tetano
Editor, Senior Moderator
Influenza Other Respi Viruses. 2013 Sep;7 Suppl 2:54-8. doi: 10.1111/irv.12082.
Impact of H1N1 on socially disadvantaged populations: summary of a systematic review.
Tricco AC, Lillie E, Soobiah C, Perrier L, Straus SE.
Source
Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, ON, Canada.
Abstract
BACKGROUND:
Previous reviews found that the H1N1 pandemic was associated with a large proportion of hospitalizations, severe illness, workplace absenteeism, and high costs. However, the burden among socially disadvantaged groups of the population is unclear. This is a summary of a previously published systematic review commissioned by the World Health Organization on the burden of H1N1 pandemic (influenza A/Mexico/2009 (H1N1)) among socially disadvantaged populations.
METHODS:
MEDLINE and EMBASE were searched to identify studies reporting hospitalization, severe illness, and mortality attributable to the 2009 H1N1 pandemic among socially disadvantaged populations, including ethnic minorities and low-income or lower-middle-income economy countries (LIC/LMIC). SAS and Review Manager were used to conduct random effects meta-analysis.
RESULTS:
Forty-eight cohort studies and 14 companion reports including 44 777 patients were included after screening 787 citations and 164 full-text articles. Twelve of the included studies provided data on LIC/LMIC, including one study from Guatemala, two from Morocco, one from Pakistan, and eight from India, plus four companion reports. The rest provided data on ethnic minorities living in high-income economy countries (HIC). Significantly more hospitalizations were observed among ethnic minorities versus nonethnic minorities in two North American studies [1313 patients, odds ratio (OR) 2?26 (95% confidence interval: 1?53-3?32)]. Among hospitalized patients in HIC, statistically significant differences in intensive care unit admissions (n = 8 studies, 15 352 patients, OR 0?84 [0?69-1?02]) and deaths (n = 6 studies, 14 757 patients, OR 0?85 [95% CI: 0?73-1?01]) were not observed.
CONCLUSION:
We found significantly more hospitalizations among ethnic minorities versus nonethnic minorities in North America, yet no differences in intensive care unit admissions or deaths among H1N1-infected hospitalized patients were observed in North America and Australia. Our results suggest a similar burden of H1N1 between ethnic minorities and nonethnic minorities living in HIC.
? 2013 Blackwell Publishing Ltd.
KEYWORDS:
Ethnic minority, H1N1 subtype, influenza A, low-income country, low-middle-income country, vulnerable populations
PMID:
24034485
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/24034485
Impact of H1N1 on socially disadvantaged populations: summary of a systematic review.
Tricco AC, Lillie E, Soobiah C, Perrier L, Straus SE.
Source
Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, ON, Canada.
Abstract
BACKGROUND:
Previous reviews found that the H1N1 pandemic was associated with a large proportion of hospitalizations, severe illness, workplace absenteeism, and high costs. However, the burden among socially disadvantaged groups of the population is unclear. This is a summary of a previously published systematic review commissioned by the World Health Organization on the burden of H1N1 pandemic (influenza A/Mexico/2009 (H1N1)) among socially disadvantaged populations.
METHODS:
MEDLINE and EMBASE were searched to identify studies reporting hospitalization, severe illness, and mortality attributable to the 2009 H1N1 pandemic among socially disadvantaged populations, including ethnic minorities and low-income or lower-middle-income economy countries (LIC/LMIC). SAS and Review Manager were used to conduct random effects meta-analysis.
RESULTS:
Forty-eight cohort studies and 14 companion reports including 44 777 patients were included after screening 787 citations and 164 full-text articles. Twelve of the included studies provided data on LIC/LMIC, including one study from Guatemala, two from Morocco, one from Pakistan, and eight from India, plus four companion reports. The rest provided data on ethnic minorities living in high-income economy countries (HIC). Significantly more hospitalizations were observed among ethnic minorities versus nonethnic minorities in two North American studies [1313 patients, odds ratio (OR) 2?26 (95% confidence interval: 1?53-3?32)]. Among hospitalized patients in HIC, statistically significant differences in intensive care unit admissions (n = 8 studies, 15 352 patients, OR 0?84 [0?69-1?02]) and deaths (n = 6 studies, 14 757 patients, OR 0?85 [95% CI: 0?73-1?01]) were not observed.
CONCLUSION:
We found significantly more hospitalizations among ethnic minorities versus nonethnic minorities in North America, yet no differences in intensive care unit admissions or deaths among H1N1-infected hospitalized patients were observed in North America and Australia. Our results suggest a similar burden of H1N1 between ethnic minorities and nonethnic minorities living in HIC.
? 2013 Blackwell Publishing Ltd.
KEYWORDS:
Ethnic minority, H1N1 subtype, influenza A, low-income country, low-middle-income country, vulnerable populations
PMID:
24034485
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/24034485