tetano
Editor, Senior Moderator
Chest
. 2020 Oct;158(4):e139-e142.
doi: 10.1016/j.chest.2020.05.579.
Severe Coronavirus Disease 2019 Infection in an Adolescent Patient After Hematopoietic Stem Cell Transplantation
Grace Fisler[SUP] 1 [/SUP], Abraham Haimed[SUP] 2 [/SUP], Carolyn Fein Levy[SUP] 3 [/SUP], Jessica Stiles[SUP] 3 [/SUP], Christine A Capone[SUP] 1 [/SUP], Jonathan D Fish[SUP] 3 [/SUP], Joel A Brochstein[SUP] 3 [/SUP], Matthew D Taylor[SUP] 4 [/SUP]
Affiliations
Abstract
Infection with the severe acute respiratory syndrome coronavirus 2 causes severe acute lung injury in approximately 5% of infected adults, but few reports have been made of severe pediatric disease. We present an adolescent patient who contracted severe acute respiratory syndrome coronavirus 2 one week after a paternal haplo-identical hematopoietic stem cell transplant, with development of severe hyperferritinemic acute lung injury and macrophage activation-like syndrome. We present her case and a comparison of her laboratory data with those of a cohort of pediatric patients with coronavirus disease 2019 without severe disease.
Keywords: COVID-19; bone marrow transplant; macrophage activation-like syndrome; pediatric acute respiratory distress syndrome; pediatrics.
. 2020 Oct;158(4):e139-e142.
doi: 10.1016/j.chest.2020.05.579.
Severe Coronavirus Disease 2019 Infection in an Adolescent Patient After Hematopoietic Stem Cell Transplantation
Grace Fisler[SUP] 1 [/SUP], Abraham Haimed[SUP] 2 [/SUP], Carolyn Fein Levy[SUP] 3 [/SUP], Jessica Stiles[SUP] 3 [/SUP], Christine A Capone[SUP] 1 [/SUP], Jonathan D Fish[SUP] 3 [/SUP], Joel A Brochstein[SUP] 3 [/SUP], Matthew D Taylor[SUP] 4 [/SUP]
Affiliations
- PMID: 33036110
- DOI: 10.1016/j.chest.2020.05.579
Abstract
Infection with the severe acute respiratory syndrome coronavirus 2 causes severe acute lung injury in approximately 5% of infected adults, but few reports have been made of severe pediatric disease. We present an adolescent patient who contracted severe acute respiratory syndrome coronavirus 2 one week after a paternal haplo-identical hematopoietic stem cell transplant, with development of severe hyperferritinemic acute lung injury and macrophage activation-like syndrome. We present her case and a comparison of her laboratory data with those of a cohort of pediatric patients with coronavirus disease 2019 without severe disease.
Keywords: COVID-19; bone marrow transplant; macrophage activation-like syndrome; pediatric acute respiratory distress syndrome; pediatrics.