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Emerg Infect Dis. Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus

Giuseppe

Emeritus
Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus (Emerg Infect Dis., abstract, edited)


[Source: US Centers for Disease Control and Prevention, Emerging Infectious Diseases Journal, full PDF Document (LINK). Edited.]

DOI: 10.3201/eid1611.100361

Suggested citation for this article: Bhoumik P, Hughes AL. Reassortment of ancient neuraminidase and recent hemagglutinin in pandemic (H1N1) 2009 virus. Emerg Infect Dis. 2010 Nov; [Epub ahead of print]

Reassortment of Ancient Neuraminidase and Recent Hemagglutinin in Pandemic (H1N1) 2009 Virus

Priyasma Bhoumik and Austin L. Hughes

Author affiliation: University of South Carolina, Columbia, South Carolina, USA


Sequence analyses show that the outbreak of pandemic (H1N1) 2009 resulted from the spread of a recently derived hemagglutinin through a population of ancient and more diverse neuraminidase segments. This pattern implies reassortment and suggests that the novel form of hemagglutinin conferred a selective advantage.

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