tetano
Editor, Senior Moderator
Cureus
. 2022 Mar 10;14(3):e23046.
doi: 10.7759/cureus.23046. eCollection 2022 Mar.
Multisystem Inflammatory Syndrome of a Neonate From a COVID-19-Infected Mother: A Case Report
Abdul Malek[SUP] 1 [/SUP], Mukesh Khadga[SUP] 2 [/SUP], Md Nurnobi Zahid[SUP] 2 [/SUP], Sanjida Mojib[SUP] 2 [/SUP], Reena Debnath[SUP] 2 [/SUP], Sheela Khan[SUP] 3 [/SUP], Mainul Haque[SUP] 4 [/SUP], Brian Godman[SUP] 5 6 7 [/SUP], Salequl Islam[SUP] 8 [/SUP]
Affiliations
Abstract
In neonates, the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 - COVID-19) is lower. There is the potential for vertical transmission of SARS-CoV-2. To date, only a few reports suggest this possibility. Neonates usually have mild symptoms, but some develop multisystem involvement, which is a concern. COVID-19 infections have been reported both in pregnant women and their neonates. However, the evidence of vertical or horizontal transmission modes has not been fully established. We recorded a case study where a 33-year-old mother was tested positive for COVID-19 infection by RT-PCR during her 27[SUP]th[/SUP] week of gestation and needed ventilator support for her respiratory distress at that time for 11 days. Subsequently, she gave birth to a female baby at the 35[SUP]th[/SUP] week via a lower uterine segment cesarean section. The neonate manifested a severe multisystem inflammatory syndrome associated with her possible COVID-19 infection. Sharing her uncommon clinical presentation, immunological syndrome, and disease outcome are noteworthy for similar unforeseen pediatric case management to help guide future investigations and care.
Keywords: covid-19; multisystem inflammatory syndrome; neonate; rt-pcr; sars-cov-2.
. 2022 Mar 10;14(3):e23046.
doi: 10.7759/cureus.23046. eCollection 2022 Mar.
Multisystem Inflammatory Syndrome of a Neonate From a COVID-19-Infected Mother: A Case Report
Abdul Malek[SUP] 1 [/SUP], Mukesh Khadga[SUP] 2 [/SUP], Md Nurnobi Zahid[SUP] 2 [/SUP], Sanjida Mojib[SUP] 2 [/SUP], Reena Debnath[SUP] 2 [/SUP], Sheela Khan[SUP] 3 [/SUP], Mainul Haque[SUP] 4 [/SUP], Brian Godman[SUP] 5 6 7 [/SUP], Salequl Islam[SUP] 8 [/SUP]
Affiliations
- PMID: 35419241
- PMCID: PMC8994695
- DOI: 10.7759/cureus.23046
Abstract
In neonates, the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 - COVID-19) is lower. There is the potential for vertical transmission of SARS-CoV-2. To date, only a few reports suggest this possibility. Neonates usually have mild symptoms, but some develop multisystem involvement, which is a concern. COVID-19 infections have been reported both in pregnant women and their neonates. However, the evidence of vertical or horizontal transmission modes has not been fully established. We recorded a case study where a 33-year-old mother was tested positive for COVID-19 infection by RT-PCR during her 27[SUP]th[/SUP] week of gestation and needed ventilator support for her respiratory distress at that time for 11 days. Subsequently, she gave birth to a female baby at the 35[SUP]th[/SUP] week via a lower uterine segment cesarean section. The neonate manifested a severe multisystem inflammatory syndrome associated with her possible COVID-19 infection. Sharing her uncommon clinical presentation, immunological syndrome, and disease outcome are noteworthy for similar unforeseen pediatric case management to help guide future investigations and care.
Keywords: covid-19; multisystem inflammatory syndrome; neonate; rt-pcr; sars-cov-2.