tetano
Editor, Senior Moderator
Cell Host Microbe
. 2020 Dec 9;28(6):778-779.
doi: 10.1016/j.chom.2020.11.008.
FRETing over SARS-CoV-2: Conformational Dynamics of the Spike Glycoprotein
Vitor Hugo B Serr?o[SUP] 1 [/SUP], Jeffrey E Lee[SUP] 2 [/SUP]
Affiliations
Abstract
In this issue of Cell Host & Microbe, Lu et al. utilize single-molecule FRET to reveal the conformation dynamics of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, showing transitions from a closed ground state to the open receptor-accessible conformation via an on-path intermediate. These insights into spike conformations will facilitate rational immunogen design.
. 2020 Dec 9;28(6):778-779.
doi: 10.1016/j.chom.2020.11.008.
FRETing over SARS-CoV-2: Conformational Dynamics of the Spike Glycoprotein
Vitor Hugo B Serr?o[SUP] 1 [/SUP], Jeffrey E Lee[SUP] 2 [/SUP]
Affiliations
- PMID: 33301717
- PMCID: PMC7725053
- DOI: 10.1016/j.chom.2020.11.008
Abstract
In this issue of Cell Host & Microbe, Lu et al. utilize single-molecule FRET to reveal the conformation dynamics of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, showing transitions from a closed ground state to the open receptor-accessible conformation via an on-path intermediate. These insights into spike conformations will facilitate rational immunogen design.