tetano
Editor, Senior Moderator
Front Med (Lausanne)
. 2020 Jul 10;7:404.
doi: 10.3389/fmed.2020.00404. eCollection 2020.
Immune Thrombocytopenia in a Very Elderly Patient With Covid-19
Fehmi Hindilerden[SUP] 1 [/SUP], Ipek Yonal-Hindilerden[SUP] 2 [/SUP], Senoglu Sevtap[SUP] 3 [/SUP], Kadriye Kart-Yasar[SUP] 3 [/SUP]
Affiliations
Abstract
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), parvovirus, rubella, and measles. Association with the new severe acute respiratory syndrome coronavirus, SARS-CoV-2 infection (Covid-19 infection) has been rarely reported. Here, we report the oldest case of ITP patient triggered by the novel coronavirus infection. He showed inadequate response to IVIG but responded to corticosteroids with no severe adverse events. Further studies are warranted to determine the optimal therapeutic strategies for ITP with the Covid-19 infection.
Keywords: Covid-19; corticosteroids; immune thrombocytopenia; intravenous immunoglobulin; very old age.
. 2020 Jul 10;7:404.
doi: 10.3389/fmed.2020.00404. eCollection 2020.
Immune Thrombocytopenia in a Very Elderly Patient With Covid-19
Fehmi Hindilerden[SUP] 1 [/SUP], Ipek Yonal-Hindilerden[SUP] 2 [/SUP], Senoglu Sevtap[SUP] 3 [/SUP], Kadriye Kart-Yasar[SUP] 3 [/SUP]
Affiliations
- PMID: 32754609
- PMCID: PMC7365892
- DOI: 10.3389/fmed.2020.00404
Abstract
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), parvovirus, rubella, and measles. Association with the new severe acute respiratory syndrome coronavirus, SARS-CoV-2 infection (Covid-19 infection) has been rarely reported. Here, we report the oldest case of ITP patient triggered by the novel coronavirus infection. He showed inadequate response to IVIG but responded to corticosteroids with no severe adverse events. Further studies are warranted to determine the optimal therapeutic strategies for ITP with the Covid-19 infection.
Keywords: Covid-19; corticosteroids; immune thrombocytopenia; intravenous immunoglobulin; very old age.