tetano
Editor, Senior Moderator
Transpl Infect Dis. 2012 Sep 26. doi: 10.1111/tid.12004. [Epub ahead of print]
Efficient control of pandemic 2009 H1N1 virus infection with intravenous zanamivir despite the lack of immune function.
Ghosh S, Adams O, Schuster FR, Borkhardt A, Meisel R.
Source
Department of Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Medical Faculty, Heinrich-Heine-Universit?t, D?sseldorf, Germany.
Abstract
A teenager who acquired 2009 H1N1 influenza A lower respiratory tract infection during total bone marrow and lymphoid aplasia, in the setting of human leukocyte antigen-haploidentical hematopoietic stem cell transplantation, was successfully treated with intravenous zanamivir. This case demonstrates efficient control of pandemic influenza infection by intravenous zanamivir in the absence of any functional immune system, thus suggesting profound antiviral activity.
? 2012 John Wiley & Sons A/S.
PMID:
23013415
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23013415
Efficient control of pandemic 2009 H1N1 virus infection with intravenous zanamivir despite the lack of immune function.
Ghosh S, Adams O, Schuster FR, Borkhardt A, Meisel R.
Source
Department of Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Medical Faculty, Heinrich-Heine-Universit?t, D?sseldorf, Germany.
Abstract
A teenager who acquired 2009 H1N1 influenza A lower respiratory tract infection during total bone marrow and lymphoid aplasia, in the setting of human leukocyte antigen-haploidentical hematopoietic stem cell transplantation, was successfully treated with intravenous zanamivir. This case demonstrates efficient control of pandemic influenza infection by intravenous zanamivir in the absence of any functional immune system, thus suggesting profound antiviral activity.
? 2012 John Wiley & Sons A/S.
PMID:
23013415
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23013415