Giuseppe
Emeritus
New Delhi metallo-beta-lactamase 1?producing Enterobacteriaceae: emergence and response in Europe (Euro Surveill., abstract, edited)
[Source: Eurosurveillance, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19716">Eurosurveillance - View Article</cite>. Abstract, edited.]
Eurosurveillance, Volume 15, Issue 46, 18 November 2010
Research articles
New Delhi metallo-beta-lactamase 1?producing Enterobacteriaceae: emergence and response in Europe
M. J. Struelens 1, D L Monnet 1, A P Magiorakos 1, F Santos O?Connor 1, J Giesecke 1, the European NDM-1 Survey Participants 2
1. European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden
2. The European NDM-1 Survey Participants are listed at the end of the article
Citation style for this article: Struelens MJ, Monnet DL, Magiorakos AP, Santos O?Connor F, Giesecke J, the European NDM-1 Survey Participants. New Delhi metallo-beta-lactamase 1?producing Enterobacteriaceae: emergence and response in Europe. Euro Surveill. 2010;15(46)
ii=19716. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19716
Date of submission: 08 October 2010
Acquired carbapenemases confer extensive antibiotic resistance to Enterobacteriaceae and represent a public health threat. A novel acquired carbapenemase, New Delhi metallo-beta-lactamase 1 (NDM-1), has recently been described in the United Kingdom and Sweden, mostly in patients who had received care on the Indian subcontinent. We conducted a survey among 29 European countries (the European Union Member States, Iceland and Norway) to gather information on the spread of NDM-1-producing Enterobacteriaceae in Europe, on public health responses and on available national guidance on detection, surveillance and control. A total of 77 cases were reported from 13 countries from 2008 to 2010. Klebsiella pneumoniae was the most frequently reported species with 54%. Among 55 cases with recorded travel history, 31 had previously travelled or been admitted to a hospital in India or Pakistan and five had been hospitalised in the Balkan region. Possible nosocomial acquisition accounted for 13 of 77 cases. National guidance on NDM-1 detection was available in 14 countries and on NDM-1 control in 11 countries. In conclusion, NDM-1 is spreading across Europe, where it is frequently linked to a history of healthcare abroad, but also to emerging nosocomial transmission. National guidance in response to the threat of carbapenemase-producing Enterobacteriaceae is available in approximately half of the surveyed European countries. Surveillance of carbapenemase- producing Enterobacteriaceae must be enhanced in Europe and effective control measures identified and implemented.
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[Source: Eurosurveillance, full text: <cite cite="http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19716">Eurosurveillance - View Article</cite>. Abstract, edited.]
Eurosurveillance, Volume 15, Issue 46, 18 November 2010
Research articles
New Delhi metallo-beta-lactamase 1?producing Enterobacteriaceae: emergence and response in Europe
M. J. Struelens 1, D L Monnet 1, A P Magiorakos 1, F Santos O?Connor 1, J Giesecke 1, the European NDM-1 Survey Participants 2
1. European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden
2. The European NDM-1 Survey Participants are listed at the end of the article
Citation style for this article: Struelens MJ, Monnet DL, Magiorakos AP, Santos O?Connor F, Giesecke J, the European NDM-1 Survey Participants. New Delhi metallo-beta-lactamase 1?producing Enterobacteriaceae: emergence and response in Europe. Euro Surveill. 2010;15(46)
ii=19716. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19716Date of submission: 08 October 2010
Acquired carbapenemases confer extensive antibiotic resistance to Enterobacteriaceae and represent a public health threat. A novel acquired carbapenemase, New Delhi metallo-beta-lactamase 1 (NDM-1), has recently been described in the United Kingdom and Sweden, mostly in patients who had received care on the Indian subcontinent. We conducted a survey among 29 European countries (the European Union Member States, Iceland and Norway) to gather information on the spread of NDM-1-producing Enterobacteriaceae in Europe, on public health responses and on available national guidance on detection, surveillance and control. A total of 77 cases were reported from 13 countries from 2008 to 2010. Klebsiella pneumoniae was the most frequently reported species with 54%. Among 55 cases with recorded travel history, 31 had previously travelled or been admitted to a hospital in India or Pakistan and five had been hospitalised in the Balkan region. Possible nosocomial acquisition accounted for 13 of 77 cases. National guidance on NDM-1 detection was available in 14 countries and on NDM-1 control in 11 countries. In conclusion, NDM-1 is spreading across Europe, where it is frequently linked to a history of healthcare abroad, but also to emerging nosocomial transmission. National guidance in response to the threat of carbapenemase-producing Enterobacteriaceae is available in approximately half of the surveyed European countries. Surveillance of carbapenemase- producing Enterobacteriaceae must be enhanced in Europe and effective control measures identified and implemented.
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