tetano
Editor, Senior Moderator
Clin Res Hepatol Gastroenterol. 2020 Apr 27. pii: S2210-7401(20)30105-4. doi: 10.1016/j.clinre.2020.04.002. [Epub ahead of print]
Diarrhea: An underestimated symptom in Coronavirus disease 2019.
Klopfenstein T[SUP]1[/SUP], Kadiane-Oussou NJ[SUP]2[/SUP], Royer PY[SUP]3[/SUP], Toko L[SUP]4[/SUP], Gendrin V[SUP]5[/SUP], Zayet S[SUP]6[/SUP].
Author information
Abstract
In a retrospective study in the Nord Franche-Comt? hospital conducted between March 1st and March 17th 2020, and compared to the review of Li et al., diarrhea was a main symptom in patients with COVID-19. Out of the 114 patients, 55 (48%) had diarrhea; it was the fifth most common symptom. In the group of patients with diarrhea, the median age was 56 years (?18) and 32 (58%) were female. Only 2 patients (3.6%) had a past history of inflammatory bowel disease. Fifty-six percent of patients (n=30/54) were hospitalised. Diarrhea appeared 4.5 days (?1.8) after the onset of the first other symptoms in COVID-19. Of the 55 patients with diarrhea, 29 (52.7%) had at least one simultaneous gastrointestinal (GI) symptom other than diarrhea. Twenty-five patients (45.5%) had nausea, 19 patients (34.5%) had abdominal pain and 9 (16.3%) had vomiting. Myalgia, sore throat, sneezing and the other GI symptoms were statistically more frequent in the group with diarrhea than in the group without diarrhea (P<0.05).
Copyright ? 2020 Elsevier Masson SAS. All rights reserved.
PMID:32371006DOI:10.1016/j.clinre.2020.04.002
Diarrhea: An underestimated symptom in Coronavirus disease 2019.
Klopfenstein T[SUP]1[/SUP], Kadiane-Oussou NJ[SUP]2[/SUP], Royer PY[SUP]3[/SUP], Toko L[SUP]4[/SUP], Gendrin V[SUP]5[/SUP], Zayet S[SUP]6[/SUP].
Author information
Abstract
In a retrospective study in the Nord Franche-Comt? hospital conducted between March 1st and March 17th 2020, and compared to the review of Li et al., diarrhea was a main symptom in patients with COVID-19. Out of the 114 patients, 55 (48%) had diarrhea; it was the fifth most common symptom. In the group of patients with diarrhea, the median age was 56 years (?18) and 32 (58%) were female. Only 2 patients (3.6%) had a past history of inflammatory bowel disease. Fifty-six percent of patients (n=30/54) were hospitalised. Diarrhea appeared 4.5 days (?1.8) after the onset of the first other symptoms in COVID-19. Of the 55 patients with diarrhea, 29 (52.7%) had at least one simultaneous gastrointestinal (GI) symptom other than diarrhea. Twenty-five patients (45.5%) had nausea, 19 patients (34.5%) had abdominal pain and 9 (16.3%) had vomiting. Myalgia, sore throat, sneezing and the other GI symptoms were statistically more frequent in the group with diarrhea than in the group without diarrhea (P<0.05).
Copyright ? 2020 Elsevier Masson SAS. All rights reserved.
PMID:32371006DOI:10.1016/j.clinre.2020.04.002