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Future Cardiol . Obese patients with long COVID-19 display abnormal hyperventilatory response and impaired gas exchange at peak exercise

tetano

Editor, Senior Moderator
Future Cardiol


. 2022 Jun 6.
doi: 10.2217/fca-2022-0017. Online ahead of print.
Obese patients with long COVID-19 display abnormal hyperventilatory response and impaired gas exchange at peak exercise


Mickael Rejaudry Lacavalerie[SUP] 1 2 [/SUP], Sandrine Pierre-Francois[SUP] 3 [/SUP], Moustapha Agossou[SUP] 4 [/SUP], Jocelyn Inamo[SUP] 2 5 [/SUP], André Cabie[SUP] 3 6 [/SUP], José Luis Barnay[SUP] 7 [/SUP], Rémi Neviere[SUP] 2 5 [/SUP]



Affiliations

Abstract

Aim: To analyze the impact of obesity on cardiopulmonary response to exercise in people with chronic post-coronavirus disease 2019 (COVID-19) syndrome. Patients & methods: Consecutive subjects with chronic post-COVID syndrome 6 months after nonsevere acute infection were included. All patients received a complete clinical evaluation, lung function tests and cardiopulmonary exercise testing. A total of 51 consecutive patients diagnosed with chronic post-COVID-19 were enrolled in this study. Results: More than half of patients with chronic post-COVID-19 had a significant alteration in aerobic exercise capacity (VO[SUB]2[/SUB]peak) 6 months after hospital discharge. Obese long-COVID-19 patients also displayed a marked reduction of oxygen pulse (O[SUB]2[/SUB]pulse). Conclusion: Obese patients were more prone to have pathological pulmonary limitation and pulmonary gas exchange impairment to exercise compared with nonobese COVID-19 patients.

Keywords: aerobic capacity (VO2); chronic post-COVID-19 syndrome; hyperventilation; obesity; oxygen pulse; pulse oxymetry.
 
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