tetano
Editor, Senior Moderator
Front Pediatr
. 2022 Mar 3;10:809061.
doi: 10.3389/fped.2022.809061. eCollection 2022.
Case Report: Severe Acute Pulmonary COVID-19 in a Teenager Post Autologous Hematopoietic Stem Cell Transplant
Fabian J S van der Velden[SUP] 1 2 [/SUP], Frederik van Delft[SUP] 3 [/SUP], Stephen Owens[SUP] 1 [/SUP], Judit Llevadias[SUP] 4 [/SUP], Michael McKean[SUP] 5 [/SUP], Lindsey Pulford[SUP] 4 [/SUP], Yusri Taha[SUP] 6 [/SUP], Grace Williamson[SUP] 7 [/SUP], Quentin Campbell-Hewson[SUP] 3 [/SUP], Sophie Hambleton[SUP] 1 2 [/SUP], Rebecca Payne[SUP] 2 [/SUP], Christopher Duncan[SUP] 2 8 [/SUP], Catriona Johnston[SUP] 9 [/SUP], Jarmila Spegarova[SUP] 2 [/SUP], Marieke Emonts[SUP] 1 2 [/SUP]
Affiliations
Abstract
Pulmonary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is generally described as mild, and SARS-CoV-2 infection in immunocompromised children are observed as generally mild as well. A small proportion of pediatric patients will become critically ill due to (cardio)respiratory failure and require intensive care treatment. We report the case of a teenager with Hodgkin's lymphoma who acquired SARS-CoV-2 (detected by PCR) on the day of her autologous stem cell transplant and developed acute respiratory distress syndrome, successfully treated with a combination of antivirals, immunomodulation with steroids and biologicals, and ECMO.
Keywords: COVID-19; immunodeficient; immunomodulation; pediatric; stem cell transplant.
. 2022 Mar 3;10:809061.
doi: 10.3389/fped.2022.809061. eCollection 2022.
Case Report: Severe Acute Pulmonary COVID-19 in a Teenager Post Autologous Hematopoietic Stem Cell Transplant
Fabian J S van der Velden[SUP] 1 2 [/SUP], Frederik van Delft[SUP] 3 [/SUP], Stephen Owens[SUP] 1 [/SUP], Judit Llevadias[SUP] 4 [/SUP], Michael McKean[SUP] 5 [/SUP], Lindsey Pulford[SUP] 4 [/SUP], Yusri Taha[SUP] 6 [/SUP], Grace Williamson[SUP] 7 [/SUP], Quentin Campbell-Hewson[SUP] 3 [/SUP], Sophie Hambleton[SUP] 1 2 [/SUP], Rebecca Payne[SUP] 2 [/SUP], Christopher Duncan[SUP] 2 8 [/SUP], Catriona Johnston[SUP] 9 [/SUP], Jarmila Spegarova[SUP] 2 [/SUP], Marieke Emonts[SUP] 1 2 [/SUP]
Affiliations
- PMID: 35311038
- PMCID: PMC8927762
- DOI: 10.3389/fped.2022.809061
Abstract
Pulmonary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is generally described as mild, and SARS-CoV-2 infection in immunocompromised children are observed as generally mild as well. A small proportion of pediatric patients will become critically ill due to (cardio)respiratory failure and require intensive care treatment. We report the case of a teenager with Hodgkin's lymphoma who acquired SARS-CoV-2 (detected by PCR) on the day of her autologous stem cell transplant and developed acute respiratory distress syndrome, successfully treated with a combination of antivirals, immunomodulation with steroids and biologicals, and ECMO.
Keywords: COVID-19; immunodeficient; immunomodulation; pediatric; stem cell transplant.