tetano
Editor, Senior Moderator
Head Neck
. 2020 May 21.
doi: 10.1002/hed.26279. Online ahead of print.
Objective Olfactory Evaluation of Self-Reported Loss of Smell in a Case Series of 86 COVID-19 Patients
Jerome R Lechien[SUP] 1 2 3 4 [/SUP], Pierre Cabaraux[SUP] 1 2 3 4 5 [/SUP], Carlos M Chiesa-Estomba[SUP] 1 6 [/SUP], Mohamad Khalife[SUP] 1 7 [/SUP], St?phane Hans[SUP] 1 3 [/SUP], Christian Calvo-Henriquez[SUP] 1 8 [/SUP], Delphine Martiny[SUP] 9 10 [/SUP], Fabrice Journe[SUP] 1 2 [/SUP], Leigh Sowerby[SUP] 1 11 [/SUP], Sven Saussez[SUP] 2 4 7 [/SUP]
Affiliations
Abstract
Objective: To investigate olfactory dysfunction (OD) in patients with mild coronavirus disease 2019 (COVID-19) through patient-reported outcome questionnaires and objective psychophysical testing.
Methods: COVID-19 patients with self-reported sudden-onset OD were recruited. Epidemiological and clinical data were collected. Nasal complaints were evaluated with the sinonasal outcome-22. Subjective olfactory and gustatory status was evaluated with the National Health and Nutrition Examination Survey. Objective OD was evaluated using psychophysical tests.
Results: Eighty-six patients completed the study. The most common symptoms were fatigue (72.9%), headache (60.0%), nasal obstruction (58.6%), and postnasal drip (48.6%). Total loss of smell was self-reported by 61.4% of patients. Objective olfactory testings identified 41 anosmic (47.7%), 12 hyposmic (14.0%), and 33 normosmic (38.3%) patients. There was no correlation between the objective test results and subjective reports of nasal obstruction or postnasal drip.
Conclusion: A significant proportion of COVID-19 patients reporting OD do not have OD on objective testing.
Keywords: COVID-19; anosmia; coronavirus; evaluation; olfaction; olfactory; smell; taste.
. 2020 May 21.
doi: 10.1002/hed.26279. Online ahead of print.
Objective Olfactory Evaluation of Self-Reported Loss of Smell in a Case Series of 86 COVID-19 Patients
Jerome R Lechien[SUP] 1 2 3 4 [/SUP], Pierre Cabaraux[SUP] 1 2 3 4 5 [/SUP], Carlos M Chiesa-Estomba[SUP] 1 6 [/SUP], Mohamad Khalife[SUP] 1 7 [/SUP], St?phane Hans[SUP] 1 3 [/SUP], Christian Calvo-Henriquez[SUP] 1 8 [/SUP], Delphine Martiny[SUP] 9 10 [/SUP], Fabrice Journe[SUP] 1 2 [/SUP], Leigh Sowerby[SUP] 1 11 [/SUP], Sven Saussez[SUP] 2 4 7 [/SUP]
Affiliations
- PMID: 32437033
- DOI: 10.1002/hed.26279
Abstract
Objective: To investigate olfactory dysfunction (OD) in patients with mild coronavirus disease 2019 (COVID-19) through patient-reported outcome questionnaires and objective psychophysical testing.
Methods: COVID-19 patients with self-reported sudden-onset OD were recruited. Epidemiological and clinical data were collected. Nasal complaints were evaluated with the sinonasal outcome-22. Subjective olfactory and gustatory status was evaluated with the National Health and Nutrition Examination Survey. Objective OD was evaluated using psychophysical tests.
Results: Eighty-six patients completed the study. The most common symptoms were fatigue (72.9%), headache (60.0%), nasal obstruction (58.6%), and postnasal drip (48.6%). Total loss of smell was self-reported by 61.4% of patients. Objective olfactory testings identified 41 anosmic (47.7%), 12 hyposmic (14.0%), and 33 normosmic (38.3%) patients. There was no correlation between the objective test results and subjective reports of nasal obstruction or postnasal drip.
Conclusion: A significant proportion of COVID-19 patients reporting OD do not have OD on objective testing.
Keywords: COVID-19; anosmia; coronavirus; evaluation; olfaction; olfactory; smell; taste.