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Clin Exp Vaccine Res . The relationship between COVID-19 vaccination attitudes and COVID-19-related parameters with mental health problems: the pote

tetano

Editor, Senior Moderator
Clin Exp Vaccine Res


. 2026 Jan;15(1):24-34.
doi: 10.7774/cevr.2026.15.e4. Epub 2025 Nov 12.
The relationship between COVID-19 vaccination attitudes and COVID-19-related parameters with mental health problems: the potential role of behavioral issues

Caner Mutlu[SUP] 1 [/SUP], Emine Büşra Ölmez[SUP] 2 [/SUP], Celal Yeşilkaya[SUP] 3 [/SUP], Hande Kırışman Keleş[SUP] 4 [/SUP], Esra Rabia Taşpolat[SUP] 4 [/SUP], Serkan Turan[SUP] 1 [/SUP], Şafak Eray Çamlı[SUP] 1 [/SUP]


Affiliations
Abstract

Purpose: This study aimed to examine the relationship between coronavirus disease 2019 (COVID-19) vaccination status and psychiatric symptoms, illness perceptions, avoidance behaviors, and familial vaccination patterns in adolescents referred to a child and adolescent psychiatry outpatient clinic.
Materials and methods: This cross-sectional observational study included adolescents (n=168) aged 12-18 years. Participants were categorized as vaccinated (n=74, 44%) or unvaccinated (n=94, 56%). Data were collected using validated instruments, including the Coronavirus Anxiety Scale, Clinical Global Impression-Severity, Strengths and Difficulties Questionnaire-Parent version, and several scales evaluating COVID-19 perceptions, control beliefs, avoidance attitudes, and vaccine attitudes. Mann-Whitney U and χ[SUP]2[/SUP] tests were used for group comparisons. Binary logistic regression was performed to identify predictors of vaccination status.
Results: Vaccinated adolescents were significantly older, more likely female, and more frequently had vaccinated siblings and mothers (p<0.05). They reported higher behavioral avoidance and more positive attitudes toward vaccination, while displaying lower hyperactivity/inattention symptoms (p<0.05). Logistic regression revealed that female gender (odds ratio [OR], 5.11; 95% confidence interval [CI], 1.67-15.64), older age (OR, 1.82; 95% CI, 1.38-2.40), sibling vaccination (OR, 4.53; 95% CI, 1.55-13.25), and increased peer problems (OR, 1.40; 95% CI, 1.02-1.93) significantly predicted vaccination status (p<0.05).
Conclusion: In psychiatrically referred adolescents, COVID-19 vaccination is associated with demographic, familial, and psychological variables. Positive vaccine attitudes, behavioral avoidance, and family modeling increase the likelihood of vaccination, whereas hyperactivity/inattention symptoms may reduce it.

Keywords: Adolescents; COVID-19; Mental health; Vaccination.

 
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