2023 Mar 29.
SARS-CoV-2 Receptors and Their Involvement in Cell Infection
P P Avdonin[SUP] 1 [/SUP], E Yu Rybakova[SUP] 1 [/SUP], S K Trufanov[SUP] 1 [/SUP], P V Avdonin[SUP] 1 [/SUP]
Affiliations
Abstract
The new coronavirus infection (COVID-19) pandemic caused by SARS-CoV-2 has many times surpassed the epidemics caused by SARS-CoV and MERS-CoV. The reason for this was the presence of sites in the protein sequence of SARS-CoV-2 that provide interaction with a broader range of receptor proteins on the host cell surface. In this review, we consider both already known receptors common to SARS-CoV and SARS-CoV-2 and new receptors specific to SARS-CoV-2.
Keywords: ACE2; ASGR1; CD147; CD209; GRP78; KREMEN1; SARS-CoV-2; cathepsin L; coronavirus; furin; heparan sulfate; neuropilin; receptors; tyrosine protein kinase AXL.
. 2023;17(1):1-11.
doi: 10.1134/S1990747822060034. Epub 2023 Mar 29.
SARS-CoV-2 Receptors and Their Involvement in Cell Infection
P P Avdonin[SUP] 1 [/SUP], E Yu Rybakova[SUP] 1 [/SUP], S K Trufanov[SUP] 1 [/SUP], P V Avdonin[SUP] 1 [/SUP]
Affiliations
- PMID: 37008884
- PMCID: PMC10050803
- DOI: 10.1134/S1990747822060034
Abstract
The new coronavirus infection (COVID-19) pandemic caused by SARS-CoV-2 has many times surpassed the epidemics caused by SARS-CoV and MERS-CoV. The reason for this was the presence of sites in the protein sequence of SARS-CoV-2 that provide interaction with a broader range of receptor proteins on the host cell surface. In this review, we consider both already known receptors common to SARS-CoV and SARS-CoV-2 and new receptors specific to SARS-CoV-2.
Keywords: ACE2; ASGR1; CD147; CD209; GRP78; KREMEN1; SARS-CoV-2; cathepsin L; coronavirus; furin; heparan sulfate; neuropilin; receptors; tyrosine protein kinase AXL.