tetano
Editor, Senior Moderator
Epidemics
. 2021 Jan 21;34:100437.
doi: 10.1016/j.epidem.2021.100437. Online ahead of print.
A model for COVID-19 with isolation, quarantine and testing as control measures
M S Aronna[SUP] 1 [/SUP], R Guglielmi[SUP] 2 [/SUP], L M Moschen[SUP] 3 [/SUP]
Affiliations
Abstract
In this article we propose a compartmental model for the dynamics of Coronavirus Disease 2019 (COVID-19). We take into account the presence of asymptomatic infections and the main policies that have been adopted so far to contain the epidemic: social distancing, isolation of a portion of the population, quarantine for confirmed cases and testing. We refer to quarantine as strict isolation, and it is applied to confirmed infected cases. In the proposed model, the proportion of people in isolation, the level of contact reduction and the testing rate are control parameters that can vary in time, representing policies that evolve in different stages. We obtain an explicit expression for the basic reproduction number R[SUB]0[/SUB] in terms of the parameters of the disease and of the control policies. In this way we can quantify the effect that isolation and testing have in the evolution of the epidemic. We present a series of simulations to illustrate different realistic scenarios. From the expression of R[SUB]0[/SUB] and the simulations we conclude that isolation (social distancing) and testing among asymptomatic cases are fundamental actions to control the epidemic, and the stricter these measures are and the sooner they are implemented, the more effective they are in flattening the curve of infections. Additionally, we show that people that remain in isolation significantly reduce their probability of contagion, so risk groups should be recommended to maintain a low contact rate during the course of the epidemic.
Keywords: COVID-19; Epidemiological modeling; Quarantine; SEIR; Testing.
. 2021 Jan 21;34:100437.
doi: 10.1016/j.epidem.2021.100437. Online ahead of print.
A model for COVID-19 with isolation, quarantine and testing as control measures
M S Aronna[SUP] 1 [/SUP], R Guglielmi[SUP] 2 [/SUP], L M Moschen[SUP] 3 [/SUP]
Affiliations
- PMID: 33540378
- DOI: 10.1016/j.epidem.2021.100437
Abstract
In this article we propose a compartmental model for the dynamics of Coronavirus Disease 2019 (COVID-19). We take into account the presence of asymptomatic infections and the main policies that have been adopted so far to contain the epidemic: social distancing, isolation of a portion of the population, quarantine for confirmed cases and testing. We refer to quarantine as strict isolation, and it is applied to confirmed infected cases. In the proposed model, the proportion of people in isolation, the level of contact reduction and the testing rate are control parameters that can vary in time, representing policies that evolve in different stages. We obtain an explicit expression for the basic reproduction number R[SUB]0[/SUB] in terms of the parameters of the disease and of the control policies. In this way we can quantify the effect that isolation and testing have in the evolution of the epidemic. We present a series of simulations to illustrate different realistic scenarios. From the expression of R[SUB]0[/SUB] and the simulations we conclude that isolation (social distancing) and testing among asymptomatic cases are fundamental actions to control the epidemic, and the stricter these measures are and the sooner they are implemented, the more effective they are in flattening the curve of infections. Additionally, we show that people that remain in isolation significantly reduce their probability of contagion, so risk groups should be recommended to maintain a low contact rate during the course of the epidemic.
Keywords: COVID-19; Epidemiological modeling; Quarantine; SEIR; Testing.