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Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccinatio

Emily

Emily

Editor, Senior Moderator
https://www.journalofinfection.com/article/S0163-4453(21)00392-3/fulltext#

Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination?

Author: Nouara Yahi,Henri Chahinian,Jacques Fantini
Publication: Journal of Infection
Publisher:Elsevier
Date:Available online 9 August 2021
© 2021 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

Highlights
  • •Infection-enhancing antibodies have been detected in symptomatic Covid-19.
  • •Antibody dependent enhancement (ADE) is a potential concern for vaccines.
  • •Enhancing antibodies recognize both the Wuhan strain and delta variants.
  • •ADE of delta variants is a potential risk for current vaccines.
  • •Vaccine formulations lacking ADE epitope are suggested.
 
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