tetano
Editor, Senior Moderator
Viral Immunol. 2019 May 9. doi: 10.1089/vim.2019.0010. [Epub ahead of print]
[h=1]Hemagglutination Inhibition Antibody Response Following Influenza A(H1N1)pdm09 Virus Natural Infection: A Cross-Sectional Study from Thirthahalli, Karnataka, India.[/h] Alladi CSH[SUP]1[/SUP], Jagadesh A[SUP]1[/SUP], Prabhu SG[SUP]1[/SUP], Arunkumar G[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza viruses are major respiratory pathogens that cause seasonal epidemics and occasional pandemics. Immune response to influenza viruses is majorly targeted against the hemagglutinin antigen. A laboratory-based retrospective cross-sectional study was conducted on 50 acute and 50 follow-up samples to assess the immune response to influenza A(H1N1)pdm09 virus after natural infection and detect the presence of pre-existing antibodies against influenza A(H3N2) and influenza B viruses. Two-fourfold rise in hemagglutination-inhibition (HAI) titer was observed in 100% of the follow-up samples for influenza A(H1N1)pdm09 virus. No change in HAI titers for influenza A(H3N2) and influenza B viruses was observed.
[h=4]KEYWORDS:[/h] hemagglutination-inhibition assay; immune response; influenza virus; pre-existing antibodies
PMID: 31070522 DOI: 10.1089/vim.2019.0010
[h=1]Hemagglutination Inhibition Antibody Response Following Influenza A(H1N1)pdm09 Virus Natural Infection: A Cross-Sectional Study from Thirthahalli, Karnataka, India.[/h] Alladi CSH[SUP]1[/SUP], Jagadesh A[SUP]1[/SUP], Prabhu SG[SUP]1[/SUP], Arunkumar G[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza viruses are major respiratory pathogens that cause seasonal epidemics and occasional pandemics. Immune response to influenza viruses is majorly targeted against the hemagglutinin antigen. A laboratory-based retrospective cross-sectional study was conducted on 50 acute and 50 follow-up samples to assess the immune response to influenza A(H1N1)pdm09 virus after natural infection and detect the presence of pre-existing antibodies against influenza A(H3N2) and influenza B viruses. Two-fourfold rise in hemagglutination-inhibition (HAI) titer was observed in 100% of the follow-up samples for influenza A(H1N1)pdm09 virus. No change in HAI titers for influenza A(H3N2) and influenza B viruses was observed.
[h=4]KEYWORDS:[/h] hemagglutination-inhibition assay; immune response; influenza virus; pre-existing antibodies
PMID: 31070522 DOI: 10.1089/vim.2019.0010