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CIDRAP ANTIMICROBIAL RESISTANCE SCAN: Compliance and MRSA clearance ; Costs of MRSA care

Shiloh

Editor, Senior Moderator
Source: http://www.cidrap.umn.edu/news-perspective/2016/07/antimicrobial-resistance-scan-jul-29-2016

Antimicrobial Resistance Scan for Jul 29, 2016
Compliance and MRSA clearance; Costs of MRSA care
Filed Under:
Antimicrobial Stewardship; MRSA; Pneumonia
[h=3]Compliance with treatment protocols may speed MRSA clearance[/h] A new study has found that better compliance with treatment protocols can lead to quicker clearance of soft skin and tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA).
The study, published in Infection Control and Hospital Epidemiology, was a randomized control trial conducted among members of 223 households affected by community-onset MRSA, which can be commonly transmitted among household members. The trial split the families into three groups: One group received only education on personal and household hygiene, a second received education along with decolonization treatment (consisting of a topical antibiotic ointment and an antiseptic body wash) and daily reminders, and a third received education with treatment but no reminders.
At the end of the trial, the researchers found that there was no significant difference in the time it took the MRSA infections to clear between the group that received education only and the groups that received treatment. But on a secondary analysis, they found that in the households that were 100% compliant with treatment protocols and decolonization strategies, the bacteria cleared more quickly than it did in non-compliant households (23 days compared with 27 days).
The researchers said their findings indicate clinicians treating patients with skin and soft tissue MRSA infections should emphasize the importance of full compliance with decolonization treatment, but also spend time educating patients on good hygiene measures, which can reduce household spread.
Jul 28 Infect Control Hosp Epidemiol study
Jul 28 Society for Healthcare Epidemiology of America news release

[h=3]MRSA carries economic burden in pneumonia patients[/h] A research team in Japan reported that infection with MRSA carries a high cost. The team reported their findings on the clinical and financial impacts of MRSA infections in patients hospitalized with community-onset pneumonia in the American Journal of Infection Control.
Using data from a nationwide administrative claims database, the researchers analyzed pneumonia patients at 1,063 acute care hospitals in Japan, comparing 634 patients who received anti-MRSA drugs against a control group of 87,427 patients. Adjusting for risk, they found that patients who received anti-MRSA medications had longer hospital stays (21 days vs. 14 days), spent more on antibiotics ($756 vs $172), and had higher hospital costs ($8,741 vs. $5,063).
The researchers say the findings should spur further research on the quantitative effects of multi-drug resistant bacterial infections on healthcare resources, and could inform future policies.
Jul 27 Am J Infect Control study
 
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