tetano
Editor, Senior Moderator
BMC Med
. 2021 Mar 15;19(1):77.
doi: 10.1186/s12916-021-01954-1.
A follow-up study shows that recovered patients with re-positive PCR test in Wuhan may not be infectious
Xiaomin Wu[SUP] #[/SUP][SUP] 1 [/SUP], Zengmiao Wang[SUP] #[/SUP][SUP] 2 [/SUP], Zhenyu He[SUP] #[/SUP][SUP] 3 [/SUP], Yapin Li[SUP] #[/SUP][SUP] 4 [/SUP], Yating Wu[SUP] 1 [/SUP], Huaiji Wang[SUP] 1 [/SUP], Yonghong Liu[SUP] 5 [/SUP], Fanghua Hao[SUP] 6 [/SUP], Huaiyu Tian[SUP] #[/SUP][SUP] 5 [/SUP]
Affiliations
Abstract
Background: Previous studies showed that recovered coronavirus disease 2019 (COVID-19) patients can have a subsequent positive polymerase chain reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after they are discharged from the hospital. Understanding the epidemiological characteristics of recovered COVID-19 patients who have a re-positive test is vital for preventing a second wave of COVID-19.
Methods: This retrospective study analyzed the epidemiological and clinical features of 20,280 COVID-19 patients from multiple centers in Wuhan who had a positive PCR test between December 31, 2019, and August 4, 2020. The RT-PCR test results for 4079 individuals who had close contact with the re-positive cases were also obtained.
Results: In total, 2466 (12.16%) of the 20,280 patients had a re-positive SARS-CoV-2 PCR test after they were discharged from the hospital, and 4079 individuals had close contact with members of this patient group. All of these 4079 individuals had a negative SARS-CoV-2 PCR test.
Conclusions: This retrospective study in Wuhan analyzed the basic characteristics of recovered COVID-19 patients with re-positive PCR test and found that these cases may not be infectious.
Keywords: COVID-19; Close contact; Repeat positive; Subsequent infection.
. 2021 Mar 15;19(1):77.
doi: 10.1186/s12916-021-01954-1.
A follow-up study shows that recovered patients with re-positive PCR test in Wuhan may not be infectious
Xiaomin Wu[SUP] #[/SUP][SUP] 1 [/SUP], Zengmiao Wang[SUP] #[/SUP][SUP] 2 [/SUP], Zhenyu He[SUP] #[/SUP][SUP] 3 [/SUP], Yapin Li[SUP] #[/SUP][SUP] 4 [/SUP], Yating Wu[SUP] 1 [/SUP], Huaiji Wang[SUP] 1 [/SUP], Yonghong Liu[SUP] 5 [/SUP], Fanghua Hao[SUP] 6 [/SUP], Huaiyu Tian[SUP] #[/SUP][SUP] 5 [/SUP]
Affiliations
- PMID: 33715626
- DOI: 10.1186/s12916-021-01954-1
Abstract
Background: Previous studies showed that recovered coronavirus disease 2019 (COVID-19) patients can have a subsequent positive polymerase chain reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after they are discharged from the hospital. Understanding the epidemiological characteristics of recovered COVID-19 patients who have a re-positive test is vital for preventing a second wave of COVID-19.
Methods: This retrospective study analyzed the epidemiological and clinical features of 20,280 COVID-19 patients from multiple centers in Wuhan who had a positive PCR test between December 31, 2019, and August 4, 2020. The RT-PCR test results for 4079 individuals who had close contact with the re-positive cases were also obtained.
Results: In total, 2466 (12.16%) of the 20,280 patients had a re-positive SARS-CoV-2 PCR test after they were discharged from the hospital, and 4079 individuals had close contact with members of this patient group. All of these 4079 individuals had a negative SARS-CoV-2 PCR test.
Conclusions: This retrospective study in Wuhan analyzed the basic characteristics of recovered COVID-19 patients with re-positive PCR test and found that these cases may not be infectious.
Keywords: COVID-19; Close contact; Repeat positive; Subsequent infection.