tetano
Editor, Senior Moderator
BMC Infect Dis
. 2021 Dec 20;21(1):1271.
doi: 10.1186/s12879-021-06970-3.
Six-month follow-up of functional status in discharged patients with coronavirus disease 2019
Hou-Wei Du[SUP] #[/SUP][SUP] 1 2 [/SUP], Shuang-Fang Fang[SUP] #[/SUP][SUP] 1 2 [/SUP], Sang-Ru Wu[SUP] #[/SUP][SUP] 1 2 [/SUP], Xiao-Ling Chen[SUP] #[/SUP][SUP] 3 [/SUP], Jun-Nian Chen[SUP] 4 [/SUP], Yi-Xian Zhang[SUP] 5 [/SUP], Hua-Yao Huang[SUP] 5 [/SUP], Han-Han Lei[SUP] 1 2 [/SUP], Rong-Hua Chen[SUP] 1 2 [/SUP], Xiao-Bin Pan[SUP] 6 [/SUP], Xiao-Qing Li[SUP] 7 [/SUP], Pin-Cang Xia[SUP] 7 [/SUP], Zhen-Yang Zheng[SUP] 1 2 [/SUP], Ling-Luo[SUP] 1 2 [/SUP], Hai-Long Lin[SUP] 8 [/SUP], Li-Min Chen[SUP] 9 [/SUP], Nan Liu[SUP] 10 11 [/SUP], Fujian Medical Team Support Wuhan for COVID19
Affiliations
Abstract
Background: The long-term functional outcome of discharged patients with coronavirus disease 2019 (COVID-19) remains unresolved. We aimed to describe a 6-month follow-up of functional status of COVID-19 survivors.
Methods: We reviewed the data of COVID-19 patients who had been consecutively admitted to the Tumor Center of Union Hospital (Wuhan, China) between 15 February and 14 March 2020. We quantified a 6-month functional outcome reflecting symptoms and disability in COVID-19 survivors using a post-COVID-19 functional status scale ranging from 0 to 4 (PCFS). We examined the risk factors for the incomplete functional status defined as a PCFS > 0 at a 6-month follow-up after discharge.
Results: We included a total of 95 COVID-19 survivors with a median age of 62 (IQR 53-69) who had a complete functional status (PCFS grade 0) at baseline in this retrospective observational study. At 6-month follow-up, 67 (70.5%) patients had a complete functional outcome (grade 0), 9 (9.5%) had a negligible limited function (grade 1), 12 (12.6%) had a mild limited function (grade 2), 7 (7.4%) had moderate limited function (grade 3). Univariable logistic regression analysis showed a significant association between the onset symptoms of muscle or joint pain and an increased risk of incomplete function (unadjusted OR 4.06, 95% CI 1.33-12.37). This association remained after adjustment for age and admission delay (adjusted OR 3.39, 95% CI 1.06-10.81, p = 0.039).
Conclusions: A small proportion of discharged COVID-19 patients may have an incomplete functional outcome at a 6-month follow-up; intervention strategies are required.
Keywords: Coronavirus disease 2019; Follow-up; Functional outcome.
. 2021 Dec 20;21(1):1271.
doi: 10.1186/s12879-021-06970-3.
Six-month follow-up of functional status in discharged patients with coronavirus disease 2019
Hou-Wei Du[SUP] #[/SUP][SUP] 1 2 [/SUP], Shuang-Fang Fang[SUP] #[/SUP][SUP] 1 2 [/SUP], Sang-Ru Wu[SUP] #[/SUP][SUP] 1 2 [/SUP], Xiao-Ling Chen[SUP] #[/SUP][SUP] 3 [/SUP], Jun-Nian Chen[SUP] 4 [/SUP], Yi-Xian Zhang[SUP] 5 [/SUP], Hua-Yao Huang[SUP] 5 [/SUP], Han-Han Lei[SUP] 1 2 [/SUP], Rong-Hua Chen[SUP] 1 2 [/SUP], Xiao-Bin Pan[SUP] 6 [/SUP], Xiao-Qing Li[SUP] 7 [/SUP], Pin-Cang Xia[SUP] 7 [/SUP], Zhen-Yang Zheng[SUP] 1 2 [/SUP], Ling-Luo[SUP] 1 2 [/SUP], Hai-Long Lin[SUP] 8 [/SUP], Li-Min Chen[SUP] 9 [/SUP], Nan Liu[SUP] 10 11 [/SUP], Fujian Medical Team Support Wuhan for COVID19
Affiliations
- PMID: 34930161
- DOI: 10.1186/s12879-021-06970-3
Abstract
Background: The long-term functional outcome of discharged patients with coronavirus disease 2019 (COVID-19) remains unresolved. We aimed to describe a 6-month follow-up of functional status of COVID-19 survivors.
Methods: We reviewed the data of COVID-19 patients who had been consecutively admitted to the Tumor Center of Union Hospital (Wuhan, China) between 15 February and 14 March 2020. We quantified a 6-month functional outcome reflecting symptoms and disability in COVID-19 survivors using a post-COVID-19 functional status scale ranging from 0 to 4 (PCFS). We examined the risk factors for the incomplete functional status defined as a PCFS > 0 at a 6-month follow-up after discharge.
Results: We included a total of 95 COVID-19 survivors with a median age of 62 (IQR 53-69) who had a complete functional status (PCFS grade 0) at baseline in this retrospective observational study. At 6-month follow-up, 67 (70.5%) patients had a complete functional outcome (grade 0), 9 (9.5%) had a negligible limited function (grade 1), 12 (12.6%) had a mild limited function (grade 2), 7 (7.4%) had moderate limited function (grade 3). Univariable logistic regression analysis showed a significant association between the onset symptoms of muscle or joint pain and an increased risk of incomplete function (unadjusted OR 4.06, 95% CI 1.33-12.37). This association remained after adjustment for age and admission delay (adjusted OR 3.39, 95% CI 1.06-10.81, p = 0.039).
Conclusions: A small proportion of discharged COVID-19 patients may have an incomplete functional outcome at a 6-month follow-up; intervention strategies are required.
Keywords: Coronavirus disease 2019; Follow-up; Functional outcome.