tetano
Editor, Senior Moderator
Infect Drug Resist
. 2020 Sep 16;13:3217-3224.
doi: 10.2147/IDR.S264882. eCollection 2020.
ACEIs and ARBs and Their Correlation with COVID-19: A Review
Awgichew Shewasinad Yehualashet[SUP] 1 [/SUP], Teshome Fentik Belachew[SUP] 2 [/SUP]
Affiliations
Abstract
Although some animal studies suggested that the use of ACEIs/ARBs could contribute for the prevention and treatment of the effects of the COVID-19 infection, there are also contradictory scenarios indicating that their use may exacerbate the deleterious conditions of the infection. As a result of the paradoxical issue of using ACEIs/ARBs during COVID-19, it is still an area requiring extended investigation to prove. Additionally, a trial evidence of their efficacy and the possible benefit risk analysis of these conventional drugs during COVID-19 in connection with other comorbidities like hypertension, heart failure, and renal disease associated with diabetes should also be addressed.
Keywords: ACEIs; ARBs; COVID-19; coronavirus.
. 2020 Sep 16;13:3217-3224.
doi: 10.2147/IDR.S264882. eCollection 2020.
ACEIs and ARBs and Their Correlation with COVID-19: A Review
Awgichew Shewasinad Yehualashet[SUP] 1 [/SUP], Teshome Fentik Belachew[SUP] 2 [/SUP]
Affiliations
- PMID: 32982336
- PMCID: PMC7502385
- DOI: 10.2147/IDR.S264882
Abstract
Although some animal studies suggested that the use of ACEIs/ARBs could contribute for the prevention and treatment of the effects of the COVID-19 infection, there are also contradictory scenarios indicating that their use may exacerbate the deleterious conditions of the infection. As a result of the paradoxical issue of using ACEIs/ARBs during COVID-19, it is still an area requiring extended investigation to prove. Additionally, a trial evidence of their efficacy and the possible benefit risk analysis of these conventional drugs during COVID-19 in connection with other comorbidities like hypertension, heart failure, and renal disease associated with diabetes should also be addressed.
Keywords: ACEIs; ARBs; COVID-19; coronavirus.