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Emerg Infect Dis . Characteristics of and Deaths among 333 Persons with Tuberculosis and COVID-19 in Cross-Sectional Sample from 25 Jurisdictions, U

tetano

Editor, Senior Moderator
Emerg Infect Dis


. 2023 Aug 30;29(10).
doi: 10.3201/eid2910.230286. Online ahead of print.
Characteristics of and Deaths among 333 Persons with Tuberculosis and COVID-19 in Cross-Sectional Sample from 25 Jurisdictions, United States

Scott A Nabity, Suzanne M Marks, Neela D Goswami, Shona R Smith, Evan Timme, Sandy F Price, Lon Gross, Julie L Self, Katelynne Gardner Toren, Masahiro Narita, Donna H Wegener, Shu-Hua Wang; National Tuberculosis Controllers Association/CDC TB-COVID-19 Collaboration1
Abstract

Little is known about co-occurring tuberculosis (TB) and COVID-19 in low TB incidence settings. We obtained a cross-section of 333 persons in the United States co-diagnosed with TB and COVID-19 within 180 days and compared them to 4,433 persons with TB only in 2020 and 18,898 persons with TB during 2017‒2019. Across both comparison groups, a higher proportion of persons with TB-COVID-19 were Hispanic, were long-term care facility residents, and had diabetes. When adjusted for age, underlying conditions, and TB severity, COVID-19 co-infection was not statistically associated with death compared with TB infection only in 2020 (adjusted prevalence ratio 1.0 [95% CI 0.8‒1.4]). Among TB-COVID-19 patients, death was associated with a shorter interval between TB and COVID-19 diagnoses, older age, and being immunocompromised (non-HIV). TB-COVID-19 deaths in the United States appear to be concentrated in subgroups sharing characteristics known to increase risk for death from either disease alone.

Keywords: COVID-19; SARS-CoV-2; United States; bacteria; bacterial infection; coronavirus disease; respiratory infections; severe acute respiratory syndrome coronavirus 2; tuberculosis and other mycobacteria; vaccine-preventable diseases; viruses; zoonoses.
 
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