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Br J Dermatol . Co-Reactivation of Human Herpesvirus alpha Subfamily (HSV Ⅰ and VZV) in Critically Ill Patient with COVID-19

tetano

Editor, Senior Moderator
Br J Dermatol


. 2020 Aug 13.
doi: 10.1111/bjd.19484. Online ahead of print.
Co-Reactivation of Human Herpesvirus alpha Subfamily (HSV Ⅰ and VZV) in Critically Ill Patient with COVID-19


R Xu[SUP] 1 [/SUP], Y Zhou[SUP] 2 [/SUP], L Cai[SUP] 3 [/SUP], L Wang[SUP] 4 [/SUP], J Han[SUP] 1 [/SUP], X Yang[SUP] 2 [/SUP], J Chen[SUP] 2 [/SUP], J Chen[SUP] 2 [/SUP], C Ma[SUP] 1 [/SUP], L Shen[SUP] 2 [/SUP]



Affiliations

Abstract

Coronavirus disease 2019 (COVID-19) is already well known globally[SUP]1[/SUP] . The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 infection) causes a spectrum of severe clinical manifestations, which leads to a high rate of intensive care unit (ICU) admissions and mortality. We report a first case of COVID-19 with reactivation of human herpesvirus (HHV) alpha subfamily (herpes simplex virus I [HSV Ⅰ] and varicella-zoster virus [VZV]). Due to the immunosuppressive state associated with COVID-19, infection of the HHV alpha subfamily (HSV Ⅰ and VZV) could be potentially life threatening.

Keywords: critical ill patient with COVID-19; herpes simplex Ⅰ (HSV Ⅰ); reactivation of human herpesvirus alpha subfamily; secondary infection; varicella-zoster virus (VZV).
 
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