tetano
Editor, Senior Moderator
Health Res Policy Syst
. 2022 Mar 9;20(1):29.
doi: 10.1186/s12961-022-00821-6.
Rapid method through routine data to evaluate real-world vaccine effectiveness against coronavirus disease 2019 (COVID-19) infection: lessons from Thailand
Natthaprang Nittayasoot[SUP] 1 [/SUP], Panithee Thammawijaya[SUP] 1 [/SUP], Piyanit Tharmaphornpilas[SUP] 1 [/SUP], Chalo Sansilapin[SUP] 1 [/SUP], Chuleeporn Jiraphongsa[SUP] 1 [/SUP], Rapeepong Suphanchaimat[SUP] 2 3 [/SUP]
Affiliations
Abstract
The objective of this article is to draw lessons from the Thai experience in estimating vaccine effectiveness (VE) for coronavirus disease 2019 (COVID-19) based on routine service data. We found that a matched case-control design, using probability-based controls representing the varying vaccine coverage across the population over time, yielded a valid result for VE assessment. The proposed design has an advantage in its applicability drawing from the routine data monitoring system. Future studies that exercise other designs, such as test-negative and cohort studies, are recommended in order to compare and contrast the findings across different designs. To implement a continuous monitoring system on VE, the integration of data from different sources is needed. This requires long-term investment in the data monitoring system for the entire healthcare system.
Keywords: Case–control; Coronavirus disease 2019; Thailand; Vaccine effectiveness.
. 2022 Mar 9;20(1):29.
doi: 10.1186/s12961-022-00821-6.
Rapid method through routine data to evaluate real-world vaccine effectiveness against coronavirus disease 2019 (COVID-19) infection: lessons from Thailand
Natthaprang Nittayasoot[SUP] 1 [/SUP], Panithee Thammawijaya[SUP] 1 [/SUP], Piyanit Tharmaphornpilas[SUP] 1 [/SUP], Chalo Sansilapin[SUP] 1 [/SUP], Chuleeporn Jiraphongsa[SUP] 1 [/SUP], Rapeepong Suphanchaimat[SUP] 2 3 [/SUP]
Affiliations
- PMID: 35264194
- DOI: 10.1186/s12961-022-00821-6
Abstract
The objective of this article is to draw lessons from the Thai experience in estimating vaccine effectiveness (VE) for coronavirus disease 2019 (COVID-19) based on routine service data. We found that a matched case-control design, using probability-based controls representing the varying vaccine coverage across the population over time, yielded a valid result for VE assessment. The proposed design has an advantage in its applicability drawing from the routine data monitoring system. Future studies that exercise other designs, such as test-negative and cohort studies, are recommended in order to compare and contrast the findings across different designs. To implement a continuous monitoring system on VE, the integration of data from different sources is needed. This requires long-term investment in the data monitoring system for the entire healthcare system.
Keywords: Case–control; Coronavirus disease 2019; Thailand; Vaccine effectiveness.